JP5410984B2 - リポキシンa4類似体の結晶カリウム塩 - Google Patents

リポキシンa4類似体の結晶カリウム塩 Download PDF

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JP5410984B2
JP5410984B2 JP2009539669A JP2009539669A JP5410984B2 JP 5410984 B2 JP5410984 B2 JP 5410984B2 JP 2009539669 A JP2009539669 A JP 2009539669A JP 2009539669 A JP2009539669 A JP 2009539669A JP 5410984 B2 JP5410984 B2 JP 5410984B2
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potassium salt
diffraction pattern
ray powder
powder diffraction
crystalline potassium
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Japanese (ja)
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JP2010511649A (ja
JP2010511649A5 (enExample
Inventor
ハーク,ティロ
グロスバッハ,ダンヤ
ビンター,ガブリエレ
サンダー,ミヒャエル
ベックマン,ボルフガンク
バルテル,クラウス
ディンター,クリスティアン
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Bayer Intellectual Property GmbH
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • C07C59/70—Ethers of hydroxy-acetic acid, e.g. substitutes on the ring
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  • Diabetes (AREA)
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  • Ophthalmology & Optometry (AREA)
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  • Otolaryngology (AREA)
  • Hematology (AREA)
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JP2009539669A 2006-12-04 2007-12-04 リポキシンa4類似体の結晶カリウム塩 Expired - Fee Related JP5410984B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US87283006P 2006-12-04 2006-12-04
US60/872,830 2006-12-04
PCT/EP2007/010785 WO2008068041A1 (en) 2006-12-04 2007-12-04 Crystalline potassium salt of lipoxin a4 analogs

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JP2010511649A JP2010511649A (ja) 2010-04-15
JP2010511649A5 JP2010511649A5 (enExample) 2013-10-31
JP5410984B2 true JP5410984B2 (ja) 2014-02-05

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US (2) US7906678B2 (enExample)
EP (2) EP2089350B1 (enExample)
JP (1) JP5410984B2 (enExample)
KR (3) KR20090101169A (enExample)
CN (1) CN101553456B (enExample)
AR (1) AR064116A1 (enExample)
AU (1) AU2007327765B2 (enExample)
BR (1) BRPI0719679A2 (enExample)
CA (1) CA2670791C (enExample)
CL (1) CL2007003468A1 (enExample)
CO (1) CO6190608A2 (enExample)
CR (1) CR10837A (enExample)
DO (1) DOP2009000130A (enExample)
EA (1) EA018615B1 (enExample)
EC (1) ECSP099380A (enExample)
IL (1) IL198434A (enExample)
MA (1) MA31079B1 (enExample)
MX (1) MX2009005911A (enExample)
MY (1) MY147951A (enExample)
NO (1) NO20092528L (enExample)
NZ (1) NZ577338A (enExample)
PE (2) PE20081200A1 (enExample)
SV (1) SV2009003286A (enExample)
TN (1) TN2009000167A1 (enExample)
TW (1) TWI415833B (enExample)
UY (1) UY30755A1 (enExample)
WO (1) WO2008068041A1 (enExample)
ZA (1) ZA200904689B (enExample)

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US7906678B2 (en) * 2006-12-04 2011-03-15 Bayer Schering Pharma Aktiengesellschaft Crystalline potassium salt of lipoxin A4 analogs
US20090036530A1 (en) * 2006-12-04 2009-02-05 Bayer Schering Pharma Aktiengesellschaft Crystalline acid of lipoxin A4 analogs and method of making
EP2135610A1 (en) 2008-06-20 2009-12-23 Laboratorios Almirall, S.A. Combination comprising DHODH inhibitors and methotrexate
EP2470189A4 (en) * 2009-08-27 2013-01-23 Merck Sharp & Dohme METHOD FOR PRODUCING PROTEASE INHIBITORS OF HEPATITIS C VIRUS
DK2958560T3 (da) * 2013-02-21 2019-08-12 Forsyth Dental Infirmary For Children Fremgangsmåder til at øge oral osteogenese under anvendelse af lipoxin a4 (lxa4) og dets analoger
CN107438366B (zh) * 2015-03-18 2022-03-15 福塞斯儿童牙科医院 使用脂氧素、消退素及其类似物稳定动脉粥状硬化斑块的方法
KR102437682B1 (ko) * 2016-06-03 2022-08-29 테티스 파마수티컬스 엘엘씨 특화된 사전 해소 매개체의 염에 관한 조성물 및 방법
US11519911B2 (en) 2017-01-31 2022-12-06 The Brigham And Women's Hospital, Inc. ALX receptor ligands define a biochemical endotype for inflammation-based diseases
CN111875530A (zh) * 2020-08-17 2020-11-03 浙江朗华制药有限公司 一种普拉西坦水合物晶体及其制备方法

