TWI781082B - 澱粉狀蛋白β纖維分解劑、起因於澱粉狀蛋白β之纖維化的疾病之治療藥、預防藥以及治療用、預防用食品組成物 - Google Patents

澱粉狀蛋白β纖維分解劑、起因於澱粉狀蛋白β之纖維化的疾病之治療藥、預防藥以及治療用、預防用食品組成物 Download PDF

Info

Publication number
TWI781082B
TWI781082B TW105122919A TW105122919A TWI781082B TW I781082 B TWI781082 B TW I781082B TW 105122919 A TW105122919 A TW 105122919A TW 105122919 A TW105122919 A TW 105122919A TW I781082 B TWI781082 B TW I781082B
Authority
TW
Taiwan
Prior art keywords
earthworms
amyloid
water
dry powder
therapeutic
Prior art date
Application number
TW105122919A
Other languages
English (en)
Chinese (zh)
Other versions
TW201716073A (zh
Inventor
石井陽一
岡本猛
石井紗也香
Original Assignee
日商井石有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 日商井石有限公司 filed Critical 日商井石有限公司
Publication of TW201716073A publication Critical patent/TW201716073A/zh
Application granted granted Critical
Publication of TWI781082B publication Critical patent/TWI781082B/zh

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23B—PRESERVATION OF FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES; CHEMICAL RIPENING OF FRUIT OR VEGETABLES
    • A23B2/00—Preservation of foods or foodstuffs, in general
    • A23B2/90—Preservation of foods or foodstuffs, in general by drying or kilning; Subsequent reconstitution
    • A23B2/92—Freeze drying
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L35/00—Foods or foodstuffs not provided for in groups A23L5/00 - A23L33/00; Preparation or treatment thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/62—Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00—Function of food ingredients
    • A23V2200/30—Foods, ingredients or supplements having a functional effect on health
    • A23V2200/322—Foods, ingredients or supplements having a functional effect on health having an effect on the health of the nervous system or on mental function
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2250/00—Food ingredients
    • A23V2250/15—Inorganic Compounds
    • A23V2250/156—Mineral combination
    • A23V2250/16—Potassium
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2250/00—Food ingredients
    • A23V2250/15—Inorganic Compounds
    • A23V2250/156—Mineral combination
    • A23V2250/161—Magnesium
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2250/00—Food ingredients
    • A23V2250/15—Inorganic Compounds
    • A23V2250/156—Mineral combination
    • A23V2250/1614—Sodium
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2300/00—Processes
    • A23V2300/18—Fractionation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Organic Chemistry (AREA)
  • Mycology (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
TW105122919A 2015-07-21 2016-07-20 澱粉狀蛋白β纖維分解劑、起因於澱粉狀蛋白β之纖維化的疾病之治療藥、預防藥以及治療用、預防用食品組成物 TWI781082B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2015144319A JP2017025019A (ja) 2015-07-21 2015-07-21 アミロイドβ線維分解剤、アミロイドβの線維化に起因する疾患の治療薬・予防薬および治療用・予防用食品組成物
JP2015-144319 2015-07-21

Publications (2)

Publication Number Publication Date
TW201716073A TW201716073A (zh) 2017-05-16
TWI781082B true TWI781082B (zh) 2022-10-21

Family

ID=57834025

Family Applications (1)

Application Number Title Priority Date Filing Date
TW105122919A TWI781082B (zh) 2015-07-21 2016-07-20 澱粉狀蛋白β纖維分解劑、起因於澱粉狀蛋白β之纖維化的疾病之治療藥、預防藥以及治療用、預防用食品組成物

Country Status (12)

Country Link
US (1) US20180147243A1 (enExample)
EP (1) EP3326636A4 (enExample)
JP (1) JP2017025019A (enExample)
KR (4) KR20210114551A (enExample)
CN (1) CN107405366B (enExample)
AU (2) AU2016296962B2 (enExample)
BR (1) BR112017027209A2 (enExample)
CA (1) CA2983905A1 (enExample)
PH (1) PH12017501949A1 (enExample)
RU (1) RU2018105718A (enExample)
TW (1) TWI781082B (enExample)
WO (1) WO2017014162A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6253837B1 (ja) * 2017-07-18 2017-12-27 エンチーム株式会社 組成物

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140154331A1 (en) * 2011-07-29 2014-06-05 Well Stone Co. Tyrosinase inhibitor produced using dried earthworm powder, and method for producing same

