NO911138L - Bakterielle vektorer. - Google Patents

Bakterielle vektorer.

Info

Publication number
NO911138L
NO911138L NO91911138A NO911138A NO911138L NO 911138 L NO911138 L NO 911138L NO 91911138 A NO91911138 A NO 91911138A NO 911138 A NO911138 A NO 911138A NO 911138 L NO911138 L NO 911138L
Authority
NO
Norway
Prior art keywords
spee
lactococcus
new
msp
dna
Prior art date
Application number
NO91911138A
Other languages
English (en)
Other versions
NO911138D0 (no
Inventor
Bruno Suri
Albert Schmitz
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of NO911138D0 publication Critical patent/NO911138D0/no
Publication of NO911138L publication Critical patent/NO911138L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/746—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for lactic acid bacteria (Streptococcus; Lactococcus; Lactobacillus; Pediococcus; Enterococcus; Leuconostoc; Propionibacterium; Bifidobacterium; Sporolactobacillus)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/853—Lactobacillus

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Nye DNA molekyler som omfatter multifunksjonelle replikasjonsorlgoer og/eller en DNA sekvens kodende for det mest tilstedeværende proteinet l supernatanten av kulturer av Lactococcus spee., betegnet hovedutsklll- elsesprodukt (MSP), på grunn av dets signalpeptld og/eller promoteren til MSP genet, er tllvelebragt. De nye DNA molekylene blir anvendt for fremstilling av nye shyttelvektorer for kloning av DNA l minst E.coli og Lactococcus spee. eller nye vektorer for ekspresjon av homologe eller heterologe gener og produksjon av utskilte genprodukter l gram-positlve bakterier såsom Lactococcus spee. og Bacllolus spec.
NO91911138A 1990-03-22 1991-03-21 Bakterielle vektorer. NO911138L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909006400A GB9006400D0 (en) 1990-03-22 1990-03-22 Bacterial vectors

Publications (2)

Publication Number Publication Date
NO911138D0 NO911138D0 (no) 1991-03-21
NO911138L true NO911138L (no) 1991-09-23

Family

ID=10673033

Family Applications (1)

Application Number Title Priority Date Filing Date
NO91911138A NO911138L (no) 1990-03-22 1991-03-21 Bakterielle vektorer.

Country Status (22)

