TW200530399A - Recombinant nucleic acid molecules, expression cassettes, and bacteria, and methods of use thereof - Google Patents

Recombinant nucleic acid molecules, expression cassettes, and bacteria, and methods of use thereof Download PDF

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Publication number
TW200530399A
TW200530399A TW093140281A TW93140281A TW200530399A TW 200530399 A TW200530399 A TW 200530399A TW 093140281 A TW093140281 A TW 093140281A TW 93140281 A TW93140281 A TW 93140281A TW 200530399 A TW200530399 A TW 200530399A
Authority
TW
Taiwan
Prior art keywords
antigen
polynucleotide
recombinant
signal peptide
nucleic acid
Prior art date
Application number
TW093140281A
Other languages
English (en)
Chinese (zh)
Inventor
Thomas W Dubensky Jr
Daniel A Portnoy
William Stanford Luckett Jr
David N Cook
Original Assignee
Cerus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/773,792 external-priority patent/US7691393B2/en
Priority claimed from US10/773,618 external-priority patent/US7833775B2/en
Priority claimed from US10/883,599 external-priority patent/US7695725B2/en
Application filed by Cerus Corp filed Critical Cerus Corp
Publication of TW200530399A publication Critical patent/TW200530399A/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
TW093140281A 2003-12-24 2004-12-23 Recombinant nucleic acid molecules, expression cassettes, and bacteria, and methods of use thereof TW200530399A (en)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US53259803P 2003-12-24 2003-12-24
US54151504P 2004-02-02 2004-02-02
US10/773,792 US7691393B2 (en) 2003-02-06 2004-02-06 Listeria attenuated for entry into non-phagocytic cells, vaccines comprising the Listeria, and methods of use thereof
US10/773,618 US7833775B2 (en) 2003-02-06 2004-02-06 Modified free-living microbes, vaccine compositions and methods of use thereof
US55674404P 2004-03-26 2004-03-26
US10/883,599 US7695725B2 (en) 2003-02-06 2004-06-30 Modified free-living microbes, vaccine compositions and methods of use thereof
PCT/US2004/023881 WO2005009463A2 (en) 2003-07-24 2004-07-23 Antigen-presenting cell vaccines and methods of use thereof
US59937704P 2004-08-05 2004-08-05
US61528704P 2004-10-01 2004-10-01
US61675004P 2004-10-06 2004-10-06

Publications (1)

Publication Number Publication Date
TW200530399A true TW200530399A (en) 2005-09-16

Family

ID=44588533

Family Applications (1)

Application Number Title Priority Date Filing Date
TW093140281A TW200530399A (en) 2003-12-24 2004-12-23 Recombinant nucleic acid molecules, expression cassettes, and bacteria, and methods of use thereof

Country Status (3)

Country Link
JP (2) JP5532280B2 (enExample)
CN (1) CN1921884B (enExample)
TW (1) TW200530399A (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2535421T3 (es) * 2011-03-22 2015-05-11 Mucosis B.V. Composiciones inmunogénicas en forma particulada y métodos para producir las mismas
CN102766601B (zh) * 2011-11-17 2015-12-16 中山大学肿瘤防治中心 含有可诱导型癌基因的细胞系及其建立方法、应用
EP3763383A1 (en) * 2013-12-16 2021-01-13 Massachusetts Institute Of Technology Micromolded or 3-d printed pulsatile release vaccine formulations
LT3037530T (lt) * 2014-12-22 2017-04-10 Sandoz Ag Sekos variantai
CN105039381B (zh) * 2015-07-21 2018-02-13 齐鲁工业大学 一种麦芽糖诱导型海藻糖合酶合成工程菌及其制备方法与应用
CN107229842A (zh) * 2017-06-02 2017-10-03 肖传乐 一种基于局部图的三代测序序列校正方法
CN115894639B (zh) * 2022-11-03 2024-05-14 大连医诺生物股份有限公司 一种辅助侵染蛋白残基突变体蛋白、其重组体及在外泌酶固定化工艺中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5830702A (en) * 1990-10-31 1998-11-03 The Trustees Of The University Of Pennsylvania Live, recombinant listeria monocytogenes and production of cytotoxic T-cell response
FR2686896B1 (fr) * 1992-01-31 1995-01-06 Pasteur Institut Mutant attenue de listeria monocytogenes; souche recombinante de listeria monocytogenes, utilisation comme vecteurs heterologues d'antigenes vaccinal et utilisation comme vaccin ou composition diagnostique.
DE19949594A1 (de) * 1999-10-14 2001-04-26 Deutsches Krebsforsch Rekombinante attenuierte Listerien zur Immuntherapie

Also Published As

Publication number Publication date
CN1921884A (zh) 2007-02-28
JP2007518405A (ja) 2007-07-12
HK1098673A1 (zh) 2007-07-27
JP5532280B2 (ja) 2014-06-25
CN1921884B (zh) 2012-02-08
JP2011155988A (ja) 2011-08-18

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