TW213456B - - Google Patents
Download PDFInfo
- Publication number
- TW213456B TW213456B TW081108272A TW81108272A TW213456B TW 213456 B TW213456 B TW 213456B TW 081108272 A TW081108272 A TW 081108272A TW 81108272 A TW81108272 A TW 81108272A TW 213456 B TW213456 B TW 213456B
- Authority
- TW
- Taiwan
- Prior art keywords
- shows
- compound
- phenyl
- ministry
- please read
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/08—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing alicyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
- C07C255/11—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound oxygen atoms bound to the same saturated acyclic carbon skeleton
- C07C255/13—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound oxygen atoms bound to the same saturated acyclic carbon skeleton containing cyano groups and etherified hydroxy groups bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US82467892A | 1992-01-23 | 1992-01-23 | |
| US89005592A | 1992-05-28 | 1992-05-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW213456B true TW213456B (fr) | 1993-09-21 |
Family
ID=27124835
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW081108272A TW213456B (fr) | 1992-01-23 | 1992-10-17 |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US5550152A (fr) |
| EP (1) | EP0623122B1 (fr) |
| JP (1) | JP2813464B2 (fr) |
| KR (1) | KR950700274A (fr) |
| CN (1) | CN1074681A (fr) |
| AP (1) | AP385A (fr) |
| AT (1) | ATE149493T1 (fr) |
| AU (1) | AU2773392A (fr) |
| BG (1) | BG98873A (fr) |
| BR (1) | BR9207064A (fr) |
| CA (1) | CA2117349C (fr) |
| CZ (1) | CZ395492A3 (fr) |
| DE (1) | DE69217998T2 (fr) |
| DK (1) | DK0623122T3 (fr) |
| ES (1) | ES2098547T3 (fr) |
| FI (1) | FI943473A (fr) |
| GR (1) | GR3022999T3 (fr) |
| HU (1) | HUT67929A (fr) |
| IL (1) | IL104421A0 (fr) |
| IS (1) | IS3968A (fr) |
| MX (1) | MX9300313A (fr) |
| NO (1) | NO942758D0 (fr) |
| OA (1) | OA10713A (fr) |
| PT (1) | PT101182A (fr) |
| TW (1) | TW213456B (fr) |
| UY (1) | UY23537A1 (fr) |
| WO (1) | WO1993015066A1 (fr) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX9300312A (es) * | 1992-01-23 | 1993-07-31 | Pfizer | Antagonistas benzopiranicos y relacionado de ltb. |
| CA2202056A1 (fr) * | 1994-10-13 | 1996-04-25 | Mark A. Dombroski | Composes de benzopyranne et composes benzo-fusionnes, leur preparation et leur utilisation comme antagonistes du leucotriene b4' (ltb4) |
| MX9702731A (es) * | 1994-10-13 | 1997-06-28 | Pfizer | Compuestos de benzopirano y benzo fusionados, composiciones que los contienen y uso de los mismos. |
| SK31399A3 (en) * | 1996-09-16 | 2000-05-16 | Pfizer | Processes and intermediates for preparing substituted chromanol derivatives |
| US6416733B1 (en) | 1996-10-07 | 2002-07-09 | Bristol-Myers Squibb Pharma Company | Radiopharmaceuticals for imaging infection and inflammation |
| EP0836850A3 (fr) * | 1996-10-17 | 2000-11-29 | Pfizer Inc. | Méthode pour prévenir le rejet d'allogreffes |
| EP0963755A3 (fr) * | 1998-04-16 | 2001-03-14 | Pfizer Products Inc. | Utilisation des benzopyranes pour la prévention de rejets de graiffes |
| JP2004512382A (ja) | 2000-11-03 | 2004-04-22 | ブリストル−マイヤーズ・スクイブ・ファーマ・カンパニー | 心臓灌流および心臓炎症の２核種同時イメージング |
| US6958156B2 (en) * | 2000-12-15 | 2005-10-25 | Vyrex Corporation | Isoflavone derivatives |
| US6541613B2 (en) * | 2000-12-15 | 2003-04-01 | Uyrex Corporation | Isoflavone derivatives |
| CA2433516A1 (fr) * | 2001-01-30 | 2002-08-08 | Keith Michael Devries | Procedes de preparation d'acides chromanylbenzoiques |