Country Link
US (1) US5559007A (no)
EP (1) EP0449770B1 (no)
JP (1) JPH04211384A (no)
KR (1) KR910016930A (no)
AR (1) AR245504A1 (no)
AT (1) ATE174055T1 (no)
AU (1) AU643511B2 (no)
BR (1) BR9101137A (no)
CA (1) CA2038706A1 (no)
DE (1) DE69130544T2 (no)
DK (1) DK0449770T3 (no)
ES (1) ES2125864T3 (no)
FI (1) FI911367A (no)
GB (1) GB9006400D0 (no)
HU (1) HUT57263A (no)
IE (1) IE910948A1 (no)
MX (1) MX25027A (no)
NO (1) NO911138L (no)
NZ (1) NZ237506A (no)
PT (1) PT97081B (no)
TW (1) TW213488B (no)
ZA (1) ZA912114B (no)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5286361A (en) * 1992-10-19 1994-02-15 Regents Of The University Of California Magnetically attached sputter targets
WO1996032486A1 (en) * 1995-04-11 1996-10-17 Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno Method for the construction of vectors for lactic acid bacteria like lactobacillus such that the bacteria can efficiently express, secrete and display proteins at the surface
GB9521568D0 (en) * 1995-10-20 1995-12-20 Lynxvale Ltd Delivery of biologically active polypeptides
DE69716622T2 (de) * 1996-09-06 2003-07-10 Bioteknologisk Inst Hoersholm Milchsäurebakterielles regulierbares expressionssystem
EP1239032A1 (en) * 2001-03-02 2002-09-11 Société des Produits Nestlé S.A. Lactic acid bacteria as agents for treating and preventing allergy
US7780961B2 (en) 2001-05-03 2010-08-24 Actogenix N.V. Self-containing Lactococcus strain
ES2302945T3 (es) 2002-06-19 2008-08-01 Actogenix N.V. Metodos y medios para fomentar la absorcion intestinal.
WO2004046346A2 (en) * 2002-11-15 2004-06-03 Vib Vzw Self-containing lactobacillus strain
DK2119450T3 (da) 2005-11-29 2013-05-06 Actogenix Nv Induktion af mucosal tolerance over for pankreatisk ø-beta-celle-autoantigener
CA2675115C (en) 2007-01-12 2014-12-09 Actogenix N.V. Lactococcus promoters and uses thereof
US20100104601A1 (en) 2007-01-25 2010-04-29 Pieter Rottiers Treatment of immune disease by mucosal delivery of antigents using genetically modified lactobacillus
JP5126879B2 (ja) * 2007-07-13 2013-01-23 独立行政法人海洋研究開発機構 新規ｄｎａ断片およびそれを含む組換えベクター、それらによって形質転換された形質転換体、ならびにそれらの利用
JP2012504116A (ja) 2008-09-29 2012-02-16 アクトジェニックス・エヌブイ 粘膜での微生物のコロニー形成の低減
DK2424972T3 (da) 2009-04-30 2013-10-14 Actogenix Nv Kryobeskyttende midler til frysetørring af mælkesyrebakterier
EP2275527A1 (en) 2009-07-17 2011-01-19 ActoGeniX NV Animal component-free culture medium for bacterial fermentation
WO2011039137A1 (en) 2009-09-29 2011-04-07 Actogenix N.V. Lactobacillus and streptococcus promoters and uses thereof
WO2011160062A2 (en) 2010-06-17 2011-12-22 The Usa As Represented By The Secretary, National Institutes Of Health Compositions and methods for treating inflammatory conditions
KR102066292B1 (ko) 2011-06-01 2020-01-14 인트랙슨 액토바이오틱스 엔.브이. 박테리아용 폴리시스트론 발현 시스템
ES2676707T3 (es) 2011-09-23 2018-07-24 Intrexon Actobiotics Nv Bacterias gram positivas modificadas y usos de las mismas
US9347036B2 (en) 2011-09-23 2016-05-24 Intrexon Actobiotics Nv Modified gram positive bacteria and uses thereof
US10905727B2 (en) 2016-01-14 2021-02-02 Intrexon Actobiotics N.V. Compositions and methods for the treatment of type 1 diabetes
US20200095566A1 (en) * 2017-03-22 2020-03-26 Agency For Science, Technology And Research Protein Expression Construct and Methods Thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8400687A (nl) 1984-03-02 1985-10-01 Unilever Nv Recombinant plasmiden; recombinant plasmiden bevattende bacterien; werkwijze voor het bereiden of vervaardigen van een zuivelproduct; werkwijze voor het bereiden van een eiwit.
EP0168342B1 (de) 1984-06-14 1991-07-03 Ciba-Geigy Ag Verfahren zur Herstellung von Thrombin-Inhibitoren
NL8503316A (nl) * 1985-11-29 1987-06-16 Stichting Nl I Zuivelonderzoek Werkwijze voor het bereiden van proteinen met behulp van gastheer-organismen, in het bijzonder melkzuurbacterien, welke recombinant dna-plasmiden met een hoge replicon-aktiviteit en een hoge promotor-aktiviteit voor het betreffende proteine-coderende gen bevatten, de van dergelijke recombinant dna-plasmiden voorziene gastheerorganismen, de recombinant dna-plasmiden zelve, de replicon-aktiviteit en promotor-aktiviteit coderende dna-fragmenten, alsmede de verkregen proteinen.
EP0316677A3 (en) 1987-11-13 1990-04-25 Miles Inc. Method for cloning in lactic acid bacteria
NL9000753A (nl) * 1990-03-30 1991-10-16 Nl Zuivelonderzoek Inst Dna-fragment, ten minste coderend voor een deel van het extracellulaire eiwit met een schijnbaar molecuulgewicht van 60 kda van lactococcus lactis stammen zoals de lactococcus lactis ssp. lactis stam mg1363, combinaties hiervan met voor homologe of heterologe eiwitten coderende dna-sequenties alsmede de hiermee verkregen homologe en heterologe eiwitten.

Also Published As

Publication number Publication date
AR245504A1 (es) 1994-01-31
ATE174055T1 (de) 1998-12-15
PT97081A (pt) 1991-11-29
EP0449770A3 (en) 1992-07-01
DE69130544D1 (de) 1999-01-14
ES2125864T3 (es) 1999-03-16
AU643511B2 (en) 1993-11-18
FI911367A0 (fi) 1991-03-20
IE910948A1 (en) 1991-09-25
NZ237506A (en) 1992-12-23
NO911138D0 (no) 1991-03-21
FI911367A (fi) 1991-09-23
EP0449770B1 (en) 1998-12-02
HU910958D0 (en) 1991-10-28
BR9101137A (pt) 1991-11-05
DK0449770T3 (da) 1999-06-23
AU7355891A (en) 1991-10-03
US5559007A (en) 1996-09-24
CA2038706A1 (en) 1991-09-23
KR910016930A (ko) 1991-11-05
PT97081B (pt) 1998-07-31
DE69130544T2 (de) 1999-04-29
HUT57263A (en) 1991-11-28
ZA912114B (en) 1992-01-29
TW213488B (no) 1993-09-21
EP0449770A2 (en) 1991-10-02
MX25027A (es) 1993-12-01
GB9006400D0 (en) 1990-05-23
JPH04211384A (ja) 1992-08-03

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