TR201909389T4 - Terapötik nanopartikülleri hazırlamaya yönelik proses. - Google Patents

Terapötik nanopartikülleri hazırlamaya yönelik proses. Download PDF

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Publication number
TR201909389T4
TR201909389T4 TR2019/09389T TR201909389T TR201909389T4 TR 201909389 T4 TR201909389 T4 TR 201909389T4 TR 2019/09389 T TR2019/09389 T TR 2019/09389T TR 201909389 T TR201909389 T TR 201909389T TR 201909389 T4 TR201909389 T4 TR 201909389T4
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TR
Turkey
Prior art keywords
therapeutic nanoparticles
preparing therapeutic
nanoparticles
therapeutic
present disclosure
Prior art date
Application number
TR2019/09389T
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English (en)
Inventor
Figueiredo Maria
Peeke Erick
Dewitt David
Van Geen Hoven Christina
Troiano Greg
Wright James
Song Young-Ho
Wang Hong
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Pfizer
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Application filed by Pfizer filed Critical Pfizer
Publication of TR201909389T4 publication Critical patent/TR201909389T4/tr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Abstract

Mevcut açıklama genel olarak terapötik nanopartiküllerin hazırlanmasına yönelik bir proses ile ilgilidir, buradaki proses, bir terapötik ajanın bir organik asit ile birleştirilmesini içerir. Terapötik nanopartiküller, örneğin geliştirilmiş ilaç yüküne ve/veya ilaç salım özelliklerine sahip olabilir.
TR2019/09389T 2012-09-17 2013-09-16 Terapötik nanopartikülleri hazırlamaya yönelik proses. TR201909389T4 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261702037P 2012-09-17 2012-09-17

Publications (1)

Publication Number Publication Date
TR201909389T4 true TR201909389T4 (tr) 2019-07-22

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Family Applications (1)

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TR2019/09389T TR201909389T4 (tr) 2012-09-17 2013-09-16 Terapötik nanopartikülleri hazırlamaya yönelik proses.

Country Status (23)

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US (1) US9877923B2 (tr)
EP (1) EP2895156B1 (tr)
JP (1) JP6356678B2 (tr)
KR (1) KR20150056618A (tr)
CN (1) CN104812381B (tr)
AU (1) AU2013315118B2 (tr)
BR (1) BR112015005940A2 (tr)
CA (1) CA2885193C (tr)
DK (1) DK2895156T3 (tr)
EA (1) EA032943B1 (tr)
ES (1) ES2732377T3 (tr)
HK (1) HK1211470A1 (tr)
HU (1) HUE043998T2 (tr)
IL (1) IL237780A0 (tr)
MX (1) MX356097B (tr)
MY (1) MY179194A (tr)
NZ (1) NZ705812A (tr)
PL (1) PL2895156T3 (tr)
PT (1) PT2895156T (tr)
SG (1) SG11201502065UA (tr)
SI (1) SI2895156T1 (tr)
TR (1) TR201909389T4 (tr)
WO (1) WO2014043618A1 (tr)

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