TW201522378A - 用於治療人類癌症的特異性抗ｃｄ３８抗體 - Google Patents
用於治療人類癌症的特異性抗ｃｄ３８抗體 Download PDFInfo
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- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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Landscapes
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| UA112170C2 (uk) | 2010-12-10 | 2016-08-10 | Санофі | Протипухлинна комбінація, що містить антитіло, яке специфічно розпізнає cd38, і бортезоміб |
| JOP20210044A1 (ar) | 2010-12-30 | 2017-06-16 | Takeda Pharmaceuticals Co | الأجسام المضادة لـ cd38 |
| US10342869B2 (en) * | 2012-12-07 | 2019-07-09 | The Regents Of The University Of California | Compositions comprising anti-CD38 antibodies and lenalidomide |
| CN112043826A (zh) * | 2013-03-13 | 2020-12-08 | 赛诺菲 | 包含抗cd38抗体和卡非佐米的组合物 |
| US9732154B2 (en) | 2014-02-28 | 2017-08-15 | Janssen Biotech, Inc. | Anti-CD38 antibodies for treatment of acute lymphoblastic leukemia |
| US9603927B2 (en) | 2014-02-28 | 2017-03-28 | Janssen Biotech, Inc. | Combination therapies with anti-CD38 antibodies |
| MA40608A (fr) | 2014-09-09 | 2016-03-17 | Janssen Biotech Inc | Polythérapies avec des anticorps anti-cd38 |
| JP6802791B2 (ja) | 2014-12-04 | 2020-12-23 | ヤンセン バイオテツク，インコーポレーテツド | 急性骨髄性白血病の治療のための抗ｃｄ３８抗体 |
| HUE054271T2 (hu) * | 2015-05-13 | 2021-08-30 | Morphosys Ag | Mielóma Multiplex (MM) kezelése |
| EP4553157A3 (en) | 2015-05-20 | 2025-07-23 | Janssen Biotech, Inc. | Anti-cd38 antibodies for treatment of light chain amyloidosis and other cd38-positive hematological malignancies |
| EP3303373B1 (en) | 2015-05-30 | 2020-04-08 | Molecular Templates, Inc. | De-immunized, shiga toxin a subunit scaffolds and cell-targeting molecules comprising the same |
| WO2016201337A1 (en) * | 2015-06-12 | 2016-12-15 | Immungene, Inc. | Engineered antibody-interferon fusion molecules for the treatment of glucose-regulated protein 94 (grp94) expressing cancers |
| UA125115C2 (uk) | 2015-06-22 | 2022-01-12 | Янссен Байотек, Інк. | Спосіб лікування суб'єкта, який має множинну мієлому (мм) |
| US20170044265A1 (en) | 2015-06-24 | 2017-02-16 | Janssen Biotech, Inc. | Immune Modulation and Treatment of Solid Tumors with Antibodies that Specifically Bind CD38 |
| US10781261B2 (en) | 2015-11-03 | 2020-09-22 | Janssen Biotech, Inc. | Subcutaneous formulations of anti-CD38 antibodies and their uses |
| JP7027321B2 (ja) | 2015-11-03 | 2022-03-01 | ヤンセン バイオテツク，インコーポレーテツド | 抗ｃｄ３８抗体の皮下製剤及びその使用 |
| JP7362250B2 (ja) | 2016-03-04 | 2023-10-17 | モルフォシス・アーゲー | 多発性骨髄腫におけるｍタンパク質反応の臨床評価 |
| WO2017223111A1 (en) | 2016-06-21 | 2017-12-28 | Teneobio, Inc. | Cd3 binding antibodies |
| JP7316930B2 (ja) | 2016-07-15 | 2023-07-28 | 武田薬品工業株式会社 | 形質芽細胞及び形質細胞枯渇療法に対する応答を評価するための方法及び材料 |
| HRP20240767T1 (hr) | 2016-09-14 | 2024-09-13 | Teneoone, Inc. | Cd3 vezujuća antitijela |
| NZ754713A (en) | 2016-12-21 | 2025-11-28 | Teneobio Inc | Anti-bcma heavy chain-only antibodies |
