TWI439282B - 以血栓溶解劑治療中風之方法 - Google Patents
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- TWI439282B TWI439282B TW096128284A TW96128284A TWI439282B TW I439282 B TWI439282 B TW I439282B TW 096128284 A TW096128284 A TW 096128284A TW 96128284 A TW96128284 A TW 96128284A TW I439282 B TWI439282 B TW I439282B
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- Health & Medical Sciences (AREA)
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- Public Health (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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| US7759506B2 (en) | 2002-02-25 | 2010-07-20 | Diffusion Pharmaceuticals Llc | Bipolar trans carotenoid salts and their uses |
| EP2540696B1 (en) | 2005-02-24 | 2020-01-01 | Diffusion Pharmaceuticals LLC | Trans carotenoids, formulation and uses |
| BRPI0716143A2 (pt) | 2006-08-29 | 2013-11-26 | Genentech Inc | Uso de tenecteplase para tratar derrame isquêmico agudo |
| CN101687757A (zh) | 2007-04-13 | 2010-03-31 | 扩散药品有限公司 | 双极性反式类胡萝卜素作为预治疗及其在周围血管疾病的治疗中的应用 |
| US9034007B2 (en) | 2007-09-21 | 2015-05-19 | Insera Therapeutics, Inc. | Distal embolic protection devices with a variable thickness microguidewire and methods for their use |
| US20110257510A1 (en) * | 2008-12-24 | 2011-10-20 | Koninklijke Philips Electronics N.V. | System, method and apparatus for cardiac intervention with mr stroke detection and treatment |
| EP2445339B1 (en) * | 2009-06-22 | 2019-08-07 | Diffusion Pharmaceuticals LLC | Diffusion enhancing compound and its use with a thrombolytic |
| EP2470015B1 (en) * | 2009-08-24 | 2016-01-13 | Hough Ear Institute | Nitrone compounds for treating sensorineural hearing loss |
| AU2011262361A1 (en) | 2010-06-02 | 2013-01-10 | Diffusion Pharmaceuticals Llc | Oral formulations of bipolar trans carotenoids |
| JP6375112B2 (ja) * | 2010-12-23 | 2018-08-15 | ジェノヴァ バイオファーマシューティカルズ リミテッド | テネクテプラーゼの医薬組成物 |
| WO2014062888A1 (en) * | 2012-10-18 | 2014-04-24 | University Of South Florida | Compositions and methods for treating stroke |
| US8690907B1 (en) | 2013-03-15 | 2014-04-08 | Insera Therapeutics, Inc. | Vascular treatment methods |
| US8679150B1 (en) | 2013-03-15 | 2014-03-25 | Insera Therapeutics, Inc. | Shape-set textile structure based mechanical thrombectomy methods |
| CA2901443A1 (en) | 2013-03-15 | 2014-09-25 | Insera Therapeutics, Inc. | Vascular treatment devices and methods |
| US8715314B1 (en) | 2013-03-15 | 2014-05-06 | Insera Therapeutics, Inc. | Vascular treatment measurement methods |
| WO2015023830A1 (en) | 2013-08-14 | 2015-02-19 | Stc.Unm | Treatment and prevention of stroke and other neurological disorders |
| PL3209767T3 (pl) * | 2014-10-21 | 2021-01-11 | Gennova Biopharmaceuticals Ltd. | Nowy sposób oczyszczania do izolacji i komercyjnej produkcji zrekombinowanego tnk-tpa (tenekteplazy) |
| EP3416568A4 (en) | 2016-02-16 | 2019-10-16 | Insera Therapeutics, Inc. | SUCTION DEVICES AND ANCHORED FLOW REVERSING DEVICES |
| CA3018550A1 (en) | 2016-03-24 | 2017-09-28 | Diffusion Pharmaceuticals Llc | Use of bipolar trans carotenoids with chemotherapy and radiotherapy for treatment of cancer |
| EP3936140B1 (en) * | 2017-01-24 | 2023-08-30 | Boston Scientific Scimed, Inc. | Thrombolytic agent for the treatment of thromboembolism |
| EP3624832B1 (en) * | 2017-05-16 | 2025-08-20 | Institut National de la Santé et de la Recherche Médicale | Methods and pharmaceutical compositions for the treatment of acute ischemic stroke |
| US10426424B2 (en) | 2017-11-21 | 2019-10-01 | General Electric Company | System and method for generating and performing imaging protocol simulations |
| US20230068460A1 (en) * | 2020-02-04 | 2023-03-02 | The Regents Of The University Of Colorado, A Body Corporate | Prophylactic uses of annexin a2 |
| IL295727A (en) * | 2020-02-19 | 2022-10-01 | Nono Inc | Combined treatment of stroke with a plasmin-degradable and reperfusion psd-95 inhibitor |
| CN114984197A (zh) * | 2022-07-01 | 2022-09-02 | 江苏丰华生物制药有限公司 | 替奈普酶在制备用于治疗急性缺血性卒中的药物组合物中的应用 |
| CN115487294A (zh) * | 2022-07-12 | 2022-12-20 | 上海丰华天力通生物医药有限公司 | 替奈普酶在制备用于治疗轻型缺血性卒中的药物组合物中的应用 |
Family Cites Families (10)
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| US4485045A (en) | 1981-07-06 | 1984-11-27 | Research Corporation | Synthetic phosphatidyl cholines useful in forming liposomes |
| US4544545A (en) | 1983-06-20 | 1985-10-01 | Trustees University Of Massachusetts | Liposomes containing modified cholesterol for organ targeting |
| US5013556A (en) | 1989-10-20 | 1991-05-07 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| ATE155816T1 (de) | 1992-06-03 | 1997-08-15 | Genentech Inc | Varianten des gewebeplasminogenaktivators mit verbesserter therapeutischer wirkung |
| JP2002173447A (ja) * | 2000-09-29 | 2002-06-21 | Yamanouchi Pharmaceut Co Ltd | 脳塞栓症治療用医薬組成物 |
| US7084118B2 (en) * | 2002-02-22 | 2006-08-01 | Genentech, Inc. | Combination treatment with t-PA variant and low molecular weight heparin |
| US20030180282A1 (en) * | 2002-03-25 | 2003-09-25 | Victor Serebruany | Method of treatment of thrombotic events |
| US20070014779A1 (en) * | 2002-11-14 | 2007-01-18 | Genentech, Inc. | Plasminogen activator variant formulations |
| WO2006094120A2 (en) * | 2005-03-02 | 2006-09-08 | The Regents Of The University Of California | Treatment for embolic stroke |
| BRPI0716143A2 (pt) | 2006-08-29 | 2013-11-26 | Genentech Inc | Uso de tenecteplase para tratar derrame isquêmico agudo |
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2007
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- 2007-08-01 NZ NZ574767A patent/NZ574767A/en unknown
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- 2007-08-01 US US11/832,291 patent/US20080107641A1/en not_active Abandoned
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2011
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2016
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