DE69130544T2 - Bakterielle Vektoren - Google Patents
Bakterielle VektorenInfo
- Publication number
- DE69130544T2 DE69130544T2 DE69130544T DE69130544T DE69130544T2 DE 69130544 T2 DE69130544 T2 DE 69130544T2 DE 69130544 T DE69130544 T DE 69130544T DE 69130544 T DE69130544 T DE 69130544T DE 69130544 T2 DE69130544 T2 DE 69130544T2
- Authority
- DE
- Germany
- Prior art keywords
- bacterial vectors
- vectors
- bacterial
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/746—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for lactic acid bacteria (Streptococcus; Lactococcus; Lactobacillus; Pediococcus; Enterococcus; Leuconostoc; Propionibacterium; Bifidobacterium; Sporolactobacillus)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/853—Lactobacillus
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB909006400A GB9006400D0 (en) | 1990-03-22 | 1990-03-22 | Bacterial vectors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69130544D1 DE69130544D1 (de) | 1999-01-14 |
| DE69130544T2 true DE69130544T2 (de) | 1999-04-29 |
Family
ID=10673033
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69130544T Expired - Fee Related DE69130544T2 (de) | 1990-03-22 | 1991-03-13 | Bakterielle Vektoren |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US5559007A (de) |
| EP (1) | EP0449770B1 (de) |
| JP (1) | JPH04211384A (de) |
| KR (1) | KR910016930A (de) |
| AR (1) | AR245504A1 (de) |
| AT (1) | ATE174055T1 (de) |
| AU (1) | AU643511B2 (de) |
| BR (1) | BR9101137A (de) |
| CA (1) | CA2038706A1 (de) |
| DE (1) | DE69130544T2 (de) |
| DK (1) | DK0449770T3 (de) |
| ES (1) | ES2125864T3 (de) |
| FI (1) | FI911367A (de) |
| GB (1) | GB9006400D0 (de) |
| HU (1) | HUT57263A (de) |
| IE (1) | IE910948A1 (de) |
| MX (1) | MX25027A (de) |
| NO (1) | NO911138L (de) |
| NZ (1) | NZ237506A (de) |
| PT (1) | PT97081B (de) |
| TW (1) | TW213488B (de) |
| ZA (1) | ZA912114B (de) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5286361A (en) * | 1992-10-19 | 1994-02-15 | Regents Of The University Of California | Magnetically attached sputter targets |
| WO1996032486A1 (en) * | 1995-04-11 | 1996-10-17 | Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno | Method for the construction of vectors for lactic acid bacteria like lactobacillus such that the bacteria can efficiently express, secrete and display proteins at the surface |
| GB9521568D0 (en) * | 1995-10-20 | 1995-12-20 | Lynxvale Ltd | Delivery of biologically active polypeptides |
| DE69716622T2 (de) * | 1996-09-06 | 2003-07-10 | Bioteknologisk Inst Hoersholm | Milchsäurebakterielles regulierbares expressionssystem |
| EP1239032A1 (de) * | 2001-03-02 | 2002-09-11 | Société des Produits Nestlé S.A. | Milchsäurebakterien als Mitteln zur Behandlung und Vorbeugung von Allergie |
| US7780961B2 (en) | 2001-05-03 | 2010-08-24 | Actogenix N.V. | Self-containing Lactococcus strain |
| ES2302945T3 (es) | 2002-06-19 | 2008-08-01 | Actogenix N.V. | Metodos y medios para fomentar la absorcion intestinal. |
| WO2004046346A2 (en) * | 2002-11-15 | 2004-06-03 | Vib Vzw | Self-containing lactobacillus strain |
| DK2119450T3 (da) | 2005-11-29 | 2013-05-06 | Actogenix Nv | Induktion af mucosal tolerance over for pankreatisk ø-beta-celle-autoantigener |
| CA2675115C (en) | 2007-01-12 | 2014-12-09 | Actogenix N.V. | Lactococcus promoters and uses thereof |
| US20100104601A1 (en) | 2007-01-25 | 2010-04-29 | Pieter Rottiers | Treatment of immune disease by mucosal delivery of antigents using genetically modified lactobacillus |
| JP5126879B2 (ja) * | 2007-07-13 | 2013-01-23 | 独立行政法人海洋研究開発機構 | 新規ｄｎａ断片およびそれを含む組換えベクター、それらによって形質転換された形質転換体、ならびにそれらの利用 |
| JP2012504116A (ja) | 2008-09-29 | 2012-02-16 | アクトジェニックス・エヌブイ | 粘膜での微生物のコロニー形成の低減 |
| DK2424972T3 (da) | 2009-04-30 | 2013-10-14 | Actogenix Nv | Kryobeskyttende midler til frysetørring af mælkesyrebakterier |
| EP2275527A1 (de) | 2009-07-17 | 2011-01-19 | ActoGeniX NV | Kulturmedium zur Fermentation von Bakterien welches frei von tierischen Bestandteilen ist |
| WO2011039137A1 (en) | 2009-09-29 | 2011-04-07 | Actogenix N.V. | Lactobacillus and streptococcus promoters and uses thereof |
| WO2011160062A2 (en) | 2010-06-17 | 2011-12-22 | The Usa As Represented By The Secretary, National Institutes Of Health | Compositions and methods for treating inflammatory conditions |
| KR102066292B1 (ko) | 2011-06-01 | 2020-01-14 | 인트랙슨 액토바이오틱스 엔.브이. | 박테리아용 폴리시스트론 발현 시스템 |
| ES2676707T3 (es) | 2011-09-23 | 2018-07-24 | Intrexon Actobiotics Nv | Bacterias gram positivas modificadas y usos de las mismas |
