TWI485134B - 取代的芳族化合物及其藥學用途 - Google Patents

取代的芳族化合物及其藥學用途 Download PDF

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TWI485134B
TWI485134B TW099114044A TW99114044A TWI485134B TW I485134 B TWI485134 B TW I485134B TW 099114044 A TW099114044 A TW 099114044A TW 99114044 A TW99114044 A TW 99114044A TW I485134 B TWI485134 B TW I485134B
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disease
compound
renal
alkyl
compounds
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TW201043601A (en
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鮑魯斯 扎恰里
克里斯多佛 班尼
萊尼 蓋格諾
珍 法蘭西斯 班佛奴
瓦勒里 佩容
布萊傑特 格魯伊克斯
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波麥堤克生化科學公司
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    • A61K31/19—Carboxylic acids, e.g. valproic acid
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Obesity (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Toxicology (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Psychiatry (AREA)
TW099114044A 2009-05-04 2010-05-03 取代的芳族化合物及其藥學用途 TWI485134B (zh)

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US17523509P 2009-05-04 2009-05-04

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TW201043601A TW201043601A (en) 2010-12-16
TWI485134B true TWI485134B (zh) 2015-05-21

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US (4) US8927765B2 (https=)
EP (1) EP2427416B1 (https=)
JP (2) JP2012526052A (https=)
KR (2) KR20120024696A (https=)
CN (1) CN102438975B (https=)
AU (1) AU2010244930B2 (https=)
BR (1) BRPI1015124B8 (https=)
CA (1) CA2761018C (https=)
DK (1) DK2427416T3 (https=)
EA (1) EA022445B1 (https=)
ES (1) ES2575100T3 (https=)
HU (1) HUE029126T2 (https=)
IL (1) IL216006A (https=)
MX (1) MX2011011757A (https=)
MY (1) MY156780A (https=)
NZ (1) NZ595978A (https=)
PL (1) PL2427416T3 (https=)
PT (1) PT2427416E (https=)
SG (1) SG175855A1 (https=)
TW (1) TWI485134B (https=)
WO (1) WO2010127440A1 (https=)

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MX2011011756A (es) * 2009-05-04 2012-01-25 Prometic Biosciences Inc Sales de acido 3-pentilfenilacetico y usos farmaceuticos.
PT2427416E (pt) 2009-05-04 2016-06-15 Prometic Pharma Smt Ltd Compostos aromáticos substituídos e seus usos farmacêuticos
AT509045B1 (de) * 2010-01-29 2011-06-15 Planta Naturstoffe Vertriebsges M B H Verbindungen zur behandlung von asthma bronchiale
MX365807B (es) * 2010-10-27 2019-06-14 Prometic Pharma Smt Ltd Compuestos y composiciones para el tratamiento del cáncer.
CA2816094A1 (en) * 2010-10-27 2012-07-26 Prometic Biosciences Inc. Compounds and pharmaceutical compositions for uses in diabetes
TWI742541B (zh) 2013-03-15 2021-10-11 英商邊緣生物科技有限公司 用於治療肺纖維化、肝纖維化、皮膚纖維化及心臟纖維化之經取代之芳族化合物
TWI689490B (zh) 2013-03-15 2020-04-01 英商邊緣生物科技有限公司 用於治療纖維化之經取代之芳族化合物及相關方法
CA2930584A1 (en) 2013-11-15 2015-05-21 The Wistar Institute Of Anatomy And Biology Ebna1 inhibitors and their method of use
GB201416017D0 (en) * 2014-09-10 2014-10-22 New Royal Holloway & Bedford An Anticonvulsant Compound
ES2785317T3 (es) * 2014-10-10 2020-10-06 Liminal Biosciences Ltd Compuestos aromáticos sustituidos y composiciones farmacéuticas para la prevención y el tratamiento de la osteoporosis
KR20170072352A (ko) * 2014-11-12 2017-06-26 프로메틱 파마 에스엠티 리미티드 조직 자가-회복 및 재생을 위한 치환된 방향족 화합물 및 약제학적 조성물
AU2016262572B2 (en) 2015-05-14 2020-04-30 The Wistar Institute Of Anatomy And Biology EBNA1 inhibitors and methods using same
EP3793546B1 (en) 2018-05-17 2025-11-19 The Wistar Institute Ebna1 inhibitor crystalline forms, and methods of preparing and using same
CN108997202A (zh) * 2018-07-10 2018-12-14 湖南华腾制药有限公司 一种（5-三氟甲基-吡啶-2-基）-乙酸盐的制备方法
MA53188A1 (fr) 2018-10-11 2021-12-31 Basf As Composés aromatiques et leurs utilisations pharmaceutiques
WO2020113340A1 (en) * 2018-12-05 2020-06-11 Liminal Biosciences Limited Use of sodium 2-(3-pentylphenyl)acetate in the treatment of alström syndrome
EP4051659B1 (en) * 2019-10-31 2026-01-28 Assia Chemical Industries Ltd. Solid state forms of fezagepras and process for preparation thereof
CN115974773B (zh) * 2022-12-30 2024-07-02 广东省科学院生物与医学工程研究所 甘蔗内生真菌所产的化合物及其在抑菌和抗氧化中的应用
WO2024217515A1 (zh) * 2023-04-19 2024-10-24 上海复宏汉霖生物技术股份有限公司 一种杂环取代的芳香化合物、其制备方法及用途

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