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08283157A (ja) 1995-02-15 1996-10-29 Takeda Chem Ind Ltd アミロイドβ蛋白産生・分泌阻害剤
JP4227245B2 (ja) 1999-04-30 2009-02-18 パナソニック株式会社 磁気ディスク用基板の製造方法
CN1753662A (zh) * 2002-12-24 2006-03-29 神经化学（国际）有限公司 用于治疗β－淀粉状蛋白相关疾病的治疗制剂
ITRM20050045A1 (it) * 2005-02-02 2006-08-03 Consiglio Nazionale Ricerche Proteina isolata da eisenia foetida simile all'ngf umano e usi relativi.
US8101578B2 (en) 2006-04-28 2012-01-24 Kagoshima University Amyloid [β] Beta fibrillogenesis-inhibiting peptide
JP4699974B2 (ja) * 2006-09-29 2011-06-15 Ｗｅｌｌ Ｓｔｏｎｅ 有限会社 ミミズ乾燥粉末の製造方法
US8137701B2 (en) * 2008-03-21 2012-03-20 Well Stone Co. Method of producing a dry earthworm powder
JP2009249362A (ja) * 2008-04-09 2009-10-29 Ｗｅｌｌ Ｓｔｏｎｅ 有限会社 無害化されたミミズ乾燥粉末の製造方法
US8137666B2 (en) * 2008-11-22 2012-03-20 Academia Sinica Nattokinase for degrading and reducing amyloid fibrils—associated with alzheimer's disease, prion diseases and other amyloidoses
JP4886017B2 (ja) * 2009-10-13 2012-02-29 Ｗｅｌｌ Ｓｔｏｎｅ 有限会社 ミミズ乾燥粉末の製造方法
JP4808822B1 (ja) * 2011-04-11 2011-11-02 Ｗｅｌｌ Ｓｔｏｎｅ 有限会社 ミミズ乾燥粉末の製造方法
CN103550537B (zh) * 2013-11-10 2014-08-06 孟晓彬 一种治疗阿尔茨海默病的中药制剂及制备方法
EP3097918B1 (en) * 2014-01-20 2019-04-03 Well Stone Co. Catecholamine production accelerator, and therapeutic and preventive agent and therapeutic and preventive food composition for diseases caused by catecholamine deficiency
CN104288396A (zh) * 2014-09-27 2015-01-21 隋荣玲 一种治疗老年痴呆症的中药汤剂
JP6321521B2 (ja) * 2014-11-04 2018-05-09 Ｗｅｌｌ Ｓｔｏｎｅ 有限会社 タウ蛋白産生促進剤、タウ蛋白の欠乏に起因する疾患の治療薬・予防薬および治療用・予防用食品組成物
CN104547388A (zh) * 2014-12-18 2015-04-29 黑龙江儒泰生物制药有限责任公司 治疗阿尔茨海默病的中药组合物、其制备方法和用途

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140154331A1 (en) * 2011-07-29 2014-06-05 Well Stone Co. Tyrosinase inhibitor produced using dried earthworm powder, and method for producing same

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
網路文獻 Biosci. Biotechnol. Biotechem., 63(11), 2031-2033,1999 *

Also Published As

Publication number Publication date
EP3326636A4 (en) 2019-03-27
KR20210114551A (ko) 2021-09-23
US20180147243A1 (en) 2018-05-31
WO2017014162A8 (ja) 2017-11-16
BR112017027209A2 (pt) 2018-10-30
WO2017014162A1 (ja) 2017-01-26
AU2022200329B2 (en) 2023-10-05
RU2018105718A (ru) 2019-08-22
PH12017501949A1 (en) 2018-03-19
KR20180029950A (ko) 2018-03-21
KR20210059023A (ko) 2021-05-24
EP3326636A1 (en) 2018-05-30
AU2016296962B2 (en) 2021-10-28
TW201716073A (zh) 2017-05-16
KR20220131357A (ko) 2022-09-27
JP2017025019A (ja) 2017-02-02
CA2983905A1 (en) 2017-01-26
AU2016296962A1 (en) 2018-01-04
AU2022200329A1 (en) 2022-02-17
KR102302013B1 (ko) 2021-09-13
CN107405366A (zh) 2017-11-28
KR102255146B1 (ko) 2021-05-21
CN107405366B (zh) 2022-07-22

Similar Documents

Publication Publication Date Title
TWI400070B (zh) 蚯蚓乾燥粉末之製造方法
TWI679981B (zh) 兒茶酚胺產生促進劑，起因於兒茶酚胺的缺乏之疾病的治療藥．預防藥及治療用．預防用食品組成物
TWI781082B (zh) 澱粉狀蛋白β纖維分解劑、起因於澱粉狀蛋白β之纖維化的疾病之治療藥、預防藥以及治療用、預防用食品組成物
TWI689311B (zh) 用於製造Ｔａｕ蛋白產生促進劑，起因於缺乏Ｔａｕ蛋白之疾病的治療藥．預防藥及治療用．預防用食品組成物之組成物的使用
HK1246154A1 (en) AMYLOID β FIBRIL DECOMPOSING AGENT, AND THERAPEUTIC OR PREVENTIVE AGENT FOR DISEASES CAUSED BY AMYLOID β FIBRIL FORMATION
HK1246154B (en) AMYLOID β FIBRIL DECOMPOSING AGENT, AND THERAPEUTIC OR PREVENTIVE AGENT FOR DISEASES CAUSED BY AMYLOID β FIBRIL FORMATION
HK1233168B (zh) 儿茶酚胺产生促进剂，起因於儿茶酚胺的缺乏的疾病的治疗药/预防药

Legal Events

Date Code Title Description
GD4A Issue of patent certificate for granted invention patent