TR201807202T4 - CD70 antikorları. - Google Patents
CD70 antikorları. Download PDFInfo
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- TR201807202T4 TR201807202T4 TR2018/07202T TR201807202T TR201807202T4 TR 201807202 T4 TR201807202 T4 TR 201807202T4 TR 2018/07202 T TR2018/07202 T TR 2018/07202T TR 201807202 T TR201807202 T TR 201807202T TR 201807202 T4 TR201807202 T4 TR 201807202T4
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Classifications
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- C07K2317/734—Complement-dependent cytotoxicity [CDC]
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- C07K—PEPTIDES
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- C07K2317/77—Internalization into the cell
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Landscapes
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- Peptides Or Proteins (AREA)
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| CA2975228C (en) | 2008-05-02 | 2020-07-21 | Seattle Genetics, Inc. | Methods and compositions for making antibodies and antibody derivatives with reduced core fucosylation |
| CN103596979B (zh) * | 2011-03-16 | 2018-01-26 | 阿尔金-X有限公司 | 针对cd70的抗体 |
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| CA2910553A1 (en) * | 2013-04-30 | 2014-11-06 | Universite De Montreal | Novel biomarkers for acute myeloid leukemia |
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| US10391168B1 (en) * | 2014-08-22 | 2019-08-27 | University Of Bern | Anti-CD70 combination therapy |
| KR102390359B1 (ko) * | 2014-09-29 | 2022-04-22 | 삼성전자주식회사 | 폴리펩타이드, 이를 포함하는 항 VEGF 항체 및 항 c-Met/항 VEGF 이중 특이 항체 |
| US20180244792A1 (en) * | 2015-09-10 | 2018-08-30 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Anti-fibrotic effect of cd70 |
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| GB2567613A (en) * | 2017-06-16 | 2019-04-24 | Argenx Bvba | Treatment for acute myeloid leukaemia |
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| KR102780406B1 (ko) | 2018-02-01 | 2025-03-17 | 화이자 인코포레이티드 | Cd70을 표적으로 하는 키메라 항원 수용체 |
| PE20251579A1 (es) * | 2018-02-01 | 2025-06-16 | Pfizer | Anticuerpos especificos para cd70 y sus usos |
| CN112105420A (zh) | 2018-05-11 | 2020-12-18 | 克里斯珀医疗股份公司 | 用于治疗癌症的方法和组合物 |
| US20220047634A1 (en) * | 2018-11-30 | 2022-02-17 | Dana-Farber Cancer Institute, Inc. | Chimeric antigen receptor factories and methods of use thereof |
| TWI848030B (zh) | 2018-12-18 | 2024-07-11 | 比利時商阿根思公司 | Ｃｄ７０組合治療 |
| WO2020222176A1 (en) | 2019-04-30 | 2020-11-05 | Crispr Therapeutics Ag | Allogeneic cell therapy of b cell malignancies using genetically engineered t cells targeting cd19 |
| RU2738802C1 (ru) * | 2019-08-21 | 2020-12-17 | Общество с ограниченной ответственностью "Международный Биотехнологический Центр "Генериум" | Определяющие комплементарность участки для связывания cd3 и содержащая их биспецифическая антигенсвязывающая молекула |
| MX2022008485A (es) * | 2020-01-08 | 2022-08-02 | Univ Texas | Un metodo para modificar celulas asesinas naturales para dirigirse a tumores positivos a cd70. |
| CN111909966B (zh) * | 2020-04-01 | 2021-09-21 | 苏州克睿基因生物科技有限公司 | 一种制备经修饰的免疫细胞的方法 |
| CA3185846A1 (en) * | 2020-06-30 | 2022-01-06 | Jiangsu Hengrui Pharmaceuticals Co., Ltd. | Anti-cd70 antibody and application thereof |
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| CN114685657B (zh) * | 2020-12-31 | 2024-08-16 | 康诺亚生物医药科技（成都）有限公司 | 一种功能增强型抗体阻断剂的开发及其应用 |
| CN115260303B (zh) * | 2021-05-31 | 2025-04-22 | 百奥赛图(北京)医药科技股份有限公司 | Cd70基因人源化非人动物的构建方法及应用 |
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| CN113754769B (zh) * | 2021-10-13 | 2023-06-06 | 宜明昂科生物医药技术（上海）股份有限公司 | 靶向cd70的抗体及其制备和用途 |
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