| US9347036B2 (en) | 2011-09-23 | 2016-05-24 | Intrexon Actobiotics Nv | Modified gram positive bacteria and uses thereof |
| US10905727B2 (en) | 2016-01-14 | 2021-02-02 | Intrexon Actobiotics N.V. | Compositions and methods for the treatment of type 1 diabetes |
| US20200095566A1 (en) * | 2017-03-22 | 2020-03-26 | Agency For Science, Technology And Research | Protein Expression Construct and Methods Thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL8400687A (nl) | 1984-03-02 | 1985-10-01 | Unilever Nv | Recombinant plasmiden; recombinant plasmiden bevattende bacterien; werkwijze voor het bereiden of vervaardigen van een zuivelproduct; werkwijze voor het bereiden van een eiwit. |
| EP0168342B1 (de) | 1984-06-14 | 1991-07-03 | Ciba-Geigy Ag | Verfahren zur Herstellung von Thrombin-Inhibitoren |
| NL8503316A (nl) * | 1985-11-29 | 1987-06-16 | Stichting Nl I Zuivelonderzoek | Werkwijze voor het bereiden van proteinen met behulp van gastheer-organismen, in het bijzonder melkzuurbacterien, welke recombinant dna-plasmiden met een hoge replicon-aktiviteit en een hoge promotor-aktiviteit voor het betreffende proteine-coderende gen bevatten, de van dergelijke recombinant dna-plasmiden voorziene gastheerorganismen, de recombinant dna-plasmiden zelve, de replicon-aktiviteit en promotor-aktiviteit coderende dna-fragmenten, alsmede de verkregen proteinen. |
| EP0316677A3 (de) | 1987-11-13 | 1990-04-25 | Miles Inc. | Verfahren zur Klonierung in Milchsäurebakterien |
| NL9000753A (nl) * | 1990-03-30 | 1991-10-16 | Nl Zuivelonderzoek Inst | Dna-fragment, ten minste coderend voor een deel van het extracellulaire eiwit met een schijnbaar molecuulgewicht van 60 kda van lactococcus lactis stammen zoals de lactococcus lactis ssp. lactis stam mg1363, combinaties hiervan met voor homologe of heterologe eiwitten coderende dna-sequenties alsmede de hiermee verkregen homologe en heterologe eiwitten. |
-
1990
- 1990-03-22 GB GB909006400A patent/GB9006400D0/en active Pending
-
1991
- 1991-03-13 DE DE69130544T patent/DE69130544T2/de not_active Expired - Fee Related
- 1991-03-13 AT AT91810167T patent/ATE174055T1/de not_active IP Right Cessation
- 1991-03-13 ES ES91810167T patent/ES2125864T3/es not_active Expired - Lifetime
- 1991-03-13 EP EP91810167A patent/EP0449770B1/de not_active Expired - Lifetime
- 1991-03-13 DK DK91810167T patent/DK0449770T3/da active
- 1991-03-15 AU AU73558/91A patent/AU643511B2/en not_active Ceased
- 1991-03-20 FI FI911367A patent/FI911367A/fi not_active Application Discontinuation
- 1991-03-20 CA CA002038706A patent/CA2038706A1/en not_active Abandoned
- 1991-03-20 TW TW080102185A patent/TW213488B/zh active
- 1991-03-20 NZ NZ237506A patent/NZ237506A/en unknown
- 1991-03-20 JP JP3056889A patent/JPH04211384A/ja active Pending
- 1991-03-20 PT PT97081A patent/PT97081B/pt not_active IP Right Cessation
- 1991-03-21 IE IE094891A patent/IE910948A1/en unknown
- 1991-03-21 ZA ZA912114A patent/ZA912114B/xx unknown
- 1991-03-21 HU HU91958A patent/HUT57263A/hu unknown
- 1991-03-21 KR KR1019910004439A patent/KR910016930A/ko not_active Application Discontinuation
- 1991-03-21 NO NO91911138A patent/NO911138L/no unknown
- 1991-03-22 MX MX2502791A patent/MX25027A/es unknown
- 1991-03-22 AR AR91319296A patent/AR245504A1/es active
- 1991-03-22 BR BR919101137A patent/BR9101137A/pt unknown
-
1994
- 1994-01-21 US US08/186,222 patent/US5559007A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AR245504A1 (es) | 1994-01-31 |
| ATE174055T1 (de) | 1998-12-15 |
| PT97081A (pt) | 1991-11-29 |
| EP0449770A3 (en) | 1992-07-01 |
| DE69130544D1 (de) | 1999-01-14 |
| ES2125864T3 (es) | 1999-03-16 |
| AU643511B2 (en) | 1993-11-18 |
| FI911367A0 (fi) | 1991-03-20 |
| IE910948A1 (en) | 1991-09-25 |
| NZ237506A (en) | 1992-12-23 |
| NO911138D0 (no) | 1991-03-21 |
| NO911138L (no) | 1991-09-23 |
| FI911367A (fi) | 1991-09-23 |
| EP0449770B1 (de) | 1998-12-02 |
| HU910958D0 (en) | 1991-10-28 |
| BR9101137A (pt) | 1991-11-05 |
| DK0449770T3 (da) | 1999-06-23 |
| AU7355891A (en) | 1991-10-03 |
| US5559007A (en) | 1996-09-24 |
| CA2038706A1 (en) | 1991-09-23 |
| KR910016930A (ko) | 1991-11-05 |
| PT97081B (pt) | 1998-07-31 |
| HUT57263A (en) | 1991-11-28 |
| ZA912114B (en) | 1992-01-29 |
| TW213488B (de) | 1993-09-21 |
| EP0449770A2 (de) | 1991-10-02 |
| MX25027A (es) | 1993-12-01 |
| GB9006400D0 (en) | 1990-05-23 |
| JPH04211384A (ja) | 1992-08-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |