TW301655B - - Google Patents

Download PDF

Info

Publication number
TW301655B
TW301655B TW083104367A TW83104367A TW301655B TW 301655 B TW301655 B TW 301655B TW 083104367 A TW083104367 A TW 083104367A TW 83104367 A TW83104367 A TW 83104367A TW 301655 B TW301655 B TW 301655B
Authority
TW
Taiwan
Prior art keywords
group
compound
page
cns
formula
Prior art date
Application number
TW083104367A
Other languages
English (en)
Chinese (zh)
Original Assignee
Fujisawa Yakusin Kogyo Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB939310091A external-priority patent/GB9310091D0/en
Priority claimed from GB939325269A external-priority patent/GB9325269D0/en
Application filed by Fujisawa Yakusin Kogyo Kk filed Critical Fujisawa Yakusin Kogyo Kk
Application granted granted Critical
Publication of TW301655B publication Critical patent/TW301655B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
TW083104367A 1993-05-17 1994-05-14 TW301655B (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939310091A GB9310091D0 (en) 1993-05-17 1993-05-17 New polypeptide compound and a process for preparation thereof
GB939325269A GB9325269D0 (en) 1993-12-10 1993-12-10 New polypeptide compound and a process for preparation thereof

Publications (1)

Publication Number Publication Date
TW301655B true TW301655B (pt) 1997-04-01

Family

ID=26302903

Family Applications (1)

Application Number Title Priority Date Filing Date
TW083104367A TW301655B (pt) 1993-05-17 1994-05-14

Country Status (18)

Country Link
US (2) US5569646A (pt)
EP (1) EP0644199B1 (pt)
JP (1) JP3551469B2 (pt)
KR (1) KR100346489B1 (pt)
CN (1) CN1057306C (pt)
AT (1) ATE194846T1 (pt)
AU (1) AU681119B2 (pt)
CA (1) CA2123921A1 (pt)
DE (1) DE69425304T2 (pt)
DK (1) DK0644199T3 (pt)
ES (1) ES2148254T3 (pt)
GR (1) GR3034366T3 (pt)
HU (1) HUT68385A (pt)
IL (1) IL109615A (pt)
PH (1) PH30811A (pt)
PT (1) PT644199E (pt)
RU (1) RU2164230C2 (pt)
TW (1) TW301655B (pt)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5874403A (en) * 1992-10-15 1999-02-23 Merck & Co., Inc. Amino acid conjugates of cyclohexapeptidyl amines
US5948753A (en) * 1993-05-04 1999-09-07 Merck & Co., Inc. Cyclohexapeptidyl propanolamine compounds
US5854276A (en) * 1995-06-29 1998-12-29 Fujisawa Pharmaceutical Co., Ltd. Substance WF16616, process for production thereof, and use thereof
WO1997017365A1 (en) * 1995-11-09 1997-05-15 Merck & Co., Inc. Cyclohexapeptidyl bisamine compound, compositions containing said compound and methods of use
US6117641A (en) 1996-04-11 2000-09-12 Mitotix, Inc. Assays and reagents for identifying anti-fungal agents and uses related thereto
KR20000005397A (ko) 1996-04-11 2000-01-25 맨수리 무잠밀 엠 항-진균제를확인하기위한검정방법및시약,및이의용도
US6727082B1 (en) 1996-04-11 2004-04-27 Gpc Biotech Inc. Assays and reagents for identifying anti-fungal agents, and uses related thereto
US5854212A (en) * 1996-10-23 1998-12-29 Merck & Co., Inc. Cyclohexapeptidyl bisamine compound, compositions containing said compound and methods of use
AUPO381496A0 (en) * 1996-11-25 1996-12-19 Fujisawa Pharmaceutical Co., Ltd. New compound
CN1240713C (zh) * 1998-02-09 2006-02-08 藤泽药品工业株式会社 化合物
WO1999047551A1 (en) * 1998-03-16 1999-09-23 Fujisawa Pharmaceutical Co., Ltd. Wf14573 or its salt, production thereof and use thereof
DE69934683T2 (de) 1998-04-23 2007-10-18 Aventis Pharma Deutschland Gmbh Verfahren zur reduzierung von echinocandin-peptiden zu deren c4-monodeoxyhomotyrosin analoga
AU6408499A (en) * 1998-10-05 2000-04-26 Abbott Laboratories Cyclic peptides as antifungal agents
AUPP999799A0 (en) 1999-04-27 1999-05-20 Fujisawa Pharmaceutical Co., Ltd. New compound
FR2794747B1 (fr) * 1999-06-09 2004-04-16 Hoechst Marion Roussel Inc Nouveaux derives de l'echinocandine, leur procede de preparation et leur application comme anti-fongiques
TWI233805B (en) * 1999-07-01 2005-06-11 Fujisawa Pharmaceutical Co Stabilized pharmaceutical composition in lyophilized form as antifungal agent
AUPR362001A0 (en) * 2001-03-08 2001-04-05 Fujisawa Pharmaceutical Co., Ltd. New compound
CN101861330A (zh) * 2007-10-29 2010-10-13 安斯泰来制药有限公司 多肽化合物
ES2634431T3 (es) * 2009-03-16 2017-09-27 The Governing Council Of The University Of Toronto Moléculas de aminoácidos cíclicos y procedimientos de preparación de las mismas
US8927801B2 (en) * 2009-04-13 2015-01-06 The Procter & Gamble Company Absorbent articles comprising wetness indicators
JP2014088326A (ja) * 2011-02-22 2014-05-15 Astellas Pharma Inc ポリペプチド化合物
CN102512379B (zh) * 2011-12-16 2017-03-08 深圳市健元医药科技有限公司 一种新型棘白菌素类抗真菌药物组合物及其制备方法
CN102627689B (zh) * 2012-03-30 2014-08-06 上海天伟生物制药有限公司 一种环肽类化合物的水合物及其制备方法和用途
CN102786591B (zh) * 2012-08-31 2014-03-12 哈尔滨工业大学 定向诱导合成金属硫蛋白的工艺
WO2017079820A1 (en) 2015-11-11 2017-05-18 Encycle Therapeutics, Inc. CYCLIC PEPTIDES TARGETING α4β7 INTEGRIN
JP7035044B2 (ja) 2016-11-11 2022-03-14 ジーランド ファーマ エー／エス α４β７インテグリンを標的とする環状ペプチド多量体
CA3062385A1 (en) 2017-05-10 2018-11-15 Encycle Therapeutics, Inc. Homodetic cyclic peptides targeting a4s7 1ntegrin
CN112759627B (zh) * 2021-03-12 2021-10-01 河南科技大学 一种抗白色念珠菌多肽及其应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5166135A (en) * 1988-09-12 1992-11-24 Merck & Company, Inc. Method for the control of pneumocystis carinii
GB8925593D0 (en) * 1989-11-13 1990-01-04 Fujisawa Pharmaceutical Co Fr901379 substance and preparation thereof
US5386009A (en) * 1990-03-19 1995-01-31 Merck & Co. Inc. Lipopeptide derivatives
US5330973A (en) * 1990-03-19 1994-07-19 Merck & Co., Inc. Lipopeptide derivatives
US5159059A (en) * 1990-05-29 1992-10-27 Merck & Co., Inc. Process for reduction of certain cyclohexapeptide compounds
FI912873A (fi) * 1990-06-18 1991-12-19 Fujisawa Pharmaceutical Co Ny polypeptidfoerening och foerfarande foer dess framstaellning.
WO1994009033A1 (en) * 1992-10-16 1994-04-28 Merck & Co., Inc. An improved process for cyclohexapeptidyl bisamine compounds

