TW213488B - - Google Patents

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Publication number
TW213488B
TW213488B TW080102185A TW80102185A TW213488B TW 213488 B TW213488 B TW 213488B TW 080102185 A TW080102185 A TW 080102185A TW 80102185 A TW80102185 A TW 80102185A TW 213488 B TW213488 B TW 213488B
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TW
Taiwan
Prior art keywords
ala
ser
caa
gin
thr
Prior art date
Application number
TW080102185A
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English (en)
Chinese (zh)
Original Assignee
Ciba Geigy Ag
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Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Application granted granted Critical
Publication of TW213488B publication Critical patent/TW213488B/zh

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/746Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for lactic acid bacteria (Streptococcus; Lactococcus; Lactobacillus; Pediococcus; Enterococcus; Leuconostoc; Propionibacterium; Bifidobacterium; Sporolactobacillus)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/815Protease inhibitors from leeches, e.g. hirudin, eglin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/75Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/853Lactobacillus

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  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
TW080102185A 1990-03-22 1991-03-20 TW213488B (enExample)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909006400A GB9006400D0 (en) 1990-03-22 1990-03-22 Bacterial vectors

Publications (1)

Publication Number Publication Date
TW213488B true TW213488B (enExample) 1993-09-21

Family

ID=10673033

Family Applications (1)

Application Number Title Priority Date Filing Date
TW080102185A TW213488B (enExample) 1990-03-22 1991-03-20

Country Status (22)

Country Link
US (1) US5559007A (enExample)
EP (1) EP0449770B1 (enExample)
JP (1) JPH04211384A (enExample)
KR (1) KR910016930A (enExample)
AR (1) AR245504A1 (enExample)
AT (1) ATE174055T1 (enExample)
AU (1) AU643511B2 (enExample)
BR (1) BR9101137A (enExample)
CA (1) CA2038706A1 (enExample)
DE (1) DE69130544T2 (enExample)
DK (1) DK0449770T3 (enExample)
ES (1) ES2125864T3 (enExample)
FI (1) FI911367L (enExample)
GB (1) GB9006400D0 (enExample)
HU (1) HUT57263A (enExample)
IE (1) IE910948A1 (enExample)
MX (1) MX25027A (enExample)
NO (1) NO911138L (enExample)
NZ (1) NZ237506A (enExample)
PT (1) PT97081B (enExample)
TW (1) TW213488B (enExample)
ZA (1) ZA912114B (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5286361A (en) * 1992-10-19 1994-02-15 Regents Of The University Of California Magnetically attached sputter targets
WO1996032486A1 (en) * 1995-04-11 1996-10-17 Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno Method for the construction of vectors for lactic acid bacteria like lactobacillus such that the bacteria can efficiently express, secrete and display proteins at the surface
GB9521568D0 (en) * 1995-10-20 1995-12-20 Lynxvale Ltd Delivery of biologically active polypeptides
NZ334521A (en) * 1996-09-06 2000-03-27 Bioteknologisk Inst A lactic acid bacterial regulatable expression system
EP1239032A1 (en) * 2001-03-02 2002-09-11 Société des Produits Nestlé S.A. Lactic acid bacteria as agents for treating and preventing allergy
US7780961B2 (en) 2001-05-03 2010-08-24 Actogenix N.V. Self-containing Lactococcus strain
ES2302945T3 (es) 2002-06-19 2008-08-01 Actogenix N.V. Metodos y medios para fomentar la absorcion intestinal.
EP1560935A2 (en) * 2002-11-15 2005-08-10 VIB vzw Self-containing lactobacillus strain
RU2420569C2 (ru) 2005-11-29 2011-06-10 Актогеникс Нв Индукция толерантности к антигенам через слизистую
CA2675115C (en) 2007-01-12 2014-12-09 Actogenix N.V. Lactococcus promoters and uses thereof
BRPI0807857A2 (pt) 2007-01-25 2014-05-27 Actogenix Nv Tratamento de doença imune por meio de distribuição através da mucosa de antígenos.
JP5126879B2 (ja) * 2007-07-13 2013-01-23 独立行政法人海洋研究開発機構 新規dna断片およびそれを含む組換えベクター、それらによって形質転換された形質転換体、ならびにそれらの利用
WO2010034844A1 (en) 2008-09-29 2010-04-01 Actogenix N.V. Reduced colonization of microbes at the mucosa
US9574169B2 (en) 2009-04-30 2017-02-21 Intrexon Actobiotics Nv Cryoprotectants for freeze drying of lactic acid bacteria
EP2275527A1 (en) 2009-07-17 2011-01-19 ActoGeniX NV Animal component-free culture medium for bacterial fermentation
EP2483409B1 (en) 2009-09-29 2017-03-22 Intrexon Actobiotics NV LACTOBACILLUS glyceraldehyde-3-phosphate dehydrogenase PROMOTERS AND USES THEREOF
US20130164380A1 (en) 2010-06-17 2013-06-27 Actogenix Nv Compositions and methods for treating inflammatory conditions
EP3360967B1 (en) 2011-06-01 2020-09-09 Intrexon Actobiotics NV Polycistronic expression system for bacteria
HUE038830T2 (hu) 2011-09-23 2018-11-28 Intrexon Actobiotics Nv Módosított gram-pozitív baktériumok és alkalmazásaik
CA3131722A1 (en) 2011-09-23 2013-03-28 Intrexon Actobiotics Nv Modified gram positive bacteria and uses thereof
EP3402499B1 (en) 2016-01-14 2021-07-21 Intrexon Actobiotics NV Compositions and methods for the treatment of type 1 diabetes
EP3601572A4 (en) * 2017-03-22 2021-01-06 Agency for Science, Technology and Research PROTEIN EXPRESSION CONSTRUCTION AND RELATED PROCESSES
CN116144690A (zh) * 2022-08-23 2023-05-23 江西省科学院微生物研究所(江西省流域生态研究所) 一种大肠杆菌与乳酸菌的穿梭载体pDXA及构建方法与应用
WO2025233675A1 (en) 2024-05-10 2025-11-13 Institut Pasteur Use of talosaminidase to regulate populations of archaeal methanogens in industrial, agricultural and medical settings