| CN117567624A (zh) | 2017-06-20 | 2024-02-20 | 特纳奥尼股份有限公司 | 仅有重链的抗bcma抗体 |
| CN117866097A (zh) | 2017-06-20 | 2024-04-12 | 特尼奥生物股份有限公司 | 仅有重链的抗bcma抗体 |
| JPWO2019031444A1 (ja) * | 2017-08-07 | 2020-08-27 | 国立大学法人九州大学 | 細胞集団における特異的結合物質の占有率を測定する方法 |
| WO2019035938A1 (en) | 2017-08-16 | 2019-02-21 | Elstar Therapeutics, Inc. | MULTISPECIFIC MOLECULES BINDING TO BCMA AND USES THEREOF |
| CN111133007A (zh) * | 2017-09-13 | 2020-05-08 | 特尼奥生物股份有限公司 | 与胞外酶结合的重链抗体 |
| JP2021502961A (ja) | 2017-10-31 | 2021-02-04 | ヤンセン バイオテツク，インコーポレーテツド | 高リスク多発性骨髄腫の治療方法 |
| CN111542545A (zh) | 2017-11-03 | 2020-08-14 | 索伦托治疗有限公司 | Cd38定向嵌合抗原受体构建体 |
| CN112739715A (zh) | 2018-01-12 | 2021-04-30 | 武田药品工业株式会社 | 抗cd38抗体的皮下给药 |
| MX2020010144A (es) * | 2018-03-28 | 2020-12-07 | Takeda Pharmaceuticals Co | Dosificación subcutánea de anticuerpos anti grupo de diferenciación 38 (cd38). |
| BR112021000065A2 (pt) * | 2018-07-10 | 2021-04-06 | Sanofi | Terapias de combinação contra câncer direcionando cd38 e tgf-beta |
| MX2021007047A (es) | 2018-12-14 | 2021-10-26 | Morphosys Ag | Formulaciones de anticuerpos. |
| CN113853204A (zh) * | 2019-03-21 | 2021-12-28 | 盖米达细胞有限公司 | 适用于移植组合疗法的扩增nk细胞组分的扩增及其用途 |
| MX2021012205A (es) | 2019-04-05 | 2022-02-21 | Teneobio Inc | Anticuerpos de cadena pesada que se unen al psma. |
| US11655302B2 (en) | 2019-06-10 | 2023-05-23 | Sanofi | Anti-CD38 antibodies and formulations |
| TWI872082B (zh) | 2019-06-14 | 2025-02-11 | 美商泰尼歐生物公司 | 與ｃ ｄ ２ ２ 及ｃ ｄ ３ 結合之多特異性重鏈抗體 |
| CN112876563B (zh) * | 2019-11-29 | 2022-08-16 | 康诺亚生物医药科技（成都）有限公司 | 药物组合物及其制备方法和应用 |
| KR20220159947A (ko) | 2019-12-05 | 2022-12-05 | 사노피-아벤티스 유.에스. 엘엘씨 | 피하 투여를 위한 항-cd38 항체의 제형 |
| EP4069740A1 (en) * | 2019-12-06 | 2022-10-12 | Sanofi-Aventis U.S. LLC | Use of isatuximab for the treatment of relapsed and/or refractory multiple myeloma |
| WO2021259227A1 (zh) * | 2020-06-23 | 2021-12-30 | 江苏康缘药业股份有限公司 | 抗cd38抗体及其用途 |
| JP2024508207A (ja) | 2020-12-02 | 2024-02-26 | ブイアイビー ブイゼットダブリュ | がんに対する組み合わせ治療におけるｌｔｂｒアゴニスト |
| US20250382378A1 (en) * | 2022-10-31 | 2025-12-18 | Genmab A/S | Cd38 antibodies and uses thereof |
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| EP2191841A1 (en) * | 2008-11-28 | 2010-06-02 | Sanofi-Aventis | Antitumor combinations containing antibodies recognizing specifically CD38 and vincristine |
| EP2191842A1 (en) | 2008-11-28 | 2010-06-02 | Sanofi-Aventis | Antitumor combinations containing antibodies recognizing specifically CD38 and cytarabine |
| EP2191840A1 (en) * | 2008-11-28 | 2010-06-02 | Sanofi-Aventis | Antitumor combinations containing antibodies recognizing specifically CD38 and melphalan |
| UA112170C2 (uk) * | 2010-12-10 | 2016-08-10 | Санофі | Протипухлинна комбінація, що містить антитіло, яке специфічно розпізнає cd38, і бортезоміб |
| JOP20210044A1 (ar) * | 2010-12-30 | 2017-06-16 | Takeda Pharmaceuticals Co | الأجسام المضادة لـ cd38 |
| EA034989B1 (ru) * | 2011-10-28 | 2020-04-15 | Тева Фармасьютикал Австралия Пти Лтд | Полипептидная конструкция для применения при лечении рака, включающая аттенуированный альфа-интерферон |
