TW202038957A - 抗體-藥物結合物與激酶抑制劑之組合 - Google Patents
抗體-藥物結合物與激酶抑制劑之組合 Download PDFInfo
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- TW202038957A TW202038957A TW108147081A TW108147081A TW202038957A TW 202038957 A TW202038957 A TW 202038957A TW 108147081 A TW108147081 A TW 108147081A TW 108147081 A TW108147081 A TW 108147081A TW 202038957 A TW202038957 A TW 202038957A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
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- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2018240049 | 2018-12-21 | ||
| JP2018-240049 | 2018-12-21 | ||
| JP2019085338 | 2019-04-26 | ||
| JP2019-085338 | 2019-04-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW202038957A true TW202038957A (zh) | 2020-11-01 |
Family
ID=71101395
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW108147081A TW202038957A (zh) | 2018-12-21 | 2019-12-20 | 抗體-藥物結合物與激酶抑制劑之組合 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20220040324A1 (https=) |
| EP (1) | EP3903828A4 (https=) |
| JP (2) | JPWO2020130125A1 (https=) |
| KR (1) | KR20210107069A (https=) |
| CN (1) | CN113195000A (https=) |
| AU (1) | AU2019407426A1 (https=) |
| BR (1) | BR112021011894A2 (https=) |
| CA (1) | CA3124330A1 (https=) |
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| KR20140096571A (ko) | 2013-01-28 | 2014-08-06 | 한미약품 주식회사 | 1-(4-(4-(3,4-디클로로-2-플루오로페닐아미노)-7-메톡시퀴나졸린-6-일옥시)피페리딘-1-일)프로프-2-엔-1-온의 제조방법 |
| MX2015009952A (es) | 2013-02-08 | 2015-10-05 | Celgene Avilomics Res Inc | Inhibidores de cinasas reguladas por señales extracelulares (erk) y sus usos. |
| MX2015011438A (es) | 2013-03-13 | 2016-02-03 | Hoffmann La Roche | Procedimiento para preparar compuestos benzoxazepina. |
| TWI731317B (zh) | 2013-12-10 | 2021-06-21 | 美商健臻公司 | 原肌球蛋白相關之激酶(trk)抑制劑 |
| AU2014371934B2 (en) * | 2013-12-25 | 2020-01-23 | Daiichi Sankyo Company, Limited | Anti-TROP2 antibody-drug conjugate |
| IL310627B2 (en) * | 2014-01-31 | 2026-04-01 | Daiichi Sankyo Co Ltd | Anti-HER2 antibody-drug conjugates, compositions containing them and uses thereof |
| JP2017114763A (ja) | 2014-03-26 | 2017-06-29 | 第一三共株式会社 | 抗cd98抗体−薬物コンジュゲート |
| KR102445502B1 (ko) * | 2014-04-10 | 2022-09-21 | 다이이찌 산쿄 가부시키가이샤 | 항her3 항체-약물 콘주게이트 |
| EP3130608B1 (en) | 2014-04-10 | 2019-09-04 | Daiichi Sankyo Co., Ltd. | (anti-her2 antibody)-drug conjugate |
| TWI704151B (zh) | 2014-12-22 | 2020-09-11 | 美商美國禮來大藥廠 | Erk抑制劑 |
| KR102608921B1 (ko) | 2015-05-18 | 2023-12-01 | 스미토모 파마 온콜로지, 인크. | 생체 이용률이 증가된 알보시딥 프로드러그 |
| CN116059395A (zh) | 2015-06-29 | 2023-05-05 | 第一三共株式会社 | 用于选择性制造抗体-药物缀合物的方法 |
| AU2016287463B2 (en) | 2015-07-02 | 2020-07-02 | F. Hoffmann-La Roche Ag | Benzoxazepin oxazolidinone compounds and methods of use |
| PT3497103T (pt) | 2016-08-15 | 2021-06-17 | Pfizer | Inibidores de piridopirimidinona cdk2/4/6 |
| CN117982673A (zh) * | 2017-02-28 | 2024-05-07 | 第一三共株式会社 | 抗her3抗体-药物偶联物的应用 |
| TW202532104A (zh) | 2017-05-15 | 2025-08-16 | 日商第一三共股份有限公司 | 抗體-藥物結合物及其用途 |
| IL324591A (en) | 2017-08-31 | 2026-01-01 | Daiichi Sankyo Co Ltd | Improved antibody-drug conjugate production methods |
-
2019
- 2019-12-20 US US17/416,487 patent/US20220040324A1/en active Pending
- 2019-12-20 SG SG11202106635WA patent/SG11202106635WA/en unknown
- 2019-12-20 EP EP19899188.7A patent/EP3903828A4/en active Pending
- 2019-12-20 TW TW108147081A patent/TW202038957A/zh unknown
- 2019-12-20 KR KR1020217023043A patent/KR20210107069A/ko not_active Ceased
- 2019-12-20 CA CA3124330A patent/CA3124330A1/en active Pending
- 2019-12-20 AU AU2019407426A patent/AU2019407426A1/en active Pending
- 2019-12-20 WO PCT/JP2019/050017 patent/WO2020130125A1/ja not_active Ceased
- 2019-12-20 JP JP2020561537A patent/JPWO2020130125A1/ja not_active Withdrawn
- 2019-12-20 BR BR112021011894-2A patent/BR112021011894A2/pt unknown
- 2019-12-20 CN CN201980085178.1A patent/CN113195000A/zh active Pending
-
2024
- 2024-08-09 JP JP2024134653A patent/JP2024161445A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP3903828A1 (en) | 2021-11-03 |
| WO2020130125A1 (ja) | 2020-06-25 |
| BR112021011894A2 (pt) | 2021-09-08 |
| JPWO2020130125A1 (ja) | 2021-11-04 |
| SG11202106635WA (en) | 2021-07-29 |
| JP2024161445A (ja) | 2024-11-19 |
| CN113195000A (zh) | 2021-07-30 |
| CA3124330A1 (en) | 2020-06-25 |
| KR20210107069A (ko) | 2021-08-31 |
| EP3903828A4 (en) | 2022-10-05 |
| AU2019407426A1 (en) | 2021-07-22 |
| US20220040324A1 (en) | 2022-02-10 |
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