TR200100631T2 - Peptit-olmayan GnRH maddeleri - Google Patents
Peptit-olmayan GnRH maddeleriInfo
- Publication number
- TR200100631T2 TR200100631T2 TR2001/00631T TR200100631T TR200100631T2 TR 200100631 T2 TR200100631 T2 TR 200100631T2 TR 2001/00631 T TR2001/00631 T TR 2001/00631T TR 200100631 T TR200100631 T TR 200100631T TR 200100631 T2 TR200100631 T2 TR 200100631T2
- Authority
- TR
- Turkey
- Prior art keywords
- substances
- peptide gnrh
- gonadotropin
- compounds
- peptide
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/16—Masculine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
- A61P5/04—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin for decreasing, blocking or antagonising the activity of the hypothalamic hormones
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/14—Radicals substituted by nitrogen atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/26—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/12—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/10—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/14—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Reproductive Health (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Gonadotropin saliveren hormonun etkisini önleyebilen peptit olmayan GnRH maddeleri tarif edilmektedir. Bu bilesikler ve bunlarin farmasötik açidan kabul gören tuzlari, ön ilaçlari ve aktif metabolitleri, memelilerde yeniden üretici bozukuluklarin ve steroid hormonuna bagli tümörlerin tedavi edilmesinin yani sira gonadotropin saliverilmesinin bastirilmasini isaret eden yerde üremenin düzenlenmesi için uygundur. Preparasyonda faydali bilesiklerin ve ara baglarin sentezlenmesine yönelik metotlar da tarif edilmektedir.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9752098P | 1998-08-20 | 1998-08-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
TR200100631T2 true TR200100631T2 (tr) | 2002-08-21 |
Family
ID=22263796
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2001/00631T TR200100631T2 (tr) | 1998-08-20 | 1999-08-20 | Peptit-olmayan GnRH maddeleri |
Country Status (33)
Country | Link |
---|---|
EP (1) | EP1105120B1 (tr) |
JP (1) | JP2002535244A (tr) |
KR (1) | KR20010085402A (tr) |
CN (1) | CN1379666A (tr) |
AP (1) | AP2001002053A0 (tr) |
AT (1) | ATE291423T1 (tr) |
AU (1) | AU759310B2 (tr) |
BG (1) | BG105362A (tr) |
BR (1) | BR9913374A (tr) |
CA (1) | CA2341346A1 (tr) |
CZ (1) | CZ2001523A3 (tr) |
DE (1) | DE69924387D1 (tr) |
EA (1) | EA200100255A1 (tr) |
EE (1) | EE200100102A (tr) |
ES (1) | ES2237966T3 (tr) |
GE (1) | GEP20043315B (tr) |
HR (1) | HRP20010206A2 (tr) |
HU (1) | HUP0103622A3 (tr) |
ID (1) | ID29244A (tr) |
IL (1) | IL141396A0 (tr) |
IS (1) | IS5846A (tr) |
LT (1) | LT4904B (tr) |
LV (1) | LV12732B (tr) |
NO (1) | NO20010309L (tr) |
NZ (1) | NZ509252A (tr) |
OA (1) | OA11599A (tr) |
PL (1) | PL356984A1 (tr) |
SI (1) | SI20746A (tr) |
SK (1) | SK2262001A3 (tr) |
TR (1) | TR200100631T2 (tr) |
WO (1) | WO2000020358A2 (tr) |
YU (1) | YU13701A (tr) |
ZA (1) | ZA200100831B (tr) |
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ATE195716T1 (de) * | 1992-04-22 | 2000-09-15 | Ligand Pharm Inc | Retinoid-x rezeptor selektive verbindungen |
