TWI329742B - - Google Patents
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- Publication number
- TWI329742B TWI329742B TW096116924A TW96116924A TWI329742B TW I329742 B TWI329742 B TW I329742B TW 096116924 A TW096116924 A TW 096116924A TW 96116924 A TW96116924 A TW 96116924A TW I329742 B TWI329742 B TW I329742B
- Authority
- TW
- Taiwan
- Prior art keywords
- foot
- mouth disease
- immunochromatographic test
- test piece
- nucleic acid
- Prior art date
Links
- 241000710198 Foot-and-mouth disease virus Species 0.000 claims description 63
- 238000012360 testing method Methods 0.000 claims description 61
- 208000007212 Foot-and-Mouth Disease Diseases 0.000 claims description 45
- 238000000034 method Methods 0.000 claims description 38
- 101710172711 Structural protein Proteins 0.000 claims description 29
- 108090000623 proteins and genes Proteins 0.000 claims description 23
- 238000001514 detection method Methods 0.000 claims description 22
- 241000700605 Viruses Species 0.000 claims description 17
- 108020004414 DNA Proteins 0.000 claims description 15
- 150000007523 nucleic acids Chemical group 0.000 claims description 12
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 claims description 11
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 claims description 11
- 239000002773 nucleotide Substances 0.000 claims description 11
- 125000003729 nucleotide group Chemical group 0.000 claims description 11
- 210000001124 body fluid Anatomy 0.000 claims description 9
- 108091028043 Nucleic acid sequence Proteins 0.000 claims description 8
- 239000010839 body fluid Substances 0.000 claims description 8
- 239000012634 fragment Substances 0.000 claims description 8
- 102000004169 proteins and genes Human genes 0.000 claims description 8
- 238000004519 manufacturing process Methods 0.000 claims description 7
- 238000003757 reverse transcription PCR Methods 0.000 claims description 7
- 238000013461 design Methods 0.000 claims description 6
- 108020004707 nucleic acids Proteins 0.000 claims description 6
- 102000039446 nucleic acids Human genes 0.000 claims description 6
- 238000006243 chemical reaction Methods 0.000 claims description 5
- 238000003556 assay Methods 0.000 claims description 4
- 230000009465 prokaryotic expression Effects 0.000 claims description 4
- 230000009466 transformation Effects 0.000 claims description 4
- 230000003612 virological effect Effects 0.000 claims description 4
- 108010067674 Viral Nonstructural Proteins Proteins 0.000 claims description 3
- 238000001042 affinity chromatography Methods 0.000 claims description 3
- 238000004458 analytical method Methods 0.000 claims description 3
- 239000002299 complementary DNA Substances 0.000 claims description 3
- 238000010276 construction Methods 0.000 claims description 3
- 238000003317 immunochromatography Methods 0.000 claims description 3
- 238000000746 purification Methods 0.000 claims description 3
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims description 2
- 238000003776 cleavage reaction Methods 0.000 claims description 2
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- 229910052737 gold Inorganic materials 0.000 description 2
- BPHPUYQFMNQIOC-NXRLNHOXSA-N isopropyl beta-D-thiogalactopyranoside Chemical compound CC(C)S[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O BPHPUYQFMNQIOC-NXRLNHOXSA-N 0.000 description 2
