TWI415833B - 脂氧素（ｌｉｐｏｘｉｎ）ａ4類似物之結晶鉀鹽 - Google Patents

脂氧素（ｌｉｐｏｘｉｎ）ａ4類似物之結晶鉀鹽 Download PDF

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TWI415833B
TWI415833B TW096146154A TW96146154A TWI415833B TW I415833 B TWI415833 B TW I415833B TW 096146154 A TW096146154 A TW 096146154A TW 96146154 A TW96146154 A TW 96146154A TW I415833 B TWI415833 B TW I415833B
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potassium salt
ray powder
powder diffraction
diffraction pattern
crystalline potassium
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TW096146154A
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Chinese (zh)
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TW200838847A (en
Inventor
哈客 堤洛
葛洛司貝區 丹賈
溫特 加布立爾
山得 邁可
貝克曼 沃夫岡
巴特爾 克勞斯
丁特 克力斯坦
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拜耳知識產權公司
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    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • C07C59/70—Ethers of hydroxy-acetic acid, e.g. substitutes on the ring
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    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/48—Unsaturated compounds containing hydroxy or O-metal groups containing six-membered aromatic rings
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    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
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TW096146154A 2006-12-04 2007-12-04 脂氧素（ｌｉｐｏｘｉｎ）ａ4類似物之結晶鉀鹽 TWI415833B (zh)

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US87283006P 2006-12-04 2006-12-04

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TW200838847A TW200838847A (en) 2008-10-01
TWI415833B true TWI415833B (zh) 2013-11-21

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US (2) US7906678B2 (enExample)
EP (2) EP3489214A1 (enExample)
JP (1) JP5410984B2 (enExample)
KR (3) KR20090101169A (enExample)
CN (1) CN101553456B (enExample)
AR (1) AR064116A1 (enExample)
AU (1) AU2007327765B2 (enExample)
BR (1) BRPI0719679A2 (enExample)
CA (1) CA2670791C (enExample)
CL (1) CL2007003468A1 (enExample)
CO (1) CO6190608A2 (enExample)
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DO (1) DOP2009000130A (enExample)
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EC (1) ECSP099380A (enExample)
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MA (1) MA31079B1 (enExample)
MX (1) MX2009005911A (enExample)
MY (1) MY147951A (enExample)
NO (1) NO20092528L (enExample)
NZ (1) NZ577338A (enExample)
PE (2) PE20120395A1 (enExample)
SV (1) SV2009003286A (enExample)
TN (1) TN2009000167A1 (enExample)
TW (1) TWI415833B (enExample)
UY (1) UY30755A1 (enExample)
WO (1) WO2008068041A1 (enExample)
ZA (1) ZA200904689B (enExample)

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US7906678B2 (en) * 2006-12-04 2011-03-15 Bayer Schering Pharma Aktiengesellschaft Crystalline potassium salt of lipoxin A4 analogs
US20090036530A1 (en) * 2006-12-04 2009-02-05 Bayer Schering Pharma Aktiengesellschaft Crystalline acid of lipoxin A4 analogs and method of making
EP2135610A1 (en) 2008-06-20 2009-12-23 Laboratorios Almirall, S.A. Combination comprising DHODH inhibitors and methotrexate
CN102470158A (zh) * 2009-08-27 2012-05-23 默沙东公司 制备丙型肝炎病毒的蛋白酶抑制剂的工艺方法
EP2958560B1 (en) * 2013-02-21 2019-05-08 Forsyth Dental Infirmary for Children Methods for increasing oral ostenogenesis using lipoxin a4 (lxa4) and its analogs
ES2895062T3 (es) * 2015-03-18 2022-02-17 Forsyth Dental Infirmary For Children Métodos para estabilizar placas ateroscleróticas usando lipoxinas, resolvinas y análogos de las mismas
JP6906047B2 (ja) 2016-06-03 2021-07-21 テティス・ファーマシューティカルズ・エルエルシー 特異的炎症収束性メディエーターの塩に関連する組成物及び方法
JP2020507761A (ja) 2017-01-31 2020-03-12 ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッドＴｈｅ Ｂｒｉｇｈａｍ ａｎｄ Ｗｏｍｅｎ’ｓ Ｈｏｓｐｉｔａｌ， Ｉｎｃ． 炎症系疾患の生化学的エンドタイプを定義するａｌｘ受容体リガンド
CN111875530A (zh) * 2020-08-17 2020-11-03 浙江朗华制药有限公司 一种普拉西坦水合物晶体及其制备方法

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EP2089350B1 (en) 2018-08-22
JP5410984B2 (ja) 2014-02-05
CL2007003468A1 (es) 2008-07-04
AU2007327765A1 (en) 2008-06-12
IL198434A (en) 2012-09-24
EA200900732A1 (ru) 2009-12-30
MX2009005911A (es) 2009-09-07
CR10837A (es) 2009-07-23
NO20092528L (no) 2009-08-26
CN101553456B (zh) 2013-08-28
US8049035B2 (en) 2011-11-01
CA2670791C (en) 2017-01-03
EP3489214A1 (en) 2019-05-29
TN2009000167A1 (en) 2010-10-18
CO6190608A2 (es) 2010-08-19
ECSP099380A (es) 2009-11-30
SV2009003286A (es) 2009-10-02
US20080182897A1 (en) 2008-07-31
ZA200904689B (en) 2011-10-26
US7906678B2 (en) 2011-03-15
CN101553456A (zh) 2009-10-07
KR20090101169A (ko) 2009-09-24
MY147951A (en) 2013-02-15
DOP2009000130A (es) 2009-08-15
KR20140135847A (ko) 2014-11-26
UY30755A1 (es) 2008-07-31
TW200838847A (en) 2008-10-01
CA2670791A1 (en) 2008-06-12
WO2008068041A1 (en) 2008-06-12
KR20160054030A (ko) 2016-05-13
BRPI0719679A2 (pt) 2014-01-14
MA31079B1 (fr) 2010-01-04
NZ577338A (en) 2011-02-25
JP2010511649A (ja) 2010-04-15
AR064116A1 (es) 2009-03-11
EP2089350A1 (en) 2009-08-19
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US20110124910A1 (en) 2011-05-26
EA018615B1 (ru) 2013-09-30
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