TR200101628T2 - Hidroksibenzo[b]tiofen-3-karboksilik asit türevlerinin hazırlanması - Google Patents
Hidroksibenzo[b]tiofen-3-karboksilik asit türevlerinin hazırlanmasıInfo
- Publication number
- TR200101628T2 TR200101628T2 TR2001/01628T TR200101628T TR200101628T2 TR 200101628 T2 TR200101628 T2 TR 200101628T2 TR 2001/01628 T TR2001/01628 T TR 2001/01628T TR 200101628 T TR200101628 T TR 200101628T TR 200101628 T2 TR200101628 T2 TR 200101628T2
- Authority
- TR
- Turkey
- Prior art keywords
- acid derivatives
- hydroxybenzo
- thiophene
- preparation
- carboxylic acid
- Prior art date
Links
- GFIVCNPIBULNQF-UHFFFAOYSA-N 2-hydroxy-1-benzothiophene-3-carboxylic acid Chemical class C1=CC=C2C(C(=O)O)=C(O)SC2=C1 GFIVCNPIBULNQF-UHFFFAOYSA-N 0.000 title 1
- DYSJMQABFPKAQM-UHFFFAOYSA-N 1-benzothiophene-2-carboxylic acid Chemical class C1=CC=C2SC(C(=O)O)=CC2=C1 DYSJMQABFPKAQM-UHFFFAOYSA-N 0.000 abstract 1
- ZAZIPEFQVRYIGU-UHFFFAOYSA-N 5-hydroxy-1-benzothiophene-3-carboxylic acid Chemical class C1=C(O)C=C2C(C(=O)O)=CSC2=C1 ZAZIPEFQVRYIGU-UHFFFAOYSA-N 0.000 abstract 1
- 102100029100 Hematopoietic prostaglandin D synthase Human genes 0.000 abstract 1
- 101000988802 Homo sapiens Hematopoietic prostaglandin D synthase Proteins 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- BHMBVRSPMRCCGG-OUTUXVNYSA-N prostaglandin D2 Chemical compound CCCCC[C@H](O)\C=C\[C@@H]1[C@@H](C\C=C/CCCC(O)=O)[C@@H](O)CC1=O BHMBVRSPMRCCGG-OUTUXVNYSA-N 0.000 abstract 1
- BHMBVRSPMRCCGG-UHFFFAOYSA-N prostaglandine D2 Natural products CCCCCC(O)C=CC1C(CC=CCCCC(O)=O)C(O)CC1=O BHMBVRSPMRCCGG-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Ilaç yapiminda faydali olan benzotiofenkarboksilik asit türevleri ve spesifik PGD2 antagonistleri olan formül (VI) 5-hidroksibenzo[b]-tiofen-3-karboksilik asit türevlerinin hazirlanmasi için proses:FORMÜL VAR
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8581998 | 1998-03-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR200101628T2 true TR200101628T2 (tr) | 2002-07-22 |
Family
ID=13869477
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2000/02839T TR200002839T2 (tr) | 1998-03-31 | 1999-03-30 | 5-Hidroksibenzo[b]tiofen-3-karboksilik asit türevlerinin hazırlanması. |
| TR2001/01628T TR200101628T2 (tr) | 1998-03-31 | 1999-03-30 | Hidroksibenzo[b]tiofen-3-karboksilik asit türevlerinin hazırlanması |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2000/02839T TR200002839T2 (tr) | 1998-03-31 | 1999-03-30 | 5-Hidroksibenzo[b]tiofen-3-karboksilik asit türevlerinin hazırlanması. |
Country Status (20)
| Country | Link |
|---|---|
| US (3) | US6320060B1 (tr) |
| EP (2) | EP1528060A1 (tr) |
| JP (1) | JP3455181B2 (tr) |
| KR (1) | KR100596284B1 (tr) |
| CN (2) | CN1117743C (tr) |
| AT (1) | ATE298747T1 (tr) |
| AU (1) | AU745129B2 (tr) |
| BR (1) | BR9909290A (tr) |
| CA (1) | CA2326419A1 (tr) |
| DE (1) | DE69925992T2 (tr) |
| ES (1) | ES2244179T3 (tr) |
| HU (1) | HUP0101728A3 (tr) |
| ID (1) | ID26346A (tr) |
| NO (1) | NO20004919L (tr) |
| PL (2) | PL197331B1 (tr) |
| RU (1) | RU2186065C1 (tr) |
| TR (2) | TR200002839T2 (tr) |
| TW (1) | TWI247007B (tr) |
| WO (1) | WO1999050260A1 (tr) |
| ZA (1) | ZA200004720B (tr) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2769165B1 (fr) * | 1997-09-26 | 2002-11-29 | Technical Maintenance Corp | Systeme sans fil a transmission numerique pour haut-parleurs |
| US6051044A (en) | 1998-05-04 | 2000-04-18 | Cabot Corporation | Nitrided niobium powders and niobium electrolytic capacitors |
| DE60039876D1 (de) | 1999-07-02 | 2008-09-25 | Shionogi & Co | Neuartiges verfahren zur herstellung bicyclischer amino-alkohole |
| WO2002042289A2 (en) * | 2000-11-27 | 2002-05-30 | Eli Lilly And Company | Process for preparing 3-aryl-benzo[b]thiophenes |
| US20050192271A1 (en) * | 2003-07-15 | 2005-09-01 | Hythiam, Inc. | Use of selective chloride channel modulators to treat alcohol and/or stimulant substance abuse |
