TW213901B - - Google Patents

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Publication number
TW213901B
TW213901B TW081110044A TW81110044A TW213901B TW 213901 B TW213901 B TW 213901B TW 081110044 A TW081110044 A TW 081110044A TW 81110044 A TW81110044 A TW 81110044A TW 213901 B TW213901 B TW 213901B
Authority
TW
Taiwan
Prior art keywords
phenyl
gas
page
butyl
cns
Prior art date
Application number
TW081110044A
Other languages
English (en)
Chinese (zh)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of TW213901B publication Critical patent/TW213901B/zh

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06139Dipeptides with the first amino acid being heterocyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16Benzazepines; Hydrogenated benzazepines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
TW081110044A 1992-01-27 1992-12-15 TW213901B (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82567792A 1992-01-27 1992-01-27

Publications (1)

Publication Number Publication Date
TW213901B true TW213901B (fr) 1993-10-01

Family

ID=25244657

Family Applications (1)

Application Number Title Priority Date Filing Date
TW081110044A TW213901B (fr) 1992-01-27 1992-12-15

Country Status (19)

Country Link
EP (1) EP0625145A1 (fr)
JP (1) JPH07503465A (fr)
KR (1) KR950700257A (fr)
CN (1) CN1074903A (fr)
AU (1) AU3276193A (fr)
BR (1) BR9207071A (fr)
CA (1) CA2117367A1 (fr)
CZ (1) CZ391092A3 (fr)
FI (1) FI943513A0 (fr)
HU (1) HUT70496A (fr)
IL (1) IL104472A0 (fr)
MX (1) MX9300409A (fr)
NO (1) NO942775L (fr)
NZ (1) NZ245759A (fr)
RU (1) RU94038063A (fr)
TW (1) TW213901B (fr)
WO (1) WO1993015059A1 (fr)
YU (1) YU4393A (fr)
ZA (1) ZA93582B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2097688A1 (es) * 1993-07-14 1997-04-01 Pfizer Hexahidroazepinonas y tetrahidrobenzazepinonas sustituidas.
CA2168131C (fr) * 1993-07-26 1998-10-06 John A. Lowe, Iii Tetrahydro-1h-benzazepinones renfermant des substituts acides
US5453424A (en) * 1993-11-22 1995-09-26 Merck & Co., Inc. Furanodiazepines
JPH09505597A (ja) * 1993-11-22 1997-06-03 メルク エンド カンパニー インコーポレーテッド 3−アシルアミノベンゾアゼピン類
US5977355A (en) * 1994-10-04 1999-11-02 Pfizer Inc. Processes and intermediates for preparing 3-amino-benzo(b)azepinones
JPH10511928A (ja) 1994-10-14 1998-11-17 グラクソ、ウェルカム、ソシエタ、ペル、アツィオーニ 睡眠障害の治療のためのcck−bレセプター拮抗薬の使用
DE10153348A1 (de) * 2001-10-29 2003-05-08 Gruenenthal Gmbh Substituierte Benzo(b)azepin-2-on-Verbindungen

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0166357A3 (fr) * 1984-06-26 1988-10-26 Merck & Co. Inc. Benzo-lactames condensés et leurs compositions pharmaceutiques
US4767756A (en) * 1987-07-17 1988-08-30 E. R. Squibb & Sons, Inc. 3-substituted benzazepines
EP0322779A3 (fr) * 1987-12-29 1991-05-08 Yoshitomi Pharmaceutical Industries, Ltd. Composés de benzolactame et leur utilisation pharmaceutique
US5206234A (en) * 1990-10-22 1993-04-27 Merck & Co., Inc. Benzolactam analogs as antagonists of cck

Also Published As

Publication number Publication date
JPH07503465A (ja) 1995-04-13
YU4393A (sr) 1996-01-09
EP0625145A1 (fr) 1994-11-23
CN1074903A (zh) 1993-08-04
NO942775L (no) 1994-09-20
MX9300409A (es) 1993-07-01
RU94038063A (ru) 1996-05-27
FI943513A (fi) 1994-07-26
FI943513A0 (fi) 1994-07-26
HUT70496A (en) 1995-10-30
ZA93582B (en) 1994-07-27
HU9402195D0 (en) 1994-09-28
CZ391092A3 (en) 1994-01-19
KR950700257A (ko) 1995-01-16
IL104472A0 (en) 1993-05-13
AU3276193A (en) 1993-09-01
BR9207071A (pt) 1995-12-05
CA2117367A1 (fr) 1993-08-05
NO942775D0 (no) 1994-07-26
WO1993015059A1 (fr) 1993-08-05
NZ245759A (en) 1997-06-24

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