KR20230051262A - 오토파지 활성화제 - Google Patents

오토파지 활성화제 Download PDF

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Publication number
KR20230051262A
KR20230051262A KR1020237008830A KR20237008830A KR20230051262A KR 20230051262 A KR20230051262 A KR 20230051262A KR 1020237008830 A KR1020237008830 A KR 1020237008830A KR 20237008830 A KR20237008830 A KR 20237008830A KR 20230051262 A KR20230051262 A KR 20230051262A
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KR
South Korea
Prior art keywords
gene
autophagy
tocopherol
tocopherol phosphate
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
KR1020237008830A
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English (en)
Korean (ko)
Inventor
유코 나카가미
Original Assignee
가부시끼가이샤 레조낙
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 가부시끼가이샤 레조낙 filed Critical 가부시끼가이샤 레조낙
Publication of KR20230051262A publication Critical patent/KR20230051262A/ko
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/55—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Birds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020237008830A 2020-09-17 2021-09-17 오토파지 활성화제 Pending KR20230051262A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JPJP-P-2020-156458 2020-09-17
JP2020156458 2020-09-17
PCT/JP2021/034243 WO2022059767A1 (ja) 2020-09-17 2021-09-17 オートファジー活性化剤

Publications (1)

Publication Number Publication Date
KR20230051262A true KR20230051262A (ko) 2023-04-17

Family

ID=80776075

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020237008830A Pending KR20230051262A (ko) 2020-09-17 2021-09-17 오토파지 활성화제

Country Status (5)

Country Link
JP (1) JPWO2022059767A1 (https=)
KR (1) KR20230051262A (https=)
CN (1) CN116507314A (https=)
TW (1) TWI844795B (https=)
WO (1) WO2022059767A1 (https=)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018510902A (ja) 2015-04-08 2018-04-19 バイオメンディクス エルエルシー 創傷治癒調節のための製剤および方法
JP2018080204A (ja) 2011-08-01 2018-05-24 株式会社林原 α−グルコシルヘスペリジンの結晶とその用途
WO2018173653A1 (ja) 2017-03-24 2018-09-27 株式会社林原 オートファジー誘導剤とその用途
JP2019529514A (ja) 2015-10-05 2019-10-17 ザ トラスティーズ オブ コロンビア ユニバーシティー イン ザ シティー オブ ニューヨーク オートファジーフラックス及びホスホリパーゼｄ及びタウを含むタンパク質凝集体のクリアランスの活性化剤ならびにタンパク質症の治療方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1589964B1 (en) * 2003-01-17 2011-11-23 Vital Health Sciences Pty Ltd. Compounds having anti-proliferative properties
AU2003900200A0 (en) * 2003-01-17 2003-01-30 Vital Health Sciences Pty Ltd Compounds having antiproliferative properties
US20210401681A1 (en) * 2018-11-02 2021-12-30 Showa Denko K.K. Oil-in-water-type skin external agent
JP7399406B2 (ja) * 2019-03-04 2023-12-18 公立大学法人横浜市立大学 精子形成誘導用培地
JP7497850B2 (ja) * 2019-12-23 2024-06-11 株式会社アイ・ティー・オー 細胞送達用キャリア

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018080204A (ja) 2011-08-01 2018-05-24 株式会社林原 α−グルコシルヘスペリジンの結晶とその用途
JP2018510902A (ja) 2015-04-08 2018-04-19 バイオメンディクス エルエルシー 創傷治癒調節のための製剤および方法
JP2019529514A (ja) 2015-10-05 2019-10-17 ザ トラスティーズ オブ コロンビア ユニバーシティー イン ザ シティー オブ ニューヨーク オートファジーフラックス及びホスホリパーゼｄ及びタウを含むタンパク質凝集体のクリアランスの活性化剤ならびにタンパク質症の治療方法
WO2018173653A1 (ja) 2017-03-24 2018-09-27 株式会社林原 オートファジー誘導剤とその用途

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
Aaron Barnett et al., Autophagy in Aging and Alzheimer's Disease: Pathologic or Protective?. J Alzheimers Dis. 2011;25(3):385-394.
Marta M. Lipinski et al., Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease. Proc Natl Acad Sci USA. 2010, 107, 14164-14169.
Xiangqing Li et al., Cubeben induces autophagy via PI3K-AKT- mTOR pathway to protect primary neurons against amyloid beta in Alzheimer's disease. Cytotechnology(2019) 71:679-686.
Yogendra S. Rajawat et al., Aging: Central role for autophagy and the lysosomal degradative system. Ageing Research Reviews 8(2009) 199-213.
이노마타 등, 「오토파지와 노화의 관련성」, 기후켄 치과학회 잡지, 2018년, 제45권, 제1호, 1-7
카게야마 등, 「오토파지와 질환」, 영역 융합 리뷰, 2014년, 3, e006

Also Published As

Publication number Publication date
WO2022059767A1 (ja) 2022-03-24
JPWO2022059767A1 (https=) 2022-03-24
CN116507314A (zh) 2023-07-28
TWI844795B (zh) 2024-06-11
TW202228715A (zh) 2022-08-01

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