| CA2574627A1 (fr) * | 2004-07-22 | 2006-02-02 | Pharmacia Corporation | Compositions pour le traitement anti-inflammatoire et anti-douleur au moyen d'une combinaison d'un inhibiteur selectif cox-2 et d'un antagoniste recepteur de ltb<sb>4</sb> |
| KR101107800B1 (ko) * | 2006-10-31 | 2012-01-25 | 화이자 프로덕츠 인코포레이티드 | 무기질코르티코이드 수용체 길항제로서의 피라졸린 화합물 |
| CN104710438B (zh) * | 2013-12-11 | 2019-11-29 | 中国科学院上海药物研究所 | 促进iPS细胞产生的螺环类化合物及其制备方法和用途 |
| JP6590224B2 (ja) * | 2014-11-11 | 2019-10-16 | 学校法人順天堂 | 加齢黄斑変性症予防又は治療剤 |
| WO2017040963A1 (fr) | 2015-09-03 | 2017-03-09 | Forma Therapeutics, Inc. | Inhibiteurs de hdac8 bicyclique [6,6] fusionnée |
| US20190382363A1 (en) | 2015-11-30 | 2019-12-19 | Merck Sharp & Dohme Corp. | Aryl sulfonamides as blt1 antagonists |
| US10336733B2 (en) | 2015-11-30 | 2019-07-02 | Merk Sharp & Dohme Corp. | Aryl acylsulfonamides as BLT1 antagonists |
| US10450309B2 (en) | 2015-11-30 | 2019-10-22 | Merch Sharp & Dohme Corp. | Aryl sulfonamides as BLT1 antagonists |
| EP3383389B1 (fr) | 2015-11-30 | 2021-04-28 | Merck Sharp & Dohme Corp. | Utilisation d'arylacylsulfonamides en tant qu'antagonistes de blt1 |
| CN109289091B (zh) * | 2018-10-09 | 2021-04-13 | 温州医科大学附属第一医院 | 一种用于装载骨髓间充质干细胞的复合支架及其制备方法 |
| CN111647003B (zh) * | 2020-06-08 | 2022-06-21 | 中国科学院昆明植物研究所 | 三环氧六氢色酮a及其药物组合物和其应用 |
| CN111671745A (zh) * | 2020-07-29 | 2020-09-18 | 北京大学 | 化合物在治疗溃疡性结肠炎药物制备中的应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4565882A (en) * | 1984-01-06 | 1986-01-21 | G. D. Searle & Co. | Substituted dihydrobenzopyran-2-carboxylates |
| CA1320490C (fr) * | 1987-01-12 | 1993-07-20 | Darrel M. Gapinski | Agents antiinflammatoires |
| US4889871A (en) * | 1987-05-29 | 1989-12-26 | G. D. Searle & Co. | Alkoxy-substituted dihydrobenzopyran-2-carboxylate derivatives |
| US5059609A (en) * | 1987-10-19 | 1991-10-22 | Pfizer Inc. | Substituted tetralins, chromans and related compounds in the treatment of asthma, arthritis and related diseases |
| WO1990015801A1 (fr) * | 1989-06-22 | 1990-12-27 | Pfizer Inc. | Sulfamides substitues et composes apparentes dans le traitement de l'asthme, de l'arthrite et des maladies apparentees |
-
1992
- 1992-10-13 WO PCT/US1992/008555 patent/WO1993015066A1/fr active IP Right Grant
- 1992-10-13 US US08/256,809 patent/US5550152A/en not_active Expired - Lifetime
- 1992-10-13 AT AT92921463T patent/ATE149493T1/de not_active IP Right Cessation
- 1992-10-13 CA CA002117349A patent/CA2117349C/fr not_active Expired - Lifetime
- 1992-10-13 DE DE69217998T patent/DE69217998T2/de not_active Expired - Lifetime
- 1992-10-13 BR BR9207064A patent/BR9207064A/pt not_active Application Discontinuation
- 1992-10-13 CZ CS923954A patent/CZ395492A3/cs unknown
- 1992-10-13 HU HU9402163A patent/HUT67929A/hu unknown
- 1992-10-13 AU AU27733/92A patent/AU2773392A/en not_active Abandoned
- 1992-10-13 DK DK92921463.3T patent/DK0623122T3/da active
- 1992-10-13 JP JP5513182A patent/JP2813464B2/ja not_active Expired - Fee Related
- 1992-10-13 EP EP92921463A patent/EP0623122B1/fr not_active Expired - Lifetime
- 1992-10-13 ES ES92921463T patent/ES2098547T3/es not_active Expired - Lifetime
- 1992-10-17 TW TW081108272A patent/TW213456B/zh active
- 1992-11-10 AP APAP/P/1992/000441A patent/AP385A/en active
-
1993
- 1993-01-18 UY UY23537A patent/UY23537A1/es unknown
- 1993-01-18 IL IL104421A patent/IL104421A0/xx unknown
- 1993-01-19 IS IS3968A patent/IS3968A/is unknown