- 244000144972 livestock Species 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
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- 238000012123 point-of-care testing Methods 0.000 description 2
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- 208000006531 swine vesicular disease Diseases 0.000 description 2
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- 241000710189 Aphthovirus Species 0.000 description 1
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- 108010092799 RNA-directed DNA polymerase Proteins 0.000 description 1
- 241000714213 San Miguel sea lion virus Species 0.000 description 1
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- 101710140501 Sulfate adenylyltransferase subunit 2 1 Proteins 0.000 description 1
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- 101710137500 T7 RNA polymerase Proteins 0.000 description 1
- 101710120037 Toxin CcdB Proteins 0.000 description 1
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- RGWHQCVHVJXOKC-SHYZEUOFSA-J dCTP(4-) Chemical compound O=C1N=C(N)C=CN1[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O)[C@@H](O)C1 RGWHQCVHVJXOKC-SHYZEUOFSA-J 0.000 description 1
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- NHVNXKFIZYSCEB-XLPZGREQSA-N dTTP Chemical compound O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)C1 NHVNXKFIZYSCEB-XLPZGREQSA-N 0.000 description 1
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- 239000003102 growth factor Substances 0.000 description 1
- 210000000003 hoof Anatomy 0.000 description 1
- 230000003053 immunization Effects 0.000 description 1
- 238000002649 immunization Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 229940031551 inactivated vaccine Drugs 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
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- 238000003780 insertion Methods 0.000 description 1
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- 101150018420 kbp gene Proteins 0.000 description 1
- 239000004816 latex Substances 0.000 description 1
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- 239000000463 material Substances 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 210000002445 nipple Anatomy 0.000 description 1
- 244000309711 non-enveloped viruses Species 0.000 description 1
- 238000003199 nucleic acid amplification method Methods 0.000 description 1
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- 230000001717 pathogenic effect Effects 0.000 description 1
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- 230000000405 serological effect Effects 0.000 description 1
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- 235000015170 shellfish Nutrition 0.000 description 1
- 208000018556 stomach disease Diseases 0.000 description 1
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- 210000001519 tissue Anatomy 0.000 description 1
- 238000012549 training Methods 0.000 description 1
- 238000001890 transfection Methods 0.000 description 1
- 230000001131 transforming effect Effects 0.000 description 1
- 230000029812 viral genome replication Effects 0.000 description 1
- 230000001018 virulence Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TW096116924A TW200844441A (en) | 2007-05-11 | 2007-05-11 | Method of testing foot–and- mouth disease (FMD) by using immunochromatographic |