| EP1298130B1 (en) * | 2001-05-07 | 2008-08-13 | Teijin Pharma Limited | 3-hydroxymethylbenzo b thiophene derivatives and process for their preparation |
| US6727277B1 (en) | 2002-11-12 | 2004-04-27 | Kansas State University Research Foundation | Compounds affecting cholesterol absorption |
| KR20070002085A (ko) * | 2004-04-07 | 2007-01-04 | 밀레니엄 파머슈티컬스 인코퍼레이티드 | 염증 질병을 치료하기 위한 ｐｇｄ２ 수용체 길항제 |
| JO3598B1 (ar) * | 2006-10-10 | 2020-07-05 | Infinity Discovery Inc | الاحماض والاسترات البورونية كمثبطات اميد هيدروليز الحامض الدهني |
| WO2011106529A2 (en) * | 2010-02-24 | 2011-09-01 | Wherepro, Llc | Data packet generator and implementations of same |
| RU2722595C1 (ru) * | 2019-12-27 | 2020-06-02 | Федеральное государственное бюджетное учреждение науки институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова Российской академии наук (ИБХ РАН) | Способ получения сложного эфира 4-формил-6,7-дигидрокси-бензо[b]тиофен-3-карбоновой кислоты |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE809894A (nl) * | 1973-01-30 | 1974-07-18 | Antikleursluierstoffen voor fotografische kleurenmaterialen | |
| NZ218115A (en) * | 1985-11-18 | 1990-02-26 | Shionogi & Co | Bicyclic sulphonamides and pharmaceutical compositions |
| CA1294974C (en) * | 1987-05-08 | 1992-01-28 | Sanji Hagishita | Bicyclic sulfonamide derivatives and process therefor |
| ES2270438T3 (es) * | 1995-06-21 | 2007-04-01 | SHIONOGI & CO., LTD. | Derivados amino biciclicos y agonista de pgd2 que contienen los mismos. |
| GB9513467D0 (en) | 1995-07-01 | 1995-09-06 | Knoll Ag | Therapeutic agents |
| CZ297324B6 (cs) * | 1996-12-13 | 2006-11-15 | Shionogi & Co., Ltd. | Benzothiofenkarboxamidové deriváty a antagonisty PGD2, které je obsahují |
-
1999
- 1999-03-30 AT AT99910764T patent/ATE298747T1/de not_active IP Right Cessation
- 1999-03-30 TW TW088105047A patent/TWI247007B/zh not_active IP Right Cessation
- 1999-03-30 JP JP2000541164A patent/JP3455181B2/ja not_active Expired - Fee Related
- 1999-03-30 ES ES99910764T patent/ES2244179T3/es not_active Expired - Lifetime
- 1999-03-30 HU HU0101728A patent/HUP0101728A3/hu unknown
- 1999-03-30 WO PCT/JP1999/001616 patent/WO1999050260A1/ja active IP Right Grant
- 1999-03-30 DE DE69925992T patent/DE69925992T2/de not_active Expired - Fee Related
- 1999-03-30 TR TR2000/02839T patent/TR200002839T2/tr unknown
- 1999-03-30 PL PL380954A patent/PL197331B1/pl unknown
- 1999-03-30 EP EP04026501A patent/EP1528060A1/en not_active Withdrawn
- 1999-03-30 CA CA002326419A patent/CA2326419A1/en not_active Abandoned
- 1999-03-30 KR KR1020007010877A patent/KR100596284B1/ko not_active IP Right Cessation
- 1999-03-30 ID IDW20002020A patent/ID26346A/id unknown
- 1999-03-30 CN CN99804788A patent/CN1117743C/zh not_active Expired - Fee Related
- 1999-03-30 AU AU29601/99A patent/AU745129B2/en not_active Ceased
- 1999-03-30 BR BR9909290-5A patent/BR9909290A/pt not_active Application Discontinuation
- 1999-03-30 RU RU2000127108/04A patent/RU2186065C1/ru not_active IP Right Cessation
- 1999-03-30 TR TR2001/01628T patent/TR200101628T2/tr unknown
- 1999-03-30 PL PL99343316A patent/PL343316A1/xx not_active IP Right Cessation
- 1999-03-30 EP EP99910764A patent/EP1069122B1/en not_active Expired - Lifetime
- 1999-03-30 US US09/647,354 patent/US6320060B1/en not_active Expired - Fee Related
-
2000
- 2000-09-07 ZA ZA200004720A patent/ZA200004720B/xx unknown
- 2000-09-29 NO NO20004919A patent/NO20004919L/no not_active Application Discontinuation
-
2001
- 2001-09-26 US US09/962,439 patent/US6495702B2/en not_active Expired - Fee Related
- 2001-09-26 US US09/962,189 patent/US6346628B1/en not_active Expired - Fee Related
-
2003
- 2003-01-21 CN CNB031035337A patent/CN1249048C/zh not_active Expired - Fee Related
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