- 1993-01-20 CN CN93100695A patent/CN1074681A/zh active Pending
- 1993-01-22 MX MX9300313A patent/MX9300313A/es unknown
- 1993-01-22 PT PT101182A patent/PT101182A/pt not_active Application Discontinuation
-
1994
- 1994-06-24 BG BG98873A patent/BG98873A/xx unknown
- 1994-07-22 FI FI943473A patent/FI943473A/fi unknown
- 1994-07-22 OA OA60544A patent/OA10713A/en unknown
- 1994-07-22 NO NO942758A patent/NO942758D0/no unknown
- 1994-07-23 KR KR1019940702540A patent/KR950700274A/ko not_active Application Discontinuation
-
1997
- 1997-04-01 GR GR970400673T patent/GR3022999T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL104421A0 (en) | 1993-05-13 |
| HUT67929A (en) | 1995-05-29 |
| ES2098547T3 (es) | 1997-05-01 |
| US5550152A (en) | 1996-08-27 |
| AP9200441A0 (en) | 1993-01-31 |
| MX9300313A (es) | 1994-06-30 |
| OA10713A (en) | 2002-12-04 |
| FI943473A0 (fi) | 1994-07-22 |
| FI943473A (fi) | 1994-07-22 |
| CN1074681A (zh) | 1993-07-28 |
| IS3968A (is) | 1993-07-24 |
| CA2117349A1 (fr) | 1993-08-05 |
| UY23537A1 (es) | 1993-06-28 |
| DE69217998D1 (de) | 1997-04-10 |
| ATE149493T1 (de) | 1997-03-15 |
| CA2117349C (fr) | 2000-02-29 |
| AU2773392A (en) | 1993-09-01 |
| BR9207064A (pt) | 1995-12-19 |
| WO1993015066A1 (fr) | 1993-08-05 |
| JPH07503464A (ja) | 1995-04-13 |
| AP385A (en) | 1995-05-15 |
| HU9402163D0 (en) | 1994-09-28 |
| KR950700274A (ko) | 1995-01-16 |
| JP2813464B2 (ja) | 1998-10-22 |
| GR3022999T3 (en) | 1997-07-30 |
| CZ395492A3 (en) | 1994-03-16 |
| DE69217998T2 (de) | 1997-06-12 |
| NO942758L (no) | 1994-07-22 |
| EP0623122A1 (fr) | 1994-11-09 |
| BG98873A (en) | 1995-03-31 |
| EP0623122B1 (fr) | 1997-03-05 |
| NO942758D0 (no) | 1994-07-22 |
| DK0623122T3 (da) | 1997-04-21 |
| PT101182A (pt) | 1994-03-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TW213456B (fr) | ||
| TW304941B (fr) | ||
| EP1040103B1 (fr) | Derive d'anilide, sa preparation et son utilisation | |
| WO2010150837A1 (fr) | Dérivé de l'indoline | |
| CA2024258A1 (fr) | Derives heterocycliques | |
| CA2472776C (fr) | Procede de preparation d'inhibiteurs de reductase hmg-coa | |
| CN102630226A (zh) | 恩替卡韦的合成方法及其中间体化合物 | |
| WO2007091570A1 (fr) | Inhibiteur de liaison de sphingosine-1-phosphate | |
| WO2003070686A1 (fr) | Derive de l'acide phenylalcanoyle substitue et son utilisation | |
| TWI482622B (zh) | Shrinkage pyridine compounds | |
| TWI249533B (en) | Pyridazin-3-one derivatives and medicines containing the same | |
| OA11456A (en) | Benzopyran and related LTB4 antagonists. | |
| CN113620931A (zh) | 一种雄激素受体抑制剂及其用途 | |
| KR20140017207A (ko) | 로수바스타틴 이소프로필 아민염, 이의 제조 방법 및 이를 이용한 로수바스타틴 헤미칼슘염의 제조방법 | |
| KR20070010794A (ko) | 광학적으로 순수한 (ｓ)-3-히드록시 피롤리딘의 제조방법 | |
| JPH05310700A (ja) | 縮合ピリジン系メバロノラクトン中間体及びその製法 | |
| JPH09502713A (ja) | Ｈｉｖおよび他のレトロウイルス病を治療するのに有用な置換テトロン酸 | |
| JPH01221380A (ja) | ２，３−ジアシルオキシ−４−ヒドロキシ−トペンタナールおよびその製造方法 | |
| JPH06312989A (ja) | （１ｒｓ，２ｒｓ，４ｓｒ）−２−（６−クロロ−３−ピリジル）−７−アザビシクロ［２．２．１］ヘプタンの製造方法 | |
| WO2014051077A1 (fr) | Procédé de production de composé hétérocyclique contenant de l'azote de pureté élevée | |
| JP6768065B2 (ja) | ベンゾピラン誘導体の精製方法、ベンゾピラン誘導体の結晶形およびベンゾピラン誘導体の結晶形の製造方法 | |
| EP3071550B1 (fr) | Procédé de préparation de composés indéno cycliques fusionnés | |
| WO2015002038A1 (fr) | Nouveau dérivé de phénylnaphtol | |
| JP3869530B2 (ja) | ビフェニル誘導体の製造法 | |
| WO2001072704A1 (fr) | DERIVES AZETODINONE, PROCEDE DE PREPARATION DE CEUX-CI ET PROCEDE DE PRODUCTION DE 1-β-ALKYLE AZETODINONE AU MOYEN DESDITS DERIVES |