| US11/956,562 US20080280296A1 (en) | 2007-05-11 | 2007-12-14 | Method for detection of foot-and-mouth disease virus with chromatographic strip test |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TW096116924A TW200844441A (en) | 2007-05-11 | 2007-05-11 | Method of testing foot–and- mouth disease (FMD) by using immunochromatographic |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TW200844441A TW200844441A (en) | 2008-11-16 |
| TWI329742B true TWI329742B (https=) | 2010-09-01 |
Family
ID=39969884
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW096116924A TW200844441A (en) | 2007-05-11 | 2007-05-11 | Method of testing foot–and- mouth disease (FMD) by using immunochromatographic |
Country Status (2)
| Country | Link |
|---|---|
| US (1) | US20080280296A1 (https=) |
| TW (1) | TW200844441A (https=) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI392735B (zh) * | 2009-07-14 | 2013-04-11 | 行政院農業委員會家畜衛生試驗所 | 口蹄疫融合瘤細胞株、其單株抗體、及包含該單株抗體的ｅｌｉｓａ檢測試劑及套組 |
| KR101105833B1 (ko) | 2009-09-18 | 2012-01-13 | 주식회사 메디안디노스틱 | 구제역바이러스 아시아 １형 항체를 검출하기 위한 진단방법 |
| CN107663553A (zh) * | 2010-07-20 | 2018-02-06 | 贝克顿·迪金森公司 | 用于将及时现场护理快速诊断测试结果与基于实验室的方法相连的方法 |
| CN102288757A (zh) * | 2011-07-12 | 2011-12-21 | 珠海市银科医学工程有限公司 | 无创伤一步法胃幽门螺旋杆菌检测试剂盒及检测方法 |
| US20130102013A1 (en) * | 2011-10-21 | 2013-04-25 | Empire Technology Development Llc | Materials and methods to detect pyrimidine-pyrimidine dimer formation |
| IN2014DN09302A (https=) | 2012-04-13 | 2015-07-10 | Becton Dickinson Co | |
| CN102662063A (zh) * | 2012-04-25 | 2012-09-12 | 中国农业科学院兰州兽医研究所 | 口蹄疫病毒多种非结构蛋白抗体斑点印迹检测试剂盒及方法 |
| CN104788547A (zh) * | 2015-04-23 | 2015-07-22 | 吕宏亮 | 一种口蹄疫病毒2c3abc重组蛋白及其制备方法和应用 |
| CN105695628B (zh) * | 2016-03-07 | 2019-02-01 | 华南农业大学 | 一种鉴别猪口蹄疫病毒与猪塞内加谷病毒的hrm检测引物及方法 |
| CN106596932B (zh) * | 2016-11-25 | 2019-01-25 | 中国农业科学院兰州兽医研究所 | 一种猪口蹄疫3abc和2c抗体化学发光检测试剂盒 |
| CN106645685A (zh) * | 2016-11-30 | 2017-05-10 | 中国农业科学院兰州兽医研究所 | 一种用于测试动物a型口蹄疫的胶体金试纸及其制备方法 |
| CN106645682A (zh) * | 2016-11-30 | 2017-05-10 | 中国农业科学院兰州兽医研究所 | 一种用于检测AsiaI型口蹄疫的胶体金试纸及其制备方法 |
| CN109320606B (zh) * | 2017-08-01 | 2021-10-15 | 洛阳普泰生物技术有限公司 | 一种特异性结合口蹄疫非结构蛋白的单克隆抗体及其应用 |
| CN107870243A (zh) * | 2017-11-01 | 2018-04-03 | 中国农业科学院兰州兽医研究所 | 用于快速检测血清中口蹄疫病毒非结构蛋白抗体检测卡 |
| CN107860928A (zh) * | 2017-11-01 | 2018-03-30 | 中国农业科学院兰州兽医研究所 | 定量检测血清中Asia1型口蹄疫病毒抗体的检测卡 |
| CN108931644B (zh) * | 2018-07-19 | 2021-09-10 | 河南省农业科学院 | 一种口蹄疫病毒免疫抗体评价及感染与免疫鉴别诊断二联试纸条 |
| CN109187967B (zh) * | 2018-09-19 | 2021-10-01 | 郑州大学 | 一种检测并区分o型、a型口蹄疫病毒的双联快速检测卡及其制备方法 |
| CN109851662B (zh) * | 2018-12-24 | 2020-09-01 | 中国动物疫病预防控制中心（农业部屠宰技术中心） | 口蹄疫病毒重组蛋白及其相关生物材料与应用 |
| CN109765366A (zh) * | 2019-01-31 | 2019-05-17 | 中国农业科学院兰州兽医研究所 | 一种检测口蹄疫病毒3ab抗体的试剂盒及其检测方法 |
| CN111239409B (zh) * | 2020-01-19 | 2021-06-01 | 中国农业科学院兰州兽医研究所 | 用于o型口蹄疫病毒抗体定量检测的上转换发光免疫层析试纸条及其制备方法 |
| CN111239393A (zh) * | 2020-03-06 | 2020-06-05 | 中国农业科学院兰州兽医研究所 | 一种检测口蹄疫灭活抗原或灭活疫苗中NSPs残留的方法 |
| CN114276446B (zh) * | 2022-01-05 | 2023-04-18 | 中国农业科学院兰州兽医研究所 | 一种A型口蹄疫病毒结构蛋白VP2的抗体m12、制备方法及应用 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100531760B1 (ko) * | 2003-04-28 | 2005-11-29 | 대한민국(관리부서 : 농림부 국립수의과학검역원) | 구제역 바이러스의 감염여부를 진단하는 방법 및 이를구현하기 위한 진단키트 |
-
2007
- 2007-05-11 TW TW096116924A patent/TW200844441A/zh unknown
- 2007-12-14 US US11/956,562 patent/US20080280296A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| TW200844441A (en) | 2008-11-16 |
| US20080280296A1 (en) | 2008-11-13 |
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