UA5585A1 - Спосіб отримання похідних тіазолу та їх солей з лужними металами - Google Patents

Спосіб отримання похідних тіазолу та їх солей з лужними металами

Info

Publication number
UA5585A1
UA5585A1 UA4028404A UA4028404A UA5585A1 UA 5585 A1 UA5585 A1 UA 5585A1 UA 4028404 A UA4028404 A UA 4028404A UA 4028404 A UA4028404 A UA 4028404A UA 5585 A1 UA5585 A1 UA 5585A1
Authority
UA
Ukraine
Prior art keywords
salts
preparation
alkali metals
thiazole derivatives
thiazole
Prior art date
Application number
UA4028404A
Other languages
English (en)
Russian (ru)
Ukrainian (uk)
Inventor
Хаясі Єсіо
Огурі Томеі
Сінода Масакі
Цуцуі Мікіо
Такахасі Кацуо
Мііда Хітосі
Original Assignee
Міцубісі Касей Корпорейшн
Мицубиси Касей Корпорейшн
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Міцубісі Касей Корпорейшн, Мицубиси Касей Корпорейшн filed Critical Міцубісі Касей Корпорейшн
Publication of UA5585A1 publication Critical patent/UA5585A1/uk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/24—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/30—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
UA4028404A 1985-10-16 1986-10-15 Спосіб отримання похідних тіазолу та їх солей з лужними металами UA5585A1 (uk)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP60228912A JPS62142168A (ja) 1985-10-16 1985-10-16 チアゾ−ル誘導体及びそれを有効成分とするロイコトリエンきつ抗剤

Publications (1)

Publication Number Publication Date
UA5585A1 true UA5585A1 (uk) 1994-12-28

Family

ID=16883798

Family Applications (1)

Application Number Title Priority Date Filing Date
UA4028404A UA5585A1 (uk) 1985-10-16 1986-10-15 Спосіб отримання похідних тіазолу та їх солей з лужними металами

Country Status (11)

Country Link
US (1) US4902700A (OSRAM)
EP (1) EP0219436B1 (OSRAM)
JP (1) JPS62142168A (OSRAM)
KR (1) KR930006285B1 (OSRAM)
AU (1) AU603343B2 (OSRAM)
CA (1) CA1326034C (OSRAM)
DE (1) DE3689436T2 (OSRAM)
DK (1) DK169128B1 (OSRAM)
HU (1) HU203228B (OSRAM)
SU (1) SU1554763A3 (OSRAM)
UA (1) UA5585A1 (OSRAM)

