AU2007327765B2 - Crystalline potassium salt of lipoxin A4 analogs - Google Patents

Crystalline potassium salt of lipoxin A4 analogs Download PDF

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Publication number
AU2007327765B2
AU2007327765B2 AU2007327765A AU2007327765A AU2007327765B2 AU 2007327765 B2 AU2007327765 B2 AU 2007327765B2 AU 2007327765 A AU2007327765 A AU 2007327765A AU 2007327765 A AU2007327765 A AU 2007327765A AU 2007327765 B2 AU2007327765 B2 AU 2007327765B2
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AU
Australia
Prior art keywords
potassium salt
crystalline
crystalline potassium
monohydrate
dihydrate
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Ceased
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AU2007327765A
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English (en)
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AU2007327765A1 (en
Inventor
Klaus Bartel
Wolfgang Beckmann
Christian Dinter
Danja Grossbach
Tilo Haag
Michael Sander
Gabriele Winter
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The Brigham and Women's Hospital Inc
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Bayer Intellectual Property GmbH
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Publication of AU2007327765A1 publication Critical patent/AU2007327765A1/en
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Assigned to BAYER INTELLECTUAL PROPERTY GMBH reassignment BAYER INTELLECTUAL PROPERTY GMBH Request for Assignment Assignors: BAYER PHARMA AKTIENGESELLSCHAFT
Assigned to BRIGHAM AND WOMEN'S HOSPITAL, INC. reassignment BRIGHAM AND WOMEN'S HOSPITAL, INC. Request for Assignment Assignors: BAYER INTELLECTUAL PROPERTY GMBH
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • C07C59/70—Ethers of hydroxy-acetic acid, e.g. substitutes on the ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/48—Unsaturated compounds containing hydroxy or O-metal groups containing six-membered aromatic rings
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • C—CHEMISTRY; METALLURGY
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    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/41—Preparation of salts of carboxylic acids
    • C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

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  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
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  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Communicable Diseases (AREA)
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  • Otolaryngology (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
AU2007327765A 2006-12-04 2007-12-04 Crystalline potassium salt of lipoxin A4 analogs Ceased AU2007327765B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US87283006P 2006-12-04 2006-12-04
US60/872,830 2006-12-04
PCT/EP2007/010785 WO2008068041A1 (en) 2006-12-04 2007-12-04 Crystalline potassium salt of lipoxin a4 analogs

Publications (2)

Publication Number Publication Date
AU2007327765A1 AU2007327765A1 (en) 2008-06-12
AU2007327765B2 true AU2007327765B2 (en) 2012-04-12

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AU2007327765A Ceased AU2007327765B2 (en) 2006-12-04 2007-12-04 Crystalline potassium salt of lipoxin A4 analogs

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US (2) US7906678B2 (enExample)
EP (2) EP2089350B1 (enExample)
JP (1) JP5410984B2 (enExample)
KR (3) KR20090101169A (enExample)
CN (1) CN101553456B (enExample)
AR (1) AR064116A1 (enExample)
AU (1) AU2007327765B2 (enExample)
BR (1) BRPI0719679A2 (enExample)
CA (1) CA2670791C (enExample)
CL (1) CL2007003468A1 (enExample)
CO (1) CO6190608A2 (enExample)
CR (1) CR10837A (enExample)
DO (1) DOP2009000130A (enExample)
EA (1) EA018615B1 (enExample)
EC (1) ECSP099380A (enExample)
IL (1) IL198434A (enExample)
MA (1) MA31079B1 (enExample)
MX (1) MX2009005911A (enExample)
MY (1) MY147951A (enExample)
NO (1) NO20092528L (enExample)
NZ (1) NZ577338A (enExample)
PE (2) PE20081200A1 (enExample)
SV (1) SV2009003286A (enExample)
TN (1) TN2009000167A1 (enExample)
TW (1) TWI415833B (enExample)
UY (1) UY30755A1 (enExample)
WO (1) WO2008068041A1 (enExample)
ZA (1) ZA200904689B (enExample)

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US7906678B2 (en) * 2006-12-04 2011-03-15 Bayer Schering Pharma Aktiengesellschaft Crystalline potassium salt of lipoxin A4 analogs
US20090036530A1 (en) * 2006-12-04 2009-02-05 Bayer Schering Pharma Aktiengesellschaft Crystalline acid of lipoxin A4 analogs and method of making
EP2135610A1 (en) 2008-06-20 2009-12-23 Laboratorios Almirall, S.A. Combination comprising DHODH inhibitors and methotrexate
EP2470189A4 (en) * 2009-08-27 2013-01-23 Merck Sharp & Dohme METHOD FOR PRODUCING PROTEASE INHIBITORS OF HEPATITIS C VIRUS
DK2958560T3 (da) * 2013-02-21 2019-08-12 Forsyth Dental Infirmary For Children Fremgangsmåder til at øge oral osteogenese under anvendelse af lipoxin a4 (lxa4) og dets analoger
CN107438366B (zh) * 2015-03-18 2022-03-15 福塞斯儿童牙科医院 使用脂氧素、消退素及其类似物稳定动脉粥状硬化斑块的方法
KR102437682B1 (ko) * 2016-06-03 2022-08-29 테티스 파마수티컬스 엘엘씨 특화된 사전 해소 매개체의 염에 관한 조성물 및 방법
US11519911B2 (en) 2017-01-31 2022-12-06 The Brigham And Women's Hospital, Inc. ALX receptor ligands define a biochemical endotype for inflammation-based diseases
CN111875530A (zh) * 2020-08-17 2020-11-03 浙江朗华制药有限公司 一种普拉西坦水合物晶体及其制备方法

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NO20092528L (no) 2009-08-26
ZA200904689B (en) 2011-10-26
CL2007003468A1 (es) 2008-07-04
KR20140135847A (ko) 2014-11-26
PE20120395A1 (es) 2012-05-23
MX2009005911A (es) 2009-09-07
MY147951A (en) 2013-02-15
TWI415833B (zh) 2013-11-21
US8049035B2 (en) 2011-11-01
IL198434A (en) 2012-09-24
WO2008068041A1 (en) 2008-06-12
BRPI0719679A2 (pt) 2014-01-14
EP2089350A1 (en) 2009-08-19
JP2010511649A (ja) 2010-04-15
EA018615B1 (ru) 2013-09-30
US7906678B2 (en) 2011-03-15
CA2670791C (en) 2017-01-03
KR20160054030A (ko) 2016-05-13
KR20090101169A (ko) 2009-09-24
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US20110124910A1 (en) 2011-05-26
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AR064116A1 (es) 2009-03-11
EA200900732A1 (ru) 2009-12-30
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DOP2009000130A (es) 2009-08-15
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US20080182897A1 (en) 2008-07-31
CN101553456A (zh) 2009-10-07
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AU2007327765A1 (en) 2008-06-12
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CR10837A (es) 2009-07-23
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UY30755A1 (es) 2008-07-31

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