TR201905395T4 - Anti-gremlin-1 antikoru. - Google Patents

Anti-gremlin-1 antikoru. Download PDF

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Publication number
TR201905395T4
TR201905395T4 TR2019/05395T TR201905395T TR201905395T4 TR 201905395 T4 TR201905395 T4 TR 201905395T4 TR 2019/05395 T TR2019/05395 T TR 2019/05395T TR 201905395 T TR201905395 T TR 201905395T TR 201905395 T4 TR201905395 T4 TR 201905395T4
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Turkey
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gremlin
antibody
present
cancer
treatment
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TR2019/05395T
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English (en)
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Kim Hyun-Kee
Chung Junho
Soo Kim Min
Min Yoon Soo
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Hyun Kee Kim
Snu R&Db Foundation
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Publication of TR201905395T4 publication Critical patent/TR201905395T4/tr

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Abstract

Mevcut buluş, Gremlin-1?i kemik morfogenetik proteininden (BMP) veya vasküler endotelyal büyüme faktörü reseptörü-2?den (VEGFR-2) bağımsız bir şekilde inhibe eden bir Gremlin-1 antikoru ile ilgilidir, böylece kanser tedavisinin etkisini sağlamaktadır. Mevcut buluşa ait antikor, Gremlin-1?e bağımlı olan hücre migrasyonunu, hücre invazyonunu ve hücre çoğalmasını inhibe eder ve bu nedenle kanser veya immün hastalık tedavisinde etkili bir şekilde kullanılabilir.
TR2019/05395T 2012-03-15 2013-03-15 Anti-gremlin-1 antikoru. TR201905395T4 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261611285P 2012-03-15 2012-03-15

Publications (1)

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TR201905395T4 true TR201905395T4 (tr) 2019-05-21

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TR2019/05395T TR201905395T4 (tr) 2012-03-15 2013-03-15 Anti-gremlin-1 antikoru.

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US (1) US9631011B2 (tr)
EP (1) EP2826790B1 (tr)
JP (1) JP6339063B2 (tr)
KR (1) KR102119223B1 (tr)
CN (1) CN104321342B (tr)
AU (1) AU2013232855B2 (tr)
ES (1) ES2720617T3 (tr)
TR (1) TR201905395T4 (tr)
WO (1) WO2013137686A1 (tr)

Families Citing this family (13)

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AU2014241442B2 (en) * 2013-03-14 2018-11-15 Regeneron Pharmaceuticals, Inc. Human antibodies to GREM 1
DE202014007202U1 (de) 2014-09-03 2014-11-24 Lg Electronics Inc. Wäschebehandlungsvorrichtung
CN106399316B (zh) * 2016-08-26 2019-03-01 西安交通大学第一附属医院 用于识别Gremlin-1的核酸适配子及其应用
GB201621635D0 (en) 2016-12-19 2017-02-01 Ucb Biopharma Sprl Crystal structure
JP7033601B2 (ja) * 2017-01-05 2022-03-10 コリア リサーチ インスティチュート オブ バイオサイエンス アンド バイオテクノロジー 抗コチニンキメラ抗原受容体を発現するナチュラルキラー細胞
GB201802486D0 (en) 2018-02-15 2018-04-04 Ucb Biopharma Sprl Methods
JP2021528400A (ja) * 2018-06-18 2021-10-21 ユーシービー バイオファルマ エスアールエル がんを予防及び治療するためのｇｒｅｍｌｉｎ−１アンタゴニスト
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Also Published As

Publication number Publication date
KR102119223B1 (ko) 2020-06-05
KR20130105541A (ko) 2013-09-25
CN104321342A (zh) 2015-01-28
ES2720617T3 (es) 2019-07-23
JP6339063B2 (ja) 2018-06-06
JP2015512894A (ja) 2015-04-30
WO2013137686A1 (ko) 2013-09-19
AU2013232855A1 (en) 2014-10-02
AU2013232855B2 (en) 2016-10-27
CN104321342B (zh) 2017-12-22
EP2826790A4 (en) 2015-11-25
EP2826790A1 (en) 2015-01-21
US9631011B2 (en) 2017-04-25
EP2826790B1 (en) 2019-02-13
US20150158938A1 (en) 2015-06-11

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