DE68911773D1 - Benzimidazol-Derivate mit pharmakologischer Aktivität. - Google Patents

Benzimidazol-Derivate mit pharmakologischer Aktivität.

Info

Publication number
DE68911773D1
DE68911773D1 DE89830312T DE68911773T DE68911773D1 DE 68911773 D1 DE68911773 D1 DE 68911773D1 DE 89830312 T DE89830312 T DE 89830312T DE 68911773 T DE68911773 T DE 68911773T DE 68911773 D1 DE68911773 D1 DE 68911773D1
Authority
DE
Germany
Prior art keywords
benzimidazole derivatives
inclusive
chem
integer
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE89830312T
Other languages
English (en)
Other versions
DE68911773T2 (de
Inventor
Roberto Giani
Ettore Parini
Giancarlo Tonon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dompe Farmaceutici SpA
Original Assignee
Dompe Farmaceutici SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dompe Farmaceutici SpA filed Critical Dompe Farmaceutici SpA
Publication of DE68911773D1 publication Critical patent/DE68911773D1/de
Application granted granted Critical
Publication of DE68911773T2 publication Critical patent/DE68911773T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/14—Radicals substituted by nitrogen atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S165/00—Heat exchange
    • Y10S165/009—Heat exchange having a solid heat storage mass for absorbing heat from one fluid and releasing it to another, i.e. regenerator
    • Y10S165/013—Movable heat storage mass with enclosure
    • Y10S165/016—Rotary storage mass
    • Y10S165/02—Seal and seal-engaging surface are relatively movable
    • Y10S165/024—Circumferential seal

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE68911773T 1988-07-07 1989-07-06 Benzimidazol-Derivate mit pharmakologischer Aktivität. Expired - Fee Related DE68911773T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8821271A IT1226100B (it) 1988-07-07 1988-07-07 Derivati benzimidazolici farmacologicamente attivi.

Publications (2)

Publication Number Publication Date
DE68911773D1 true DE68911773D1 (de) 1994-02-10
DE68911773T2 DE68911773T2 (de) 1994-07-07

Family

ID=11179331

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68911773T Expired - Fee Related DE68911773T2 (de) 1988-07-07 1989-07-06 Benzimidazol-Derivate mit pharmakologischer Aktivität.

Country Status (7)

Country Link
US (1) US4971980A (de)
EP (1) EP0350467B1 (de)
JP (1) JPH0267272A (de)
AT (1) ATE99295T1 (de)
DE (1) DE68911773T2 (de)
ES (1) ES2062098T3 (de)
IT (1) IT1226100B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2665161B1 (fr) * 1990-07-26 1992-11-27 Esteve Labor Dr Nouveaux derives de benzimidazole, leur preparation et leur application en tant que medicaments.
CA2097317C (en) * 1990-12-14 2002-02-12 Albert A. Carr Antiallergic piperdinyl benzimidazoles
TW263504B (de) 1991-10-03 1995-11-21 Pfizer
IT1264456B1 (it) * 1993-05-14 1996-09-23 Dompe Farmaceutici Spa Derivati del 2-(benzimidazol-2-il)-1,3-diaminopropano farmacologicamente attivi.
GB9413724D0 (en) * 1994-07-07 1994-08-24 Wellcome Found Therapeutic nucleosides
GB9600143D0 (en) 1996-01-05 1996-03-06 Wellcome Found Therapeutic compounds
KR100494448B1 (ko) * 1996-06-04 2005-12-02 화브리까 에스파놀라 데 프로둑또스 뀌미꼬스 이 화르마세우띠꼬스 쏘시에떼 아노님 항히스타민활성을가지는신규한벤조이미다졸유도체
EP0970100B1 (de) 1997-02-13 2003-11-12 Glaxo Group Limited Benzimidazolderivate
ES2205527T3 (es) 1997-06-10 2004-05-01 Glaxo Group Limited Derivados de bencimidazol.
WO1999006424A1 (en) 1997-07-30 1999-02-11 The Regents Of The University Of Michigan Lyxofuranosyl benzimidazoles as antiviral agents
AU775834B2 (en) * 1999-06-28 2004-08-19 Fuji Photo Film Co., Ltd. Benzimidazole compounds and medicaments comprising the same
EE04590B1 (et) * 1999-06-28 2006-02-15 Janssen Pharmaceutica N.V. Respiratoorse süntsütiaalviiruse replikatsiooni inhibiitorid, nende kasutamine ja valmistamismeetod, farmatseutiline kompositsioon ja selle valmistamismeetod ning produkt
DE60013607T2 (de) 1999-06-30 2005-09-29 Fuji Photo Film Co., Ltd., Minami-Ashigara Bemzimidazolverbindungen und medikamente die diese enthalten
KR20020022766A (ko) 1999-07-07 2002-03-27 무네유키 가코우 벤즈 이미다졸 화합물
US6349662B1 (en) * 2000-12-29 2002-02-26 Taco Metals, Inc. Rub rail
CN101374829A (zh) * 2005-12-19 2009-02-25 健泰科生物技术公司 Iap的抑制剂

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1023792A (en) * 1963-04-17 1966-03-23 Smith & Nephew Benzimidazole derivatives and processes for making them
US3362956A (en) * 1965-08-19 1968-01-09 Sterling Drug Inc 1-[(heterocyclyl)-lower-alkyl]-4-substituted-piperazines
US4462992A (en) * 1982-02-08 1984-07-31 Research Corporation Nitroimidazole radiosensitizers for hypoxic tumor cells and compositions thereof
JPS59199679A (ja) * 1983-04-27 1984-11-12 Kanebo Ltd 新規なベンズイミダゾ−ル誘導体、その製造法およびその医薬組成物
US4728741A (en) * 1985-01-08 1988-03-01 Smithkline Beckman Corporation 1-substituted-2-mercapto benzimidazole compounds and intermediates

Also Published As

Publication number Publication date
EP0350467B1 (de) 1993-12-29
IT8821271A0 (it) 1988-07-07
US4971980A (en) 1990-11-20
EP0350467A1 (de) 1990-01-10
ES2062098T3 (es) 1994-12-16
JPH0567624B2 (de) 1993-09-27
ATE99295T1 (de) 1994-01-15
JPH0267272A (ja) 1990-03-07
IT1226100B (it) 1990-12-10
DE68911773T2 (de) 1994-07-07

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee