TWI844795B - 自噬活化劑 - Google Patents

自噬活化劑 Download PDF

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Publication number
TWI844795B
TWI844795B TW110134884A TW110134884A TWI844795B TW I844795 B TWI844795 B TW I844795B TW 110134884 A TW110134884 A TW 110134884A TW 110134884 A TW110134884 A TW 110134884A TW I844795 B TWI844795 B TW I844795B
Authority
TW
Taiwan
Prior art keywords
gene
autophagy
tocopherol
tocopherol phosphate
disease
Prior art date
Application number
TW110134884A
Other languages
English (en)
Chinese (zh)
Other versions
TW202228715A (zh
Inventor
中上夕子
Original Assignee
日商力森諾科股份有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 日商力森諾科股份有限公司 filed Critical 日商力森諾科股份有限公司
Publication of TW202228715A publication Critical patent/TW202228715A/zh
Application granted granted Critical
Publication of TWI844795B publication Critical patent/TWI844795B/zh

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/55—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Birds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
TW110134884A 2020-09-17 2021-09-17 自噬活化劑 TWI844795B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2020156458 2020-09-17
JP2020-156458 2020-09-17

Publications (2)

Publication Number Publication Date
TW202228715A TW202228715A (zh) 2022-08-01
TWI844795B true TWI844795B (zh) 2024-06-11

Family

ID=80776075

Family Applications (1)

Application Number Title Priority Date Filing Date
TW110134884A TWI844795B (zh) 2020-09-17 2021-09-17 自噬活化劑

Country Status (5)

Country Link
JP (1) JPWO2022059767A1 (https=)
KR (1) KR20230051262A (https=)
CN (1) CN116507314A (https=)
TW (1) TWI844795B (https=)
WO (1) WO2022059767A1 (https=)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1723019A (zh) * 2003-01-17 2006-01-18 生命健康科学有限公司 具有抗增殖属性的化合物
WO2020090881A1 (ja) * 2018-11-02 2020-05-07 昭和電工株式会社 水中油滴型皮膚外用剤

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1589964B1 (en) * 2003-01-17 2011-11-23 Vital Health Sciences Pty Ltd. Compounds having anti-proliferative properties
WO2013018779A1 (ja) 2011-08-01 2013-02-07 株式会社林原 α－グルコシルヘスペリジンの結晶とその用途
KR20170141705A (ko) 2015-04-08 2017-12-26 바이오멘딕스, 엘엘씨 상처 치유를 조절하기 위한 제형 및 방법
JP6740354B2 (ja) 2015-10-05 2020-08-12 ザ トラスティーズ オブ コロンビア ユニバーシティー イン ザ シティー オブ ニューヨーク オートファジーの流れ及びホスホリパーゼｄ及びタウを含むタンパク質凝集体のクリアランスの活性化剤ならびにタンパク質症の治療方法
JP7136765B2 (ja) 2017-03-24 2022-09-13 株式会社林原 オートファジー誘導剤とその用途
JP7399406B2 (ja) * 2019-03-04 2023-12-18 公立大学法人横浜市立大学 精子形成誘導用培地
JP7497850B2 (ja) * 2019-12-23 2024-06-11 株式会社アイ・ティー・オー 細胞送達用キャリア

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1723019A (zh) * 2003-01-17 2006-01-18 生命健康科学有限公司 具有抗增殖属性的化合物
WO2020090881A1 (ja) * 2018-11-02 2020-05-07 昭和電工株式会社 水中油滴型皮膚外用剤

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
期刊 , A GUGLIANDOLO, et al., "α-Tocopherol modulates non-amyloidogenic pathway and autophagy in an in vitro model of Alzheimer's disease: A transcriptional study", Brain Sci., 9, MDPI, 2019: 196. *

Also Published As

Publication number Publication date
WO2022059767A1 (ja) 2022-03-24
JPWO2022059767A1 (https=) 2022-03-24
KR20230051262A (ko) 2023-04-17
CN116507314A (zh) 2023-07-28
TW202228715A (zh) 2022-08-01

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