TW200932229A - Quinoline derivatives 057 - Google Patents

Quinoline derivatives 057 Download PDF

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Publication number
TW200932229A
TW200932229A TW097146304A TW97146304A TW200932229A TW 200932229 A TW200932229 A TW 200932229A TW 097146304 A TW097146304 A TW 097146304A TW 97146304 A TW97146304 A TW 97146304A TW 200932229 A TW200932229 A TW 200932229A
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TW
Taiwan
Prior art keywords
compound
pharmaceutically acceptable
acceptable salt
formula
disease
Prior art date
Application number
TW097146304A
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English (en)
Chinese (zh)
Inventor
Simon David Guile
Toby Thompson
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of TW200932229A publication Critical patent/TW200932229A/zh

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Endocrinology (AREA)
  • Virology (AREA)
  • Reproductive Health (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
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TW097146304A 2007-11-30 2008-11-28 Quinoline derivatives 057 TW200932229A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US99126507P 2007-11-30 2007-11-30

Publications (1)

Publication Number Publication Date
TW200932229A true TW200932229A (en) 2009-08-01

Family

ID=40676391

Family Applications (1)

Application Number Title Priority Date Filing Date
TW097146304A TW200932229A (en) 2007-11-30 2008-11-28 Quinoline derivatives 057

Country Status (9)

Country Link
US (1) US8106073B2 (enExample)
EP (1) EP2225222B1 (enExample)
JP (1) JP2011505356A (enExample)
AR (1) AR069508A1 (enExample)
AT (1) ATE524458T1 (enExample)
ES (1) ES2370960T3 (enExample)
PE (1) PE20091036A1 (enExample)
TW (1) TW200932229A (enExample)
WO (1) WO2009070116A1 (enExample)

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US8106073B2 (en) 2007-11-30 2012-01-31 Astrazeneca Ab Quinoline derivatives 057
PH12012501222A1 (en) * 2009-12-17 2012-11-05 Merck Sharp & Dohme Quinoline amide m1 receptor positive allosteric modulators
WO2012110190A1 (en) 2011-02-17 2012-08-23 Affectis Pharmaceuticals Ag Novel p2x7r antagonists and their use
WO2012163456A1 (en) 2011-05-27 2012-12-06 Affectis Pharmaceuticals Ag Novel p2x7r antagonists and their use
WO2012163792A1 (en) 2011-05-27 2012-12-06 Affectis Pharmaceuticals Ag Novel p2x7r antagonists and their use
KR101995088B1 (ko) 2011-07-22 2019-07-02 이도르시아 파마슈티컬스 리미티드 Ｐ2ｘ7 수용체 길항제로서의 헤테로시클릭 아미드 유도체
NZ628910A (en) 2012-01-20 2016-02-26 Actelion Pharmaceuticals Ltd Heterocyclic amide derivatives as p2x7 receptor antagonists
PL2931717T3 (pl) 2012-12-12 2017-05-31 Actelion Pharmaceuticals Ltd. Pochodne indolokarboksyamidu jako antagoniści receptora p2x7
US9556117B2 (en) 2012-12-18 2017-01-31 Actelion Pharmaceuticals Ltd. Indole carboxamide derivatives as P2X7 receptor antagonists
KR102222220B1 (ko) 2013-01-22 2021-03-03 이도르시아 파마슈티컬스 리미티드 Ｐ2ｘ7 수용체 길항제로서의 헤테로시클릭 아미드 유도체
WO2014115078A1 (en) 2013-01-22 2014-07-31 Actelion Pharmaceuticals Ltd Heterocyclic amide derivatives as p2x7 receptor antagonists
AU2015269598B2 (en) * 2014-06-05 2019-11-14 Merck Patent Gmbh Novel quinoline derivatives and their use in neurodegenerative diseases
EP3962493A2 (en) 2019-05-03 2022-03-09 Flagship Pioneering Innovations V, Inc. Methods of modulating immune activity/level of irf or sting or of treating cancer, comprising the administration of a sting modulator and/or purinergic receptor modulator or postcellular signaling factor

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EP2225222A1 (en) 2010-09-08
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US8106073B2 (en) 2012-01-31
WO2009070116A1 (en) 2009-06-04
ES2370960T3 (es) 2011-12-26
JP2011505356A (ja) 2011-02-24
ATE524458T1 (de) 2011-09-15
HK1148002A1 (en) 2011-08-26
US20090143428A1 (en) 2009-06-04
EP2225222B1 (en) 2011-09-14
AR069508A1 (es) 2010-01-27

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