TWI811229B - 抗trem2抗體及其使用方法 - Google Patents
抗trem2抗體及其使用方法 Download PDFInfo
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- TWI811229B TWI811229B TW107126810A TW107126810A TWI811229B TW I811229 B TWI811229 B TW I811229B TW 107126810 A TW107126810 A TW 107126810A TW 107126810 A TW107126810 A TW 107126810A TW I811229 B TWI811229 B TW I811229B
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- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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| CA2955086A1 (en) | 2014-08-08 | 2016-02-11 | Alector Llc | Anti-trem2 antibodies and methods of use thereof |
| US10428143B2 (en) | 2014-09-28 | 2019-10-01 | The Regents Of The University Of California | Modulation of stimulatory and non-stimulatory myeloid cells |
| JOP20190248A1 (ar) | 2017-04-21 | 2019-10-20 | Amgen Inc | بروتينات ربط مولد ضد trem2 واستخداماته |
| TWI811229B (zh) | 2017-08-03 | 2023-08-11 | 美商阿列克特有限責任公司 | 抗trem2抗體及其使用方法 |
| EP3723803A4 (en) | 2017-12-12 | 2021-09-15 | Pionyr Immunotherapeutics, Inc. | ANTI-TREM2 ANTIBODIES AND RELATED PROCEDURES |
| CA3120970A1 (en) | 2018-11-26 | 2020-06-04 | Denali Therapeutics Inc. | Methods for treating dysregulated lipid metabolism |
| AR118144A1 (es) * | 2019-02-20 | 2021-09-22 | Denali Therapeutics Inc | Anticuerpos anti-trem2 y métodos para utilizarlos |
| CN114667295B (zh) | 2019-11-22 | 2024-03-29 | 伊莱利利公司 | Trem2抗体及其用途 |
| KR20220110537A (ko) | 2019-12-05 | 2022-08-08 | 알렉터 엘엘씨 | 항-trem2 항체 사용 방법 |
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| TWI890727B (zh) | 2020-01-13 | 2025-07-21 | 美商戴納立製藥公司 | 抗trem2 抗體及其使用方法 |
| US20230159637A1 (en) * | 2020-02-24 | 2023-05-25 | Alector Llc | Methods of use of anti-trem2 antibodies |
| KR20230005848A (ko) * | 2020-04-03 | 2023-01-10 | 알렉터 엘엘씨 | 항-trem2 항체의 사용 방법 |
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| TW202340235A (zh) | 2021-12-17 | 2023-10-16 | 美商戴納立製藥公司 | 多肽工程、文庫及工程ｃｄ９８重鏈以及轉鐵蛋白受體結合多肽 |
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| US12311033B2 (en) | 2023-05-31 | 2025-05-27 | Capstan Therapeutics, Inc. | Lipid nanoparticle formulations and compositions |
| WO2024253420A1 (ko) * | 2023-06-09 | 2024-12-12 | 재단법인대구경북과학기술원 | 인간 trem2 단백질에 특이적으로 결합하는 인간 항체 및 이의 용도 |
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| CN118546252A (zh) * | 2024-04-02 | 2024-08-27 | 上海宏成药业有限公司 | 抗trem2抗体及其用途 |
| WO2025217452A1 (en) | 2024-04-11 | 2025-10-16 | Capstan Therapeutics, Inc. | Constrained ionizable cationic lipids and lipid nanoparticles |
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