CN1921884B - 重组核酸分子,表达盒和细菌,及其使用方法 - Google Patents

重组核酸分子,表达盒和细菌,及其使用方法 Download PDF

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Publication number
CN1921884B
CN1921884B CN200480042020XA CN200480042020A CN1921884B CN 1921884 B CN1921884 B CN 1921884B CN 200480042020X A CN200480042020X A CN 200480042020XA CN 200480042020 A CN200480042020 A CN 200480042020A CN 1921884 B CN1921884 B CN 1921884B
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CN
China
Prior art keywords
signal peptide
antigen
polypeptide
polynucleotide
nucleic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN200480042020XA
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English (en)
Chinese (zh)
Other versions
CN1921884A (zh
Inventor
T·W·小杜本斯基
D·A·波特努瓦
W·S·小勒基特
D·N·库克
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Anza Treatment Co
Chinook Therapeutics Inc
Original Assignee
Cerus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/773,792 external-priority patent/US7691393B2/en
Priority claimed from US10/773,618 external-priority patent/US7833775B2/en
Priority claimed from US10/883,599 external-priority patent/US7695725B2/en
Application filed by Cerus Corp filed Critical Cerus Corp
Priority claimed from PCT/US2004/044080 external-priority patent/WO2005071088A2/en
Publication of CN1921884A publication Critical patent/CN1921884A/zh
Application granted granted Critical
Publication of CN1921884B publication Critical patent/CN1921884B/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CN200480042020XA 2003-12-24 2004-12-23 重组核酸分子,表达盒和细菌,及其使用方法 Expired - Fee Related CN1921884B (zh)

Applications Claiming Priority (21)

Application Number Priority Date Filing Date Title
US53259803P 2003-12-24 2003-12-24
US60/532,598 2003-12-24
US54151504P 2004-02-02 2004-02-02
US60/541,515 2004-02-02
US10/773,792 US7691393B2 (en) 2003-02-06 2004-02-06 Listeria attenuated for entry into non-phagocytic cells, vaccines comprising the Listeria, and methods of use thereof
US10/773,618 2004-02-06
US10/773,618 US7833775B2 (en) 2003-02-06 2004-02-06 Modified free-living microbes, vaccine compositions and methods of use thereof
US10/773,792 2004-02-06
US55674404P 2004-03-26 2004-03-26
US60/556,744 2004-03-26
US10/883,599 US7695725B2 (en) 2003-02-06 2004-06-30 Modified free-living microbes, vaccine compositions and methods of use thereof
US10/883,599 2004-06-30
USPCT/US2004/023881 2004-07-23
PCT/US2004/023881 WO2005009463A2 (en) 2003-07-24 2004-07-23 Antigen-presenting cell vaccines and methods of use thereof
US59937704P 2004-08-05 2004-08-05
US60/599,377 2004-08-05
US61528704P 2004-10-01 2004-10-01
US60/615,287 2004-10-01
US61675004P 2004-10-06 2004-10-06
US60/616,750 2004-10-06
PCT/US2004/044080 WO2005071088A2 (en) 2003-12-24 2004-12-23 Recombinant nucleic acid molecules encoding fusion proteins comprising antigens and bacterial secretory signal polypeptides, expression cassettes, and bacteria, and methods of use thereof

Publications (2)

Publication Number Publication Date
CN1921884A CN1921884A (zh) 2007-02-28
CN1921884B true CN1921884B (zh) 2012-02-08

Family

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Family Applications (1)

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CN200480042020XA Expired - Fee Related CN1921884B (zh) 2003-12-24 2004-12-23 重组核酸分子,表达盒和细菌,及其使用方法

Country Status (3)

Country Link
JP (2) JP5532280B2 (enExample)
CN (1) CN1921884B (enExample)
TW (1) TW200530399A (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2535421T3 (es) * 2011-03-22 2015-05-11 Mucosis B.V. Composiciones inmunogénicas en forma particulada y métodos para producir las mismas
CN102766601B (zh) * 2011-11-17 2015-12-16 中山大学肿瘤防治中心 含有可诱导型癌基因的细胞系及其建立方法、应用
EP3763383A1 (en) * 2013-12-16 2021-01-13 Massachusetts Institute Of Technology Micromolded or 3-d printed pulsatile release vaccine formulations
LT3037530T (lt) * 2014-12-22 2017-04-10 Sandoz Ag Sekos variantai
CN105039381B (zh) * 2015-07-21 2018-02-13 齐鲁工业大学 一种麦芽糖诱导型海藻糖合酶合成工程菌及其制备方法与应用
CN107229842A (zh) * 2017-06-02 2017-10-03 肖传乐 一种基于局部图的三代测序序列校正方法
CN115894639B (zh) * 2022-11-03 2024-05-14 大连医诺生物股份有限公司 一种辅助侵染蛋白残基突变体蛋白、其重组体及在外泌酶固定化工艺中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5830702A (en) * 1990-10-31 1998-11-03 The Trustees Of The University Of Pennsylvania Live, recombinant listeria monocytogenes and production of cytotoxic T-cell response
FR2686896B1 (fr) * 1992-01-31 1995-01-06 Pasteur Institut Mutant attenue de listeria monocytogenes; souche recombinante de listeria monocytogenes, utilisation comme vecteurs heterologues d'antigenes vaccinal et utilisation comme vaccin ou composition diagnostique.
DE19949594A1 (de) * 1999-10-14 2001-04-26 Deutsches Krebsforsch Rekombinante attenuierte Listerien zur Immuntherapie

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Carlos A. Guzman et al.Attenuated Listeria monocytogenes carrier strainscandeliveran HIV-1 gp120 T helper epitope to MHCclassII-restrictedhuman CD4+ T cells..Eur. J. Immunol28.1998,281808. *
Hao Shen et al.Recombinant Listeria monocytogenes as a livevaccinevehiclefor the induction of protective anti-viralcell-mediatedimmunity..Proc. Natl. Acad. Sci. USA92.1995,923988,图1. *

Also Published As

Publication number Publication date
CN1921884A (zh) 2007-02-28
JP2007518405A (ja) 2007-07-12
HK1098673A1 (zh) 2007-07-27
TW200530399A (en) 2005-09-16
JP5532280B2 (ja) 2014-06-25
JP2011155988A (ja) 2011-08-18

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Owner name: ARTURO BIOTECHNOLOGY CORPORATION

Free format text: FORMER OWNER: ANZA THERAPEUTICS, INC.

Effective date: 20120109

Owner name: ANZA THERAPEUTICS, INC.

Free format text: FORMER OWNER: CERUS CORP.

Effective date: 20120109

C41 Transfer of patent application or patent right or utility model
TR01 Transfer of patent right

Effective date of registration: 20120109

Address after: American California

Patentee after: Aduro Biotech, Inc.

Address before: Delaware

Patentee before: Anza treatment Co.

Effective date of registration: 20120109

Address after: Delaware

Patentee after: Anza treatment Co.

Address before: American California

Patentee before: Cerus Corp.

CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20120208

Termination date: 20181223

CF01 Termination of patent right due to non-payment of annual fee