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8400687A (nl) 1984-03-02 1985-10-01 Unilever Nv Recombinant plasmiden; recombinant plasmiden bevattende bacterien; werkwijze voor het bereiden of vervaardigen van een zuivelproduct; werkwijze voor het bereiden van een eiwit.
EP0168342B1 (de) 1984-06-14 1991-07-03 Ciba-Geigy Ag Verfahren zur Herstellung von Thrombin-Inhibitoren
NL8503316A (nl) * 1985-11-29 1987-06-16 Stichting Nl I Zuivelonderzoek Werkwijze voor het bereiden van proteinen met behulp van gastheer-organismen, in het bijzonder melkzuurbacterien, welke recombinant dna-plasmiden met een hoge replicon-aktiviteit en een hoge promotor-aktiviteit voor het betreffende proteine-coderende gen bevatten, de van dergelijke recombinant dna-plasmiden voorziene gastheerorganismen, de recombinant dna-plasmiden zelve, de replicon-aktiviteit en promotor-aktiviteit coderende dna-fragmenten, alsmede de verkregen proteinen.
EP0316677A3 (en) 1987-11-13 1990-04-25 Miles Inc. Method for cloning in lactic acid bacteria
NL9000753A (nl) * 1990-03-30 1991-10-16 Nl Zuivelonderzoek Inst Dna-fragment, ten minste coderend voor een deel van het extracellulaire eiwit met een schijnbaar molecuulgewicht van 60 kda van lactococcus lactis stammen zoals de lactococcus lactis ssp. lactis stam mg1363, combinaties hiervan met voor homologe of heterologe eiwitten coderende dna-sequenties alsmede de hiermee verkregen homologe en heterologe eiwitten.

Also Published As

Publication number Publication date
GB9006400D0 (en) 1990-05-23
IE910948A1 (en) 1991-09-25
JPH04211384A (ja) 1992-08-03
FI911367A7 (fi) 1991-09-23
ATE174055T1 (de) 1998-12-15
HU910958D0 (en) 1991-10-28
DE69130544T2 (de) 1999-04-29
NO911138L (no) 1991-09-23
EP0449770B1 (en) 1998-12-02
AR245504A1 (es) 1994-01-31
US5559007A (en) 1996-09-24
DK0449770T3 (da) 1999-06-23
AU7355891A (en) 1991-10-03
MX25027A (es) 1993-12-01
EP0449770A3 (en) 1992-07-01
FI911367A0 (fi) 1991-03-20
AU643511B2 (en) 1993-11-18
DE69130544D1 (de) 1999-01-14
HUT57263A (en) 1991-11-28
NO911138D0 (no) 1991-03-21
ES2125864T3 (es) 1999-03-16
ZA912114B (en) 1992-01-29
PT97081A (pt) 1991-11-29
FI911367L (fi) 1991-09-23
PT97081B (pt) 1998-07-31
KR910016930A (ko) 1991-11-05
BR9101137A (pt) 1991-11-05
EP0449770A2 (en) 1991-10-02
NZ237506A (en) 1992-12-23
CA2038706A1 (en) 1991-09-23

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