TW201919618A - 用於治療肉瘤的化合物 - Google Patents

用於治療肉瘤的化合物 Download PDF

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Publication number
TW201919618A
TW201919618A TW107120396A TW107120396A TW201919618A TW 201919618 A TW201919618 A TW 201919618A TW 107120396 A TW107120396 A TW 107120396A TW 107120396 A TW107120396 A TW 107120396A TW 201919618 A TW201919618 A TW 201919618A
Authority
TW
Taiwan
Prior art keywords
pharmaceutically acceptable
sarcoma
acceptable salt
patient
tinostamostatin
Prior art date
Application number
TW107120396A
Other languages
English (en)
Chinese (zh)
Inventor
湯瑪士 約爾格 梅林
Original Assignee
盧森堡商歐陸斯迪公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 盧森堡商歐陸斯迪公司 filed Critical 盧森堡商歐陸斯迪公司
Publication of TW201919618A publication Critical patent/TW201919618A/zh

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Radiology & Medical Imaging (AREA)
  • Pathology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
TW107120396A 2017-06-13 2018-06-13 用於治療肉瘤的化合物 TW201919618A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1709403.8A GB201709403D0 (en) 2017-06-13 2017-06-13 Compounds for treating sarcoma
??1709403.8 2017-06-13

Publications (1)

Publication Number Publication Date
TW201919618A true TW201919618A (zh) 2019-06-01

Family

ID=59358374

Family Applications (1)

Application Number Title Priority Date Filing Date
TW107120396A TW201919618A (zh) 2017-06-13 2018-06-13 用於治療肉瘤的化合物

Country Status (14)

Country Link
US (3) US11576899B2 (enExample)
EP (1) EP3638232B1 (enExample)
JP (1) JP2020523355A (enExample)
KR (1) KR20200014791A (enExample)
AR (1) AR112144A1 (enExample)
AU (1) AU2018285822B2 (enExample)
BR (1) BR112019026463A2 (enExample)
CA (1) CA3067065A1 (enExample)
ES (1) ES2970224T3 (enExample)
GB (1) GB201709403D0 (enExample)
IL (1) IL271020A (enExample)
MX (1) MX2019015212A (enExample)
TW (1) TW201919618A (enExample)
WO (1) WO2018229133A1 (enExample)

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GB201709403D0 (en) 2017-06-13 2017-07-26 Euro Celtique Sa Compounds for treating sarcoma
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EP3897626B1 (en) 2018-12-18 2025-09-10 Mundipharma International Corporation Limited Tinostamustine for treating multiple myeloma

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Also Published As

Publication number Publication date
EP3638232A1 (en) 2020-04-22
JP2020523355A (ja) 2020-08-06
US12257237B2 (en) 2025-03-25
WO2018229133A1 (en) 2018-12-20
EP3638232B1 (en) 2023-12-13
KR20200014791A (ko) 2020-02-11
ES2970224T3 (es) 2024-05-27
US11576899B2 (en) 2023-02-14
AR112144A1 (es) 2019-09-25
AU2018285822A1 (en) 2019-12-19
BR112019026463A2 (pt) 2020-07-14
US20200113870A1 (en) 2020-04-16
GB201709403D0 (en) 2017-07-26
AU2018285822B2 (en) 2024-01-04
CA3067065A1 (en) 2018-12-20
MX2019015212A (es) 2020-08-17
US20250375424A1 (en) 2025-12-11
US20230277507A1 (en) 2023-09-07
IL271020A (en) 2020-01-30
EP3638232C0 (en) 2023-12-13

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