WO2017014162A8 - アミロイドβ線維分解剤、アミロイドβの線維化に起因する疾患の治療薬・予防薬および治療用・予防用食品組成物 - Google Patents
アミロイドβ線維分解剤、アミロイドβの線維化に起因する疾患の治療薬・予防薬および治療用・予防用食品組成物 Download PDFInfo
- Publication number
- WO2017014162A8 WO2017014162A8 PCT/JP2016/070902 JP2016070902W WO2017014162A8 WO 2017014162 A8 WO2017014162 A8 WO 2017014162A8 JP 2016070902 W JP2016070902 W JP 2016070902W WO 2017014162 A8 WO2017014162 A8 WO 2017014162A8
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- amyloid
- therapeutic
- fibril
- preventive
- agent
- Prior art date
Links
- 102000013455 Amyloid beta-Peptides Human genes 0.000 title abstract 9
- 108010090849 Amyloid beta-Peptides Proteins 0.000 title abstract 9
- 230000015572 biosynthetic process Effects 0.000 title abstract 6
- 201000010099 disease Diseases 0.000 title abstract 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 6
- 230000003449 preventive effect Effects 0.000 title abstract 6
- 230000001225 therapeutic effect Effects 0.000 title abstract 6
- 239000000203 mixture Substances 0.000 title abstract 3
- 239000003795 chemical substances by application Substances 0.000 abstract 4
- 239000004480 active ingredient Substances 0.000 abstract 2
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 241000361919 Metaphire sieboldi Species 0.000 abstract 1
- 229930014626 natural product Natural products 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/62—Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
- A23L3/40—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by drying or kilning; Subsequent reconstitution
- A23L3/44—Freeze-drying
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L35/00—Food or foodstuffs not provided for in groups A23L5/00 – A23L33/00; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/322—Foods, ingredients or supplements having a functional effect on health having an effect on the health of the nervous system or on mental function
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2250/00—Food ingredients
- A23V2250/15—Inorganic Compounds
- A23V2250/156—Mineral combination
- A23V2250/16—Potassium
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2250/00—Food ingredients
- A23V2250/15—Inorganic Compounds
- A23V2250/156—Mineral combination
- A23V2250/161—Magnesium
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2250/00—Food ingredients
- A23V2250/15—Inorganic Compounds
- A23V2250/156—Mineral combination
- A23V2250/1614—Sodium
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2300/00—Processes
- A23V2300/18—Fractionation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Polymers & Plastics (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Tropical Medicine & Parasitology (AREA)
- Psychiatry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mycology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Priority Applications (13)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15/577,464 US20180147243A1 (en) | 2015-07-21 | 2016-07-14 | Amyloid beta fibril decomposing agent, and therapeutic or preventive agent and therapeutic or preventive food composition for diseases caused by amyloid beta fibril formation |
EP16827722.6A EP3326636A4 (en) | 2015-07-21 | 2016-07-14 | MEDIUM FOR THE REMOVAL OF AMYLOID BETA FIBRILLES AND A THERAPEUTIC OR PREVENTIVE AGENT AND THERAPEUTIC OR PREVENTIVE FOOD COMPOSITION FOR DISEASES CAUSED BY AMYLOID BETA FIBRILLATION |
KR1020217014598A KR102302013B1 (ko) | 2015-07-21 | 2016-07-14 | 아밀로이드β 섬유 분해제, 아밀로이드β의 섬유화에 기인하는 질환의 치료약·예방약 및 치료용·예방용 식품조성물 |
