TR200101628T2 - Hidroksibenzo[b]tiofen-3-karboksilik asit türevlerinin hazırlanması - Google Patents
Hidroksibenzo[b]tiofen-3-karboksilik asit türevlerinin hazırlanmasıInfo
- Publication number
- TR200101628T2 TR200101628T2 TR2001/01628T TR200101628T TR200101628T2 TR 200101628 T2 TR200101628 T2 TR 200101628T2 TR 2001/01628 T TR2001/01628 T TR 2001/01628T TR 200101628 T TR200101628 T TR 200101628T TR 200101628 T2 TR200101628 T2 TR 200101628T2
- Authority
- TR
- Turkey
- Prior art keywords
- acid derivatives
- hydroxybenzo
- thiophene
- preparation
- carboxylic acid
- Prior art date
Links
- GFIVCNPIBULNQF-UHFFFAOYSA-N 2-hydroxy-1-benzothiophene-3-carboxylic acid Chemical class C1=CC=C2C(C(=O)O)=C(O)SC2=C1 GFIVCNPIBULNQF-UHFFFAOYSA-N 0.000 title 1
- DYSJMQABFPKAQM-UHFFFAOYSA-N 1-benzothiophene-2-carboxylic acid Chemical class C1=CC=C2SC(C(=O)O)=CC2=C1 DYSJMQABFPKAQM-UHFFFAOYSA-N 0.000 abstract 1
- ZAZIPEFQVRYIGU-UHFFFAOYSA-N 5-hydroxy-1-benzothiophene-3-carboxylic acid Chemical class C1=C(O)C=C2C(C(=O)O)=CSC2=C1 ZAZIPEFQVRYIGU-UHFFFAOYSA-N 0.000 abstract 1
- 102100029100 Hematopoietic prostaglandin D synthase Human genes 0.000 abstract 1
- 101000988802 Homo sapiens Hematopoietic prostaglandin D synthase Proteins 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- BHMBVRSPMRCCGG-OUTUXVNYSA-N prostaglandin D2 Chemical compound CCCCC[C@H](O)\C=C\[C@@H]1[C@@H](C\C=C/CCCC(O)=O)[C@@H](O)CC1=O BHMBVRSPMRCCGG-OUTUXVNYSA-N 0.000 abstract 1
- BHMBVRSPMRCCGG-UHFFFAOYSA-N prostaglandine D2 Natural products CCCCCC(O)C=CC1C(CC=CCCCC(O)=O)C(O)CC1=O BHMBVRSPMRCCGG-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Ilaç yapiminda faydali olan benzotiofenkarboksilik asit türevleri ve spesifik PGD2 antagonistleri olan formül (VI) 5-hidroksibenzo[b]-tiofen-3-karboksilik asit türevlerinin hazirlanmasi için proses:FORMÜL VAR
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8581998 | 1998-03-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR200101628T2 true TR200101628T2 (tr) | 2002-07-22 |
Family
ID=13869477
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2000/02839T TR200002839T2 (tr) | 1998-03-31 | 1999-03-30 | 5-Hidroksibenzo[b]tiofen-3-karboksilik asit türevlerinin hazırlanması. |
| TR2001/01628T TR200101628T2 (tr) | 1998-03-31 | 1999-03-30 | Hidroksibenzo[b]tiofen-3-karboksilik asit türevlerinin hazırlanması |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2000/02839T TR200002839T2 (tr) | 1998-03-31 | 1999-03-30 | 5-Hidroksibenzo[b]tiofen-3-karboksilik asit türevlerinin hazırlanması. |
Country Status (20)
| Country | Link |
|---|---|
| US (3) | US6320060B1 (tr) |
| EP (2) | EP1069122B1 (tr) |
| JP (1) | JP3455181B2 (tr) |
| KR (1) | KR100596284B1 (tr) |
| CN (2) | CN1117743C (tr) |
| AT (1) | ATE298747T1 (tr) |
| AU (1) | AU745129B2 (tr) |
| BR (1) | BR9909290A (tr) |
| CA (1) | CA2326419A1 (tr) |
| DE (1) | DE69925992T2 (tr) |
| ES (1) | ES2244179T3 (tr) |
| HU (1) | HUP0101728A3 (tr) |
| ID (1) | ID26346A (tr) |
| NO (1) | NO20004919L (tr) |
| PL (2) | PL343316A1 (tr) |
| RU (1) | RU2186065C1 (tr) |
| TR (2) | TR200002839T2 (tr) |
| TW (1) | TWI247007B (tr) |
| WO (1) | WO1999050260A1 (tr) |
| ZA (1) | ZA200004720B (tr) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2769165B1 (fr) * | 1997-09-26 | 2002-11-29 | Technical Maintenance Corp | Systeme sans fil a transmission numerique pour haut-parleurs |
| US6051044A (en) | 1998-05-04 | 2000-04-18 | Cabot Corporation | Nitrided niobium powders and niobium electrolytic capacitors |
| EP1193243B1 (en) | 1999-07-02 | 2008-08-13 | Shionogi & Co., Ltd. | Novel process for producing bicyclic amino alcohol |
| AU2002230409A1 (en) * | 2000-11-27 | 2002-06-03 | Eli Lilly And Company | Process for preparing 3-aryl-benzo(b)thiophenes |
| US20050192271A1 (en) * | 2003-07-15 | 2005-09-01 | Hythiam, Inc. | Use of selective chloride channel modulators to treat alcohol and/or stimulant substance abuse |