| US10342869B2 (en) * | 2012-12-07 | 2019-07-09 | The Regents Of The University Of California | Compositions comprising anti-CD38 antibodies and lenalidomide |
| CN112043826A (zh) * | 2013-03-13 | 2020-12-08 | 赛诺菲 | 包含抗cd38抗体和卡非佐米的组合物 |
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2014
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- 2014-10-31 PL PL14799089T patent/PL3063173T3/pl unknown
- 2014-10-31 TW TW103137932A patent/TW201522378A/zh unknown
- 2014-10-31 WO PCT/US2014/063380 patent/WO2015066450A1/en not_active Ceased
- 2014-10-31 MA MA39070A patent/MA39070A1/fr unknown
- 2014-10-31 JP JP2016527374A patent/JP2016536314A/ja active Pending
- 2014-10-31 SG SG11201603088RA patent/SG11201603088RA/en unknown
- 2014-10-31 CA CA2927099A patent/CA2927099A1/en not_active Abandoned
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- 2014-10-31 MX MX2016005666A patent/MX373301B/es active IP Right Grant
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- 2014-10-31 MA MA44560A patent/MA44560B2/fr unknown
- 2014-10-31 NZ NZ719784A patent/NZ719784A/en unknown
- 2014-10-31 PT PT147990899T patent/PT3063173T/pt unknown
- 2014-10-31 KR KR1020167013974A patent/KR20160077155A/ko not_active Ceased
- 2014-10-31 AU AU2014342103A patent/AU2014342103B2/en active Active
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- 2014-10-31 CN CN201480071448.0A patent/CN106103481A/zh active Pending
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2016
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2017
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2023
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| Publication number | Publication date |
|---|---|
| US20180022814A1 (en) | 2018-01-25 |
| SG10201803288RA (en) | 2018-05-30 |
| EA035098B1 (ru) | 2020-04-27 |
| AU2014342103A1 (en) | 2016-05-26 |
| CA2927099A1 (en) | 2015-05-07 |
| EP3805266A1 (en) | 2021-04-14 |
| MX373301B (es) | 2020-04-24 |
| JP2023109927A (ja) | 2023-08-08 |
| CR20160186A (es) | 2016-06-13 |
| EP3063173A1 (en) | 2016-09-07 |
| PL3063173T3 (pl) | 2021-01-11 |
| IL245196A0 (en) | 2016-06-30 |
| BR112016009403A2 (pt) | 2017-09-19 |
| MA44560A1 (fr) | 2019-09-30 |
| EP3063173B1 (en) | 2020-07-29 |
| EA201690905A1 (ru) | 2016-08-31 |
| JP2025139586A (ja) | 2025-09-26 |
| WO2015066450A1 (en) | 2015-05-07 |
| MA44560B1 (fr) | 2020-06-30 |
| US20150118251A1 (en) | 2015-04-30 |
| PT3063173T (pt) | 2020-10-20 |
| MX2016005666A (es) | 2016-07-14 |
| CN106103481A (zh) | 2016-11-09 |
| KR20160077155A (ko) | 2016-07-01 |
| MA44560B2 (fr) | 2021-01-29 |
| NZ719784A (en) | 2022-02-25 |
| AU2014342103B2 (en) | 2020-06-04 |
| SG11201603088RA (en) | 2016-05-30 |
| IL245196B (en) | 2021-04-29 |
| JP2016536314A (ja) | 2016-11-24 |
| MA39070A1 (fr) | 2017-11-30 |
| TN2016000142A1 (en) | 2017-10-06 |
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