RU2018105718A RU2018105718A (ru) | 2015-07-21 | 2016-07-14 | СРЕДСТВО, РАЗРУШАЮЩЕЕ ФИБРИЛЛЫ АМИЛОИДА β, И ТЕРАПЕВТИЧЕСКИЙ ИЛИ ПРОФИЛАКТИЧЕСКИЙ АГЕНТ, И ТЕРАПЕВТИЧЕСКАЯ ИЛИ ПРОФИЛАКТИЧЕСКАЯ ПИЩЕВАЯ КОМПОЗИЦИЯ ДЛЯ ЗАБОЛЕВАНИЙ, ВЫЗВАННЫХ ОБРАЗОВАНИЕМ ФИБРИЛЛ АМИЛОИДА β |
KR1020227031896A KR20220131357A (ko) | 2015-07-21 | 2016-07-14 | 아밀로이드β 섬유 분해제, 아밀로이드β의 섬유화에 기인하는 질환의 치료약·예방약 및 치료용·예방용 식품조성물 |
KR1020177030221A KR102255146B1 (ko) | 2015-07-21 | 2016-07-14 | 아밀로이드β 섬유 분해제, 아밀로이드β의 섬유화에 기인하는 질환의 치료약·예방약 및 치료용·예방용 식품조성물 |
BR112017027209A BR112017027209A2 (pt) | 2015-07-21 | 2016-07-14 | agente de decomposição de fibrila beta amiloide e agente terapêutico ou de prevenção e composição alimentícia terapêutica ou de prevenção de doenças causadas pela formação de fibrila beta amiloide |
AU2016296962A AU2016296962B2 (en) | 2015-07-21 | 2016-07-14 | Amyloid beta fibril decomposing agent, and therapeutic or preventive agent and therapeutic or preventive food composition for diseases caused by amyloid beta fibril formation |
CN201680016841.9A CN107405366B (zh) | 2015-07-21 | 2016-07-14 | β淀粉样蛋白纤维分解剂、由β淀粉样蛋白的纤维化引起的疾病的治疗药/预防药 |
CA2983905A CA2983905A1 (en) | 2015-07-21 | 2016-07-14 | Amyloid .beta. fibril decomposing agent, and therapeutic or preventive agent and therapeutic or preventive food composition for diseases caused by amyloid .beta. fibril formation |
KR1020217028697A KR20210114551A (ko) | 2015-07-21 | 2016-07-14 | 아밀로이드β 섬유 분해제, 아밀로이드β의 섬유화에 기인하는 질환의 치료약·예방약 및 치료용·예방용 식품조성물 |
PH12017501949A PH12017501949A1 (en) | 2015-07-21 | 2017-10-25 | Amyloid � fibril decomposing agent, and therapeutic or preventive agent and therapeutic or preventive food composition for diseases caused by amyloid � fibril formation |
AU2022200329A AU2022200329B2 (en) | 2015-07-21 | 2022-01-19 | Amyloid beta fibril decomposing agent, and therapeutic or preventive agent and therapeutic or preventive food composition for diseases caused by amyloid beta fibril formation |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2015-144319 | 2015-07-21 | ||
JP2015144319A JP2017025019A (ja) | 2015-07-21 | 2015-07-21 | アミロイドβ線維分解剤、アミロイドβの線維化に起因する疾患の治療薬・予防薬および治療用・予防用食品組成物 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2017014162A1 WO2017014162A1 (ja) | 2017-01-26 |
WO2017014162A8 true WO2017014162A8 (ja) | 2017-11-16 |
Family
ID=57834025
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2016/070902 WO2017014162A1 (ja) | 2015-07-21 | 2016-07-14 | アミロイドβ線維分解剤、アミロイドβの線維化に起因する疾患の治療薬・予防薬および治療用・予防用食品組成物 |
Country Status (12)
Country | Link |
---|---|
US (1) | US20180147243A1 (ja) |
EP (1) | EP3326636A4 (ja) |
JP (1) | JP2017025019A (ja) |
KR (4) | KR20220131357A (ja) |
CN (1) | CN107405366B (ja) |
AU (2) | AU2016296962B2 (ja) |
BR (1) | BR112017027209A2 (ja) |
CA (1) | CA2983905A1 (ja) |
PH (1) | PH12017501949A1 (ja) |
RU (1) | RU2018105718A (ja) |
TW (1) | TWI781082B (ja) |
WO (1) | WO2017014162A1 (ja) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP6253837B1 (ja) * | 2017-07-18 | 2017-12-27 | エンチーム株式会社 | 組成物 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH08283157A (ja) | 1995-02-15 | 1996-10-29 | Takeda Chem Ind Ltd | アミロイドβ蛋白産生・分泌阻害剤 |
JP4227245B2 (ja) | 1999-04-30 | 2009-02-18 | パナソニック株式会社 | 磁気ディスク用基板の製造方法 |
CN101103969A (zh) * | 2002-12-24 | 2008-01-16 | 神经化学(国际)有限公司 | 治疗β淀粉样蛋白相关疾病的治疗性制品 |
ITRM20050045A1 (it) * | 2005-02-02 | 2006-08-03 | Consiglio Nazionale Ricerche | Proteina isolata da eisenia foetida simile all'ngf umano e usi relativi. |
