TWI324069B - Herbal composition phy906 and its use in chemotherapy - Google Patents

Herbal composition phy906 and its use in chemotherapy Download PDF

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Publication number
TWI324069B
TWI324069B TW090105449A TW90105449A TWI324069B TW I324069 B TWI324069 B TW I324069B TW 090105449 A TW090105449 A TW 090105449A TW 90105449 A TW90105449 A TW 90105449A TW I324069 B TWI324069 B TW I324069B
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TW
Taiwan
Prior art keywords
licorice
yellow
peony
scutellaria
composition
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TW090105449A
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English (en)
Chinese (zh)
Inventor
Cheng Yung-Chi
Shwu-Huey Liu
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Univ Yale
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/72Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725Ziziphus, e.g. jujube
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
TW090105449A 2000-03-09 2001-03-08 Herbal composition phy906 and its use in chemotherapy TWI324069B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US52205500A 2000-03-09 2000-03-09

Publications (1)

Publication Number Publication Date
TWI324069B true TWI324069B (en) 2010-05-01

Family

ID=24079273

Family Applications (1)

Application Number Title Priority Date Filing Date
TW090105449A TWI324069B (en) 2000-03-09 2001-03-08 Herbal composition phy906 and its use in chemotherapy

Country Status (13)

Country Link
US (1) US7025993B2 (https=)
EP (1) EP1401458B1 (https=)
JP (3) JP5064630B2 (https=)
KR (1) KR100840213B1 (https=)
CN (1) CN100490845C (https=)
AT (1) ATE494899T1 (https=)
AU (1) AU4550801A (https=)
CA (1) CA2402466C (https=)
DE (1) DE60143857D1 (https=)
DK (1) DK1401458T3 (https=)
ES (1) ES2358639T3 (https=)
TW (1) TWI324069B (https=)
WO (1) WO2001066123A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111011136A (zh) * 2019-11-13 2020-04-17 云南中烟新材料科技有限公司 一种假秦艽的人工种植方法