| JP3999131B2 (ja) * | 2001-05-07 | 2007-10-31 | 帝人株式会社 | ３−ヒドロキシメチル−ベンゾ［ｂ］チオフェン誘導体、及びその製造方法 |
| US6727277B1 (en) | 2002-11-12 | 2004-04-27 | Kansas State University Research Foundation | Compounds affecting cholesterol absorption |
| AR048528A1 (es) * | 2004-04-07 | 2006-05-03 | Millennium Pharm Inc | Compuestos derivados de quinolina como antagonistas del receptor de pgd2 para el tratamiento de enfermedades inflamatorias y composiciones farmacéuticas que los contienen. |
| JO3598B1 (ar) * | 2006-10-10 | 2020-07-05 | Infinity Discovery Inc | الاحماض والاسترات البورونية كمثبطات اميد هيدروليز الحامض الدهني |
| US20110244798A1 (en) * | 2010-02-24 | 2011-10-06 | Wherepro, Llc | Data Packet Generator and Implementations of Same |
| RU2722595C1 (ru) * | 2019-12-27 | 2020-06-02 | Федеральное государственное бюджетное учреждение науки институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова Российской академии наук (ИБХ РАН) | Способ получения сложного эфира 4-формил-6,7-дигидрокси-бензо[b]тиофен-3-карбоновой кислоты |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE809894A (nl) * | 1973-01-30 | 1974-07-18 | Antikleursluierstoffen voor fotografische kleurenmaterialen | |
| NZ218115A (en) * | 1985-11-18 | 1990-02-26 | Shionogi & Co | Bicyclic sulphonamides and pharmaceutical compositions |
| CA1294974C (en) * | 1987-05-08 | 1992-01-28 | Sanji Hagishita | Bicyclic sulfonamide derivatives and process therefor |
| CZ285870B6 (cs) * | 1995-06-21 | 1999-11-17 | Shionogi & Co., Ltd. | Bicyklické aminoderiváty a antagonist PGD2, který je obsahuje |
| GB9513467D0 (en) * | 1995-07-01 | 1995-09-06 | Knoll Ag | Therapeutic agents |
| AU718958B2 (en) * | 1996-12-13 | 2000-05-04 | Shionogi & Co., Ltd. | Benzothiophenecarboxamide derivatives and PGD2 antagonists comprising them |
-
1999
- 1999-03-30 AT AT99910764T patent/ATE298747T1/de not_active IP Right Cessation
- 1999-03-30 AU AU29601/99A patent/AU745129B2/en not_active Ceased
- 1999-03-30 BR BR9909290-5A patent/BR9909290A/pt not_active Application Discontinuation
- 1999-03-30 TR TR2000/02839T patent/TR200002839T2/tr unknown
- 1999-03-30 TR TR2001/01628T patent/TR200101628T2/tr unknown
- 1999-03-30 RU RU2000127108/04A patent/RU2186065C1/ru not_active IP Right Cessation
- 1999-03-30 ES ES99910764T patent/ES2244179T3/es not_active Expired - Lifetime
- 1999-03-30 HU HU0101728A patent/HUP0101728A3/hu unknown
- 1999-03-30 ID IDW20002020A patent/ID26346A/id unknown
- 1999-03-30 EP EP99910764A patent/EP1069122B1/en not_active Expired - Lifetime
- 1999-03-30 EP EP04026501A patent/EP1528060A1/en not_active Withdrawn
- 1999-03-30 CN CN99804788A patent/CN1117743C/zh not_active Expired - Fee Related
- 1999-03-30 PL PL99343316A patent/PL343316A1/xx not_active IP Right Cessation
- 1999-03-30 PL PL380954A patent/PL197331B1/pl unknown
- 1999-03-30 JP JP2000541164A patent/JP3455181B2/ja not_active Expired - Fee Related
- 1999-03-30 TW TW088105047A patent/TWI247007B/zh not_active IP Right Cessation
- 1999-03-30 US US09/647,354 patent/US6320060B1/en not_active Expired - Fee Related
- 1999-03-30 DE DE69925992T patent/DE69925992T2/de not_active Expired - Fee Related
- 1999-03-30 WO PCT/JP1999/001616 patent/WO1999050260A1/ja active IP Right Grant
- 1999-03-30 CA CA002326419A patent/CA2326419A1/en not_active Abandoned
- 1999-03-30 KR KR1020007010877A patent/KR100596284B1/ko not_active IP Right Cessation
-
2000
- 2000-09-07 ZA ZA200004720A patent/ZA200004720B/xx unknown
- 2000-09-29 NO NO20004919A patent/NO20004919L/no not_active Application Discontinuation
-
2001
- 2001-09-26 US US09/962,189 patent/US6346628B1/en not_active Expired - Fee Related
- 2001-09-26 US US09/962,439 patent/US6495702B2/en not_active Expired - Fee Related
-
2003
- 2003-01-21 CN CNB031035337A patent/CN1249048C/zh not_active Expired - Fee Related
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