JP5190957B2 (ja) | 2006-04-28 | 2013-04-24 | 国立大学法人 鹿児島大学 | アミロイドβ線維化阻害ペプチド |
JP4699974B2 (ja) * | 2006-09-29 | 2011-06-15 | Well Stone 有限会社 | ミミズ乾燥粉末の製造方法 |
US8137701B2 (en) * | 2008-03-21 | 2012-03-20 | Well Stone Co. | Method of producing a dry earthworm powder |
JP2009249362A (ja) * | 2008-04-09 | 2009-10-29 | Well Stone 有限会社 | 無害化されたミミズ乾燥粉末の製造方法 |
US8137666B2 (en) * | 2008-11-22 | 2012-03-20 | Academia Sinica | Nattokinase for degrading and reducing amyloid fibrils—associated with alzheimer's disease, prion diseases and other amyloidoses |
JP4886017B2 (ja) * | 2009-10-13 | 2012-02-29 | Well Stone 有限会社 | ミミズ乾燥粉末の製造方法 |
JP4808822B1 (ja) * | 2011-04-11 | 2011-11-02 | Well Stone 有限会社 | ミミズ乾燥粉末の製造方法 |
JP5243662B1 (ja) * | 2011-07-29 | 2013-07-24 | Well Stone 有限会社 | ミミズ乾燥粉末を用いたチロシナーゼ阻害剤およびその製造方法 |
CN103550537B (zh) * | 2013-11-10 | 2014-08-06 | 孟晓彬 | 一种治疗阿尔茨海默病的中药制剂及制备方法 |
KR101909168B1 (ko) * | 2014-01-20 | 2018-10-17 | 웰 스톤 유겐가이샤 | 카테콜라민 생산 촉진제, 카테콜라민의 결핍에 기인하는 질환의 치료약·예방약 및 치료용·예방용 식품 조성물 |
CN104288396A (zh) * | 2014-09-27 | 2015-01-21 | 隋荣玲 | 一种治疗老年痴呆症的中药汤剂 |
JP6321521B2 (ja) * | 2014-11-04 | 2018-05-09 | Well Stone 有限会社 | タウ蛋白産生促進剤、タウ蛋白の欠乏に起因する疾患の治療薬・予防薬および治療用・予防用食品組成物 |
CN104547388A (zh) * | 2014-12-18 | 2015-04-29 | 黑龙江儒泰生物制药有限责任公司 | 治疗阿尔茨海默病的中药组合物、其制备方法和用途 |
-
2015
- 2015-07-21 JP JP2015144319A patent/JP2017025019A/ja active Pending
-
2016
- 2016-07-14 CN CN201680016841.9A patent/CN107405366B/zh active Active
- 2016-07-14 RU RU2018105718A patent/RU2018105718A/ru not_active Application Discontinuation
- 2016-07-14 WO PCT/JP2016/070902 patent/WO2017014162A1/ja active Application Filing
- 2016-07-14 US US15/577,464 patent/US20180147243A1/en not_active Abandoned
- 2016-07-14 KR KR1020227031896A patent/KR20220131357A/ko not_active Application Discontinuation
- 2016-07-14 CA CA2983905A patent/CA2983905A1/en not_active Abandoned
- 2016-07-14 KR KR1020217028697A patent/KR20210114551A/ko not_active IP Right Cessation
- 2016-07-14 AU AU2016296962A patent/AU2016296962B2/en active Active
- 2016-07-14 KR KR1020217014598A patent/KR102302013B1/ko active IP Right Grant
- 2016-07-14 KR KR1020177030221A patent/KR102255146B1/ko active IP Right Grant
- 2016-07-14 BR BR112017027209A patent/BR112017027209A2/pt not_active Application Discontinuation
- 2016-07-14 EP EP16827722.6A patent/EP3326636A4/en active Pending
- 2016-07-20 TW TW105122919A patent/TWI781082B/zh active
-
2017
- 2017-10-25 PH PH12017501949A patent/PH12017501949A1/en unknown
-
2022
- 2022-01-19 AU AU2022200329A patent/AU2022200329B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
AU2016296962B2 (en) | 2021-10-28 |
CN107405366A (zh) | 2017-11-28 |
CN107405366B (zh) | 2022-07-22 |
TW201716073A (zh) | 2017-05-16 |
KR20180029950A (ko) | 2018-03-21 |
JP2017025019A (ja) | 2017-02-02 |
WO2017014162A1 (ja) | 2017-01-26 |
RU2018105718A (ru) | 2019-08-22 |
KR102302013B1 (ko) | 2021-09-13 |
BR112017027209A2 (pt) | 2018-10-30 |
US20180147243A1 (en) | 2018-05-31 |
KR20220131357A (ko) | 2022-09-27 |
PH12017501949A1 (en) | 2018-03-19 |
EP3326636A1 (en) | 2018-05-30 |
AU2022200329B2 (en) | 2023-10-05 |
EP3326636A4 (en) | 2019-03-27 |
KR20210059023A (ko) | 2021-05-24 |
KR102255146B1 (ko) | 2021-05-21 |
AU2016296962A1 (en) | 2018-01-04 |
TWI781082B (zh) | 2022-10-21 |
KR20210114551A (ko) | 2021-09-23 |
AU2022200329A1 (en) | 2022-02-17 |
CA2983905A1 (en) | 2017-01-26 |
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