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US6048897A (en) 1993-06-15 2000-04-11 Brigham And Women's Hospital Lipoxin compounds and their use in treating cell proliferative disorders
US5441951A (en) * 1994-06-15 1995-08-15 Brigham & Women's Hospital Lipoxin compounds
EP0703897B1 (en) 1993-06-15 2008-08-20 The Brigham And Women's Hospital, Inc. Lipoxin compounds with prolonged half-life
WO1995001179A1 (en) 1993-06-29 1995-01-12 Brigham & Women's Hospital Modulation of inflammation related to columnar epithelia
US6008205A (en) 1997-04-04 1999-12-28 The Brigham & Women's Hospital, Inc. Polyisoprenyl phosphate stable analogs for regulation of neutrophil responses
US6236978B1 (en) * 1997-11-14 2001-05-22 New York University System and method for dynamic profiling of users in one-to-one applications
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JP4392473B2 (ja) 1999-03-18 2010-01-06 ザ ブライハム アンド ウイメンズ ホスピタル, インコーポレイテッド ホスホリパーゼdの活性の調節
ES2246230T3 (es) 1999-03-18 2006-02-16 The Brigham And Women's Hospital, Inc. Compuestos de lipoxina y su utilizacion.
ES2249257T3 (es) 1999-03-18 2006-04-01 The Brigham And Women's Hospital, Inc. Utilizacion de compuestos de lipoxina para la inhibicion de la respuesta de los neutrofilos inducida por tnf-alfa.
ATE258791T1 (de) 1999-11-09 2004-02-15 Alcon Inc Lipoxin-a4 und deren analoge zur behandlung von trockenen augen
EP1268393A2 (en) 2000-03-20 2003-01-02 Trustees Of Boston University Lipoxin analogs and methods for the treatment of periodontal disease
US6831186B2 (en) * 2001-11-06 2004-12-14 Schering Aktiengesellschft Lipoxin A4 analogs
JP2005516011A (ja) 2001-12-13 2005-06-02 ランバクシー ラボラトリーズ リミテッド 結晶二水化セフニディールカリウム
US8377950B2 (en) 2002-03-15 2013-02-19 Dr. Reddy's Laboratories Limited Crystalline form of 5-[4-[[3-methyl-4-oxo-3,4-dihydroquinazolin-2-yl]methoxy]benzyl]thiazolidine-2,4-dione potassium salt
SI1589966T1 (sl) 2003-01-30 2011-06-30 Lek Pharmaceuticals D.D. Postopek čiščenja losartana
WO2006035291A1 (en) 2004-09-27 2006-04-06 Ranbaxy Laboratories Limited Crystalline forms of cefdinir potassium
US7223718B2 (en) * 2005-03-07 2007-05-29 Falcon Lab Llc Enhanced glyphosate herbicidal concentrates
JP2008525531A (ja) 2005-10-31 2008-07-17 テバ ファーマシューティカル インダストリーズ リミティド セフジニルカリウム塩の結晶形
US7906678B2 (en) * 2006-12-04 2011-03-15 Bayer Schering Pharma Aktiengesellschaft Crystalline potassium salt of lipoxin A4 analogs

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ZA200904689B (en) 2011-10-26
CL2007003468A1 (es) 2008-07-04
KR20140135847A (ko) 2014-11-26
PE20120395A1 (es) 2012-05-23
MX2009005911A (es) 2009-09-07
MY147951A (en) 2013-02-15
TWI415833B (zh) 2013-11-21
US8049035B2 (en) 2011-11-01
IL198434A (en) 2012-09-24
WO2008068041A1 (en) 2008-06-12
BRPI0719679A2 (pt) 2014-01-14
EP2089350A1 (en) 2009-08-19
JP2010511649A (ja) 2010-04-15
EA018615B1 (ru) 2013-09-30
US7906678B2 (en) 2011-03-15
CA2670791C (en) 2017-01-03
KR20160054030A (ko) 2016-05-13
KR20090101169A (ko) 2009-09-24
TN2009000167A1 (en) 2010-10-18
US20110124910A1 (en) 2011-05-26
CN101553456B (zh) 2013-08-28
CA2670791A1 (en) 2008-06-12
AU2007327765B2 (en) 2012-04-12
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