Also Published As

Publication number Publication date
KR100346489B1 (ko) 2002-11-18
US5569646A (en) 1996-10-29
DK0644199T3 (da) 2000-09-18
ES2148254T3 (es) 2000-10-16
EP0644199B1 (en) 2000-07-19
AU6199494A (en) 1994-11-24
CN1100104A (zh) 1995-03-15
CN1057306C (zh) 2000-10-11
US5693750A (en) 1997-12-02
PH30811A (en) 1997-10-17
IL109615A (en) 2000-12-06
GR3034366T3 (en) 2000-12-29
HUT68385A (en) 1995-06-28
DE69425304D1 (de) 2000-08-24
JPH06340693A (ja) 1994-12-13
ATE194846T1 (de) 2000-08-15
AU681119B2 (en) 1997-08-21
DE69425304T2 (de) 2000-12-21
CA2123921A1 (en) 1994-11-18
PT644199E (pt) 2001-01-31
JP3551469B2 (ja) 2004-08-04
IL109615A0 (en) 1994-08-26
RU2164230C2 (ru) 2001-03-20
EP0644199A1 (en) 1995-03-22
HU9401515D0 (en) 1994-08-29

Similar Documents

Publication Publication Date Title
TW301655B (pt)
ES2540810T3 (es) Proceso para preparar compuestos azabicíclicos
RU2351596C2 (ru) Производные n-[гетероарил(пиперидин-2-ил)метил]бензамида и их применение в терапии
WO2022143473A1 (zh) 一种核苷类化合物及其用途
CN106255679B (zh) 用作nav通道抑制剂的杂环化合物及其用途
CN109311854A (zh) 具有仲酰胺官能团的苯并氮杂卓二甲酰胺化合物
CN108699077A (zh) 作为rsv抑制剂的杂环化合物
SU812182A3 (ru) Способ получени 7-метокси-1- ОКСАдЕТиАцЕфАлОСпОРиНОВ или иХСОлЕй
CN102762575A (zh) 多环化合物及其使用方法
CN103906741A (zh) 氨烷基取代的n-噻吩基苯甲酰胺衍生物
CN103957710B (zh) 用于治疗粘膜炎的化合物
CA2965512A1 (en) Trifluoromethyl alcohols as modulators of ror.gamma.t
CN109715167A (zh) 脂质取代的氨基1,2-和1,3-二醇化合物作为tlr2二聚化的调节剂
AU2013305663B2 (en) Benzofurazan anti-amyloid compounds and methods
CN100418525C (zh) 对钙通道α-2-δ亚基具有亲合力的脯氨酸衍生物
CN101454309B (zh) 焦谷氨酸衍生物的合成和用途
CN115403546B (zh) 愈创木烷类倍半萜衍生物及其制药用途
BRPI0615670A2 (pt) composição de liberação prolongada, formulação multiparticulada, e, uso de uma composição e do composto
AU2020361324B2 (en) Novel compound and use thereof in treating autoimmune diseases
CN106687504A (zh) 主链型聚胺
WO1994017058A1 (en) Imidazole compound
CN109071503A (zh) 用于抑制亲环素的化合物及其用途
TW214545B (pt)
WO2007110704A2 (en) Macrolide compositions as therapeutic agent
CN109535060B (zh) 一种刺猬通路抑制剂及其制备方法和应用