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8871279B2 (en) 2000-03-09 2014-10-28 Yale University Use of the combination of PHY906 and a tyrosine kinase inhibitor as a cancer treatment regimen
US7534455B2 (en) * 2000-03-09 2009-05-19 Yale University Herbal composition PHY906 and its use in chemotherapy
DE60313754T2 (de) * 2002-03-06 2008-01-24 The Medical Research and Education Trust, San Diego Botanischer extrakt mit antikrebs-aktivität enthaltend isoliquiritigenin
RU2209062C1 (ru) * 2002-03-19 2003-07-27 Институт физиологии им. И.П.Павлова РАН Вещество, обладающее седативным действием
DE602005024923D1 (de) * 2004-02-13 2011-01-05 Yakult Honsha Kk Wässrige lösung mit einem camptothecin
CN101730535A (zh) 2007-02-15 2010-06-09 耶鲁大学 草药组合物phy906及其在化疗中的用途
JP2011500853A (ja) * 2007-10-25 2011-01-06 ファィトシューティカ, インコーポレイテッド 炎症性腸疾患および/または過敏性腸管症候群に対する処置としてのphy906の使用
WO2009067103A1 (en) * 2007-11-20 2009-05-28 Hewlett-Packard Development Company, L.P. Liquid handling device
KR100915457B1 (ko) * 2008-01-31 2009-09-04 세종대학교산학협력단 한국산 겨우살이 추출물이 함유된 미세캡슐을 유효성분으로포함하는 기능성 식품
TWI366466B (en) * 2008-05-08 2012-06-21 Ind Tech Res Inst Herbal extracts capable of inducing immune cells to produce interferon and activating toll-like receptors and the preparation thereof
EP2341918B1 (en) 2008-09-25 2018-02-28 Life Biotech Medical Research Ltd Herbal formulations
KR101138461B1 (ko) * 2010-02-12 2012-04-26 한국생명공학연구원 감초 추출물을 포함하는 로타바이러스 감염의 예방 또는 치료용 조성물
US8597695B1 (en) 2010-11-13 2013-12-03 Sirbal Ltd. Herbal combinations for treatment of a skin condition
US9066974B1 (en) 2010-11-13 2015-06-30 Sirbal Ltd. Molecular and herbal combinations for treating psoriasis
US9095606B1 (en) 2010-11-13 2015-08-04 Sirbal Ltd. Molecular and herbal combinations for treating psoriasis
US8541382B2 (en) 2010-11-13 2013-09-24 Sirbal Ltd. Cardiac glycoside analogs in combination with emodin for cancer therapy
CN102716421A (zh) * 2012-06-21 2012-10-10 中国人民解放军第三军医大学第一附属医院 治疗扁平疣的中药口服液及其制备方法
CN102698068B (zh) * 2012-07-02 2013-07-24 张秀香 一种预防化疗所致口腔黏膜炎的口腔护理液制备方法
KR101350143B1 (ko) * 2013-05-30 2014-01-16 재단법인 통합의료진흥원 반하 및 황금 생약 추출물을 포함하는 항암제로 인한 부작용의 경감용 조성물
WO2015082950A1 (en) 2013-12-02 2015-06-11 Sirbal Ltd. Herbal combinations for treatment of a skin condition
EP3328498B1 (en) 2015-07-29 2021-05-05 Sirbal Ltd. Medical kit comprising herbal combinations for treating psoriasis
JP2018523674A (ja) * 2015-08-21 2018-08-23 ザ メソディスト ホスピタル 腸カルボキシルエステラーゼ2酵素活性を選択的に阻害するための組成物及び方法
AU2017272098B2 (en) * 2016-05-23 2022-10-13 Yale University Improved therapeutic index of anti-immune checkpoint inhibitors using combination therapy comprising a PHY906 extract, a Scutellaria baicalensis GeorgI (S) extract or a compound from such extracts
KR102680200B1 (ko) * 2016-06-22 2024-07-02 예일 유니버시티 식물 의약을 위한 메커니즘 기반 품질 관리
JP7132344B2 (ja) * 2018-02-28 2022-09-06 チュンアン・ユニヴァーシティ・インダストリー・アカデミック・コーペレーション・ファウンデーション 悪液質および筋損失の予防、改善または治療用組成物
WO2019204471A1 (en) * 2018-04-20 2019-10-24 Yale University Treatment of hepatitis c
WO2020255133A1 (en) * 2019-06-18 2020-12-24 The Cures Ltd. Novel therapeutic preparations comprising scutellaria barbata
EP4087585A4 (en) * 2019-12-09 2023-12-06 Yale University COMPOSITIONS AND METHODS FOR PREVENTING CANCER RECURRENCE
TW202200183A (zh) * 2020-03-30 2022-01-01 耶魯大學 治療炎性和纖維化疾病和病症的方法
CN114642732A (zh) * 2020-12-21 2022-06-21 苏州普瑞森生物科技有限公司 一种组合物及其在制备治疗肿瘤的药物中的应用
TW202337484A (zh) * 2022-03-01 2023-10-01 耶魯大學 用於調節t細胞之活化t細胞核因子(nfat)活性的組成物及方法
CN116712507B (zh) * 2023-08-10 2023-10-20 中国人民解放军总医院第六医学中心 一种辅助乳腺癌化疗的中药组合物及其制备方法、应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5936619A (ja) 1982-08-23 1984-02-28 Tsumura Juntendo Inc 制癌補助剤
JPS5936621A (ja) 1982-08-25 1984-02-28 Tsumura Juntendo Inc 脂肪分解促進作用阻害剤
WO1991006307A1 (en) 1989-11-03 1991-05-16 Sun Alexander S Herbal treatment of malignancy
US5665393A (en) 1996-09-03 1997-09-09 International Medical Research, Inc. Herbal composition for treating prostate carcinoma
US6048847A (en) 1997-09-30 2000-04-11 Dabur Research Foundation Use of betulinic acid and its derivatives for inhibiting cancer growth and a method of monitoring this

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111011136A (zh) * 2019-11-13 2020-04-17 云南中烟新材料科技有限公司 一种假秦艽的人工种植方法
CN111011136B (zh) * 2019-11-13 2021-11-02 云南中烟新材料科技有限公司 一种假秦艽的人工种植方法

Also Published As

Publication number Publication date
ATE494899T1 (de) 2011-01-15
CA2402466C (en) 2014-11-18
DE60143857D1 (de) 2011-02-24
AU4550801A (en) 2001-09-17
JP2014208684A (ja) 2014-11-06
JP2012167101A (ja) 2012-09-06
KR20020086627A (ko) 2002-11-18
WO2001066123A2 (en) 2001-09-13
US20030211180A1 (en) 2003-11-13
EP1401458B1 (en) 2011-01-12
JP5064630B2 (ja) 2012-10-31
DK1401458T3 (da) 2011-05-09
JP2004500390A (ja) 2004-01-08
WO2001066123A3 (en) 2004-01-08
KR100840213B1 (ko) 2008-06-23
CN100490845C (zh) 2009-05-27
CA2402466A1 (en) 2001-09-13
CN1612743A (zh) 2005-05-04
EP1401458A2 (en) 2004-03-31
ES2358639T3 (es) 2011-05-12
US7025993B2 (en) 2006-04-11

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