AU2018285822B2 - Tinostamustine for use in treating sarcoma - Google Patents

Tinostamustine for use in treating sarcoma Download PDF

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Publication number
AU2018285822B2
AU2018285822B2 AU2018285822A AU2018285822A AU2018285822B2 AU 2018285822 B2 AU2018285822 B2 AU 2018285822B2 AU 2018285822 A AU2018285822 A AU 2018285822A AU 2018285822 A AU2018285822 A AU 2018285822A AU 2018285822 B2 AU2018285822 B2 AU 2018285822B2
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AU
Australia
Prior art keywords
sarcoma
patient
tinostamustine
pharmaceutically acceptable
acceptable salt
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AU2018285822A
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English (en)
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AU2018285822A1 (en
Inventor
Thomas Jorg MEHRLING
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Euro Celtique SA
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Euro Celtique SA
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2018285822A 2017-06-13 2018-06-13 Tinostamustine for use in treating sarcoma Active AU2018285822B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1709403.8A GB201709403D0 (en) 2017-06-13 2017-06-13 Compounds for treating sarcoma
GB1709403.8 2017-06-13
PCT/EP2018/065668 WO2018229133A1 (en) 2017-06-13 2018-06-13 Tinostamustine for use in treating sarcoma

Publications (2)

Publication Number Publication Date
AU2018285822A1 AU2018285822A1 (en) 2019-12-19
AU2018285822B2 true AU2018285822B2 (en) 2024-01-04

Family

ID=59358374

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2018285822A Active AU2018285822B2 (en) 2017-06-13 2018-06-13 Tinostamustine for use in treating sarcoma

Country Status (14)

Country Link
US (3) US11576899B2 (enExample)
EP (1) EP3638232B1 (enExample)
JP (1) JP2020523355A (enExample)
KR (1) KR20200014791A (enExample)
AR (1) AR112144A1 (enExample)
AU (1) AU2018285822B2 (enExample)
BR (1) BR112019026463A2 (enExample)
CA (1) CA3067065A1 (enExample)
ES (1) ES2970224T3 (enExample)
GB (1) GB201709403D0 (enExample)
IL (1) IL271020A (enExample)
MX (1) MX2019015212A (enExample)
TW (1) TW201919618A (enExample)
WO (1) WO2018229133A1 (enExample)

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* Cited by examiner, † Cited by third party
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GB201409471D0 (en) 2014-05-28 2014-07-09 Euro Celtique Sa Pharmaceutical composition
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GB201709405D0 (en) * 2017-06-13 2017-07-26 Euro Celtique Sa Compounds for treating ovarian cancer
GB201709403D0 (en) 2017-06-13 2017-07-26 Euro Celtique Sa Compounds for treating sarcoma
GB201709402D0 (en) 2017-06-13 2017-07-26 Euro Celtique Sa Compounds for treating t-pll
GB201709406D0 (en) 2017-06-13 2017-07-26 Euro-Cletique S A Compounds for treating TNBC
WO2020128913A1 (en) 2018-12-18 2020-06-25 Mundipharma International Corporation Limited Compounds for treating multiple myeloma

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Also Published As

Publication number Publication date
US11576899B2 (en) 2023-02-14
WO2018229133A1 (en) 2018-12-20
AR112144A1 (es) 2019-09-25
MX2019015212A (es) 2020-08-17
JP2020523355A (ja) 2020-08-06
TW201919618A (zh) 2019-06-01
CA3067065A1 (en) 2018-12-20
AU2018285822A1 (en) 2019-12-19
US20200113870A1 (en) 2020-04-16
BR112019026463A2 (pt) 2020-07-14
US20230277507A1 (en) 2023-09-07
IL271020A (en) 2020-01-30
GB201709403D0 (en) 2017-07-26
ES2970224T3 (es) 2024-05-27
US20250375424A1 (en) 2025-12-11
KR20200014791A (ko) 2020-02-11
EP3638232B1 (en) 2023-12-13
EP3638232A1 (en) 2020-04-22
US12257237B2 (en) 2025-03-25
EP3638232C0 (en) 2023-12-13

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