JP2020523355A - 肉腫を処置することへの使用のためのチノスタムスチン - Google Patents

肉腫を処置することへの使用のためのチノスタムスチン Download PDF

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Publication number
JP2020523355A
JP2020523355A JP2019568646A JP2019568646A JP2020523355A JP 2020523355 A JP2020523355 A JP 2020523355A JP 2019568646 A JP2019568646 A JP 2019568646A JP 2019568646 A JP2019568646 A JP 2019568646A JP 2020523355 A JP2020523355 A JP 2020523355A
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JP
Japan
Prior art keywords
sarcoma
acceptable salt
pharmaceutically acceptable
tinostamustine
treatment
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Pending
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JP2019568646A
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English (en)
Japanese (ja)
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JP2020523355A5 (enExample
Inventor
トーマス・ヨーク・メーリング
Original Assignee
ユーロ−セルティーク エス．エイ．
ユーロ−セルティーク エス．エイ．
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Application filed by ユーロ−セルティーク エス．エイ．, ユーロ−セルティーク エス．エイ． filed Critical ユーロ−セルティーク エス．エイ．
Publication of JP2020523355A publication Critical patent/JP2020523355A/ja
Publication of JP2020523355A5 publication Critical patent/JP2020523355A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Radiology & Medical Imaging (AREA)
  • Pathology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2019568646A 2017-06-13 2018-06-13 肉腫を処置することへの使用のためのチノスタムスチン Pending JP2020523355A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1709403.8A GB201709403D0 (en) 2017-06-13 2017-06-13 Compounds for treating sarcoma
GB1709403.8 2017-06-13
PCT/EP2018/065668 WO2018229133A1 (en) 2017-06-13 2018-06-13 Tinostamustine for use in treating sarcoma

Publications (2)

Publication Number Publication Date
JP2020523355A true JP2020523355A (ja) 2020-08-06
JP2020523355A5 JP2020523355A5 (enExample) 2021-07-26

Family

ID=59358374

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019568646A Pending JP2020523355A (ja) 2017-06-13 2018-06-13 肉腫を処置することへの使用のためのチノスタムスチン

Country Status (14)

Country Link
US (3) US11576899B2 (enExample)
EP (1) EP3638232B1 (enExample)
JP (1) JP2020523355A (enExample)
KR (1) KR20200014791A (enExample)
AR (1) AR112144A1 (enExample)
AU (1) AU2018285822B2 (enExample)
BR (1) BR112019026463A2 (enExample)
CA (1) CA3067065A1 (enExample)
ES (1) ES2970224T3 (enExample)
GB (1) GB201709403D0 (enExample)
IL (1) IL271020A (enExample)
MX (1) MX2019015212A (enExample)
TW (1) TW201919618A (enExample)
WO (1) WO2018229133A1 (enExample)

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* Cited by examiner, † Cited by third party
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GB201409471D0 (en) 2014-05-28 2014-07-09 Euro Celtique Sa Pharmaceutical composition
GB201409485D0 (en) 2014-05-28 2014-07-09 Euro Celtique Sa Pharmaceutical composition
WO2018068832A1 (en) 2016-10-11 2018-04-19 Euro-Celtique S.A. Hodgkin lymphoma therapy
GB201709402D0 (en) 2017-06-13 2017-07-26 Euro Celtique Sa Compounds for treating t-pll
GB201709406D0 (en) 2017-06-13 2017-07-26 Euro-Cletique S A Compounds for treating TNBC
GB201709403D0 (en) 2017-06-13 2017-07-26 Euro Celtique Sa Compounds for treating sarcoma
GB201709405D0 (en) * 2017-06-13 2017-07-26 Euro Celtique Sa Compounds for treating ovarian cancer
EP3897626B1 (en) 2018-12-18 2025-09-10 Mundipharma International Corporation Limited Tinostamustine for treating multiple myeloma

Citations (1)

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Publication number Priority date Publication date Assignee Title
JP2014526512A (ja) * 2011-09-18 2014-10-06 ユーロ−セルティーク エス．エイ． 医薬組成物

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Also Published As

Publication number Publication date
EP3638232A1 (en) 2020-04-22
US12257237B2 (en) 2025-03-25
WO2018229133A1 (en) 2018-12-20
EP3638232B1 (en) 2023-12-13
KR20200014791A (ko) 2020-02-11
ES2970224T3 (es) 2024-05-27
US11576899B2 (en) 2023-02-14
AR112144A1 (es) 2019-09-25
AU2018285822A1 (en) 2019-12-19
BR112019026463A2 (pt) 2020-07-14
US20200113870A1 (en) 2020-04-16
GB201709403D0 (en) 2017-07-26
AU2018285822B2 (en) 2024-01-04
CA3067065A1 (en) 2018-12-20
MX2019015212A (es) 2020-08-17
US20250375424A1 (en) 2025-12-11
US20230277507A1 (en) 2023-09-07
TW201919618A (zh) 2019-06-01
IL271020A (en) 2020-01-30
EP3638232C0 (en) 2023-12-13

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