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US5258395A (en) * 1984-11-12 1993-11-02 Yamanouchi Pharmaceutical Co., Ltd. Thiazole compounds as inhibitors of SRS-A
JPS63258854A (ja) * 1987-04-16 1988-10-26 Mitsubishi Kasei Corp カルボキシスチレン誘導体およびそれを有効成分とする薬剤
US4895953A (en) * 1987-09-30 1990-01-23 American Home Products Corporation 2-Aryl substituted heterocyclic compounds as antiallergic and antiinflammatory agents
US4826990A (en) * 1987-09-30 1989-05-02 American Home Products Corporation 2-aryl substituted heterocyclic compounds as antiallergic and antiinflammatory agents
US5037840A (en) * 1987-11-25 1991-08-06 Merck Frosst Canada, Inc. Benzothiazoles
US4962117A (en) * 1987-11-25 1990-10-09 Merck Frosst Canada, Inc. Heterazole dialkanoic acids
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CA1322005C (en) * 1987-11-25 1993-09-07 Robert N. Young Benzoheterazoles
US5004743A (en) * 1987-11-25 1991-04-02 Merck Frosst Canada, Inc. Pyridyl styrene dialkanoic acids as anti-leukotriene agents
ZA894913B (en) * 1988-07-12 1990-03-28 Ici Pharma Heterocyclic compounds
US5001140A (en) * 1989-04-17 1991-03-19 Hoffmann-La Roche Inc. Cycloalkylthiazoles
ES2052825T3 (es) * 1988-07-15 1994-07-16 Hoffmann La Roche Derivados de cicloalquiltiazol.
US5045554A (en) * 1988-11-29 1991-09-03 Monsanto Company Substituted thiazoles and their use as fungicides
JPH02169584A (ja) * 1988-12-22 1990-06-29 Mitsubishi Kasei Corp ビニルチアゾール誘導体およびそれを有効成分とする薬剤
US5089495A (en) * 1989-01-30 1992-02-18 Imperial Chemical Industries Plc Heterocyclic thiazole derivatives and pharmaceutical compositions comprising said derivatives
WO1990011278A1 (fr) * 1989-03-24 1990-10-04 The Green Cross Corporation Composes de thiazole et leurs applications
JPH03173874A (ja) * 1989-09-29 1991-07-29 Mitsubishi Kasei Corp 新規複素環化合物
WO1992000963A1 (fr) * 1990-07-12 1992-01-23 Yoshitomi Pharmaceutical Industries, Ltd. Composes de styryle et leur utilisation comme medicaments
JP2832923B2 (ja) * 1990-07-13 1998-12-09 吉富製薬株式会社 スチリル化合物およびその医薬用途
JP2600644B2 (ja) * 1991-08-16 1997-04-16 藤沢薬品工業株式会社 チアゾリルベンゾフラン誘導体
DE59310252D1 (de) * 1992-02-05 2002-01-24 Boehringer Ingelheim Pharma Neue Amiderivate, ihre Herstellung und Verwendung als Arzneimittel mit LTB4-antagonistischer Wirkung
CA2132724A1 (en) * 1992-04-10 1993-10-28 Robert Zamboni Thiazole-substituted benzyl alcohols as leukotriene antagonists
AU3884993A (en) * 1992-04-10 1993-11-18 Merck Frosst Canada Inc. Benzothiazole-substituted benzyl alcohols as leukotriene antagonists
DE4219765A1 (de) * 1992-06-17 1993-12-23 Bayer Ag Substituierte (Benzothiazolyl- und Chinoxalyl-methoxy)phenylessigsäurederivate
US5273986A (en) * 1992-07-02 1993-12-28 Hoffmann-La Roche Inc. Cycloalkylthiazoles
US5508408A (en) * 1993-09-10 1996-04-16 Ciba-Geigy Corporation Quinoline compound
WO1996033181A1 (en) * 1995-04-21 1996-10-24 Daiichi Pharmaceutical Co., Ltd. Ethynylthiazole derivative
AU1110497A (en) * 1995-12-14 1997-07-03 Kaken Pharmaceutical Co., Ltd. Thiazole derivatives
EP0999209B1 (en) * 1997-06-17 2006-11-02 Kaken Pharmaceutical Co., Ltd. 2-sulfamoylbenzoic acid derivatives
JP2004137284A (ja) * 1997-06-17 2004-05-13 Kaken Pharmaceut Co Ltd ２−スルファモイル安息香酸誘導体
US6376671B1 (en) 1997-06-17 2002-04-23 Kaken Pharmaceutical Co., Ltd. 2-sulfamoylbenzoic acid derivatives
US6083966A (en) * 1998-08-31 2000-07-04 University Of Florida Thiazoline acid derivatives
AU774956B2 (en) * 1998-09-21 2004-07-15 Trustees Of Columbia University In The City Of New York, The Antimalarial agents
EP1214303A1 (en) * 1999-08-31 2002-06-19 Merck & Co., Inc. Heterocyclic compounds and methods of use thereof
DE50009208D1 (de) 1999-11-25 2005-02-17 Ciba Sc Holding Ag Hydroxyphenylvinylthiazole
EP1103180B1 (de) * 1999-11-25 2005-01-12 Ciba SC Holding AG Hydroxyphenylvinylthiazole
CN1193020C (zh) * 2000-04-03 2005-03-16 伊哈拉化学工业株式会社 一种生产酰胺酸酯的方法
US7056917B2 (en) * 2001-04-26 2006-06-06 Daiichi Pharmaceutical Co., Ltd. Drug efflux pump inhibitor
EP1389463A4 (en) * 2001-04-26 2008-09-17 Daiichi Seiyaku Co MEDICAMENT FOR INHIBITING A DRUG REMOVAL PUMP
SE0102299D0 (sv) 2001-06-26 2001-06-26 Astrazeneca Ab Compounds
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GB0226930D0 (en) 2002-11-19 2002-12-24 Astrazeneca Ab Chemical compounds
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AU2003270473A1 (en) * 2003-09-09 2005-04-27 University Of Florida Desferrithiocin derivatives and their use as iron chelators
PE20060315A1 (es) * 2004-05-24 2006-05-15 Irm Llc Compuestos de tiazol como moduladores de ppar
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CN101189216B (zh) 2005-04-04 2011-10-19 佛罗里达大学研究基金会 Desferrithiocin聚醚类似物
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AR076221A1 (es) * 2009-04-09 2011-05-26 Astrazeneca Ab Derivado de pirazol [4,5-e] pirimidina y su uso para tratar diabetes y obesidad
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KR102268357B1 (ko) 2013-01-29 2021-06-23 아벡신 에이에스 항염증성 및 항종양성 2-옥소티아졸 및 2-옥소티오펜 화합물
EP3071201A4 (en) 2013-11-22 2017-04-26 University of Florida Research Foundation, Inc. Desferrithiocin analogs and uses thereof
GB201413695D0 (en) 2014-08-01 2014-09-17 Avexxin As Compound
WO2016176343A1 (en) 2015-04-27 2016-11-03 University Of Florida Research Foundation, Incorporated Metabolically programmed metal chelators and uses thereof
GB201604318D0 (en) 2016-03-14 2016-04-27 Avexxin As Combination therapy
US11919873B1 (en) 2023-08-29 2024-03-05 King Faisal University 1,3-benzothiazol-2-yl-N′-(benzoyloxy)ethanimidamide as an antitumor and antimicrobial compound
US11912676B1 (en) 2023-08-29 2024-02-27 King Faisal University N'-[(4-chlorobenzoyl)oxy]-1,3-benzothiazole-2-carboximidamide as an antitumor and antimicrobial compound

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DE1670908A1 (de) * 1967-08-16 1971-04-29 Hoechst Ag Neue Benzimidazolverbindungen,Verfahren zu ihrer Herstellung und ihre Verwendung als optische Aufhellungsmittel
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US4581457A (en) * 1984-09-21 1986-04-08 American Home Products Corporation Heterocyclic sulfonamides

Also Published As

Publication number Publication date
JPH057386B2 (OSRAM) 1993-01-28
US4902700A (en) 1990-02-20
AU603343B2 (en) 1990-11-15
DE3689436D1 (de) 1994-02-03
KR870004009A (ko) 1987-05-06
EP0219436B1 (en) 1993-12-22
SU1554763A3 (ru) 1990-03-30
DE3689436T2 (de) 1994-04-14
DK494186D0 (da) 1986-10-15
KR930006285B1 (ko) 1993-07-12
AU6393086A (en) 1987-04-30
EP0219436A3 (en) 1989-12-27
EP0219436A2 (en) 1987-04-22
HU203228B (en) 1991-06-28
DK169128B1 (da) 1994-08-22
JPS62142168A (ja) 1987-06-25
DK494186A (da) 1987-04-17
HUT47090A (en) 1989-01-30
CA1326034C (en) 1994-01-11

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