HUP0200761A3 (en) * | 1999-03-24 | 2003-05-28 | Anormed Inc Langley | Chemokine receptor binding heterocyclic compounds, pharmaceutical compositions containing them and their use |
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JP2005501006A (ja) * | 2001-06-06 | 2005-01-13 | アグロン・ファーマシューティカルズ・インコーポレーテッド | 非ペプチドGnRH薬、医薬組成物、その利用法、これら物質とその中間体の調製方法 |
KR100900304B1 (ko) * | 2001-06-11 | 2009-06-02 | 바이로켐 파마 인코포레이티드 | 플라비 바이러스 감염용 항바이러스제로서의 티오펜 유도체 |
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ATE334687T1 (de) * | 2002-11-20 | 2006-08-15 | Paradigm Therapeutics Ltd | Heterozyklische siliziumverbindungen und deren verwendung zur behandlung von krankheiten oder zuständen, die mit gonadotropin-freisetzenden hormon assoziiert sind |
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US20050004133A1 (en) * | 2003-06-05 | 2005-01-06 | Makings Lewis R. | Modulators of VR1 receptor |
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CA2531511A1 (en) * | 2003-07-10 | 2005-01-20 | Paradigm Therapeutics Ltd. | Silicon compounds and their use |
WO2005039564A1 (en) * | 2003-10-02 | 2005-05-06 | Vertex Pharmaceuticals Incorporated | Phthalimide compounds useful as protein kinase inhibitors |
US20090291915A1 (en) * | 2004-12-17 | 2009-11-26 | Graham Andrew Showell | Silicon Compounds and Their Use |
CN101218224B (zh) | 2005-05-13 | 2013-05-08 | Viro化学制药公司 | 治疗或预防黄病毒感染的组合物和方法 |
CA2612227C (en) | 2005-06-14 | 2014-04-22 | Taigen Biotechnology Co., Ltd. | Pyrimidine compounds |
US8193206B2 (en) | 2005-06-14 | 2012-06-05 | Taigen Biotechnology Co., Ltd. | Pyrimidine compounds |
JP2008543965A (ja) * | 2005-06-28 | 2008-12-04 | タケダ・ケンブリッジ・リミテッド | 複素環式非ペプチドgnrh拮抗薬 |
CA2617532A1 (en) * | 2005-08-04 | 2007-02-15 | Sirtris Pharmaceuticals, Inc. | Imidazo [2,1-b] thiazole derivatives as sirtuin modulating compounds |
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EP2227453B1 (en) * | 2007-10-11 | 2016-03-09 | Vertex Pharmaceuticals Incorporated | Heteroaryl amides useful as inhibitors of voltage-gated sodium channels |
CA2703684A1 (en) | 2007-10-31 | 2009-05-07 | Research Foundation Itsuu Laboratory | Retinoid prodrug compound |
KR101579999B1 (ko) | 2008-04-21 | 2015-12-23 | 타이젠 바이오테크놀러지 컴퍼니 리미티드 | 헤테로사이클릭 화합물 |
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1999
- 1999-08-20 CZ CZ2001523A patent/CZ2001523A3/cs unknown
- 1999-08-20 NZ NZ509252A patent/NZ509252A/en unknown
- 1999-08-20 BR BR9913374-1A patent/BR9913374A/pt not_active IP Right Cessation
- 1999-08-20 SI SI9920076A patent/SI20746A/sl not_active IP Right Cessation
- 1999-08-20 CA CA002341346A patent/CA2341346A1/en not_active Abandoned
- 1999-08-20 EA EA200100255A patent/EA200100255A1/ru unknown
- 1999-08-20 AT AT99968010T patent/ATE291423T1/de not_active IP Right Cessation
- 1999-08-20 HU HU0103622A patent/HUP0103622A3/hu unknown
- 1999-08-20 EE EEP200100102A patent/EE200100102A/xx unknown
- 1999-08-20 KR KR1020017002021A patent/KR20010085402A/ko not_active Application Discontinuation
- 1999-08-20 CN CN99812285A patent/CN1379666A/zh active Pending
- 1999-08-20 TR TR2001/00631T patent/TR200100631T2/tr unknown
- 1999-08-20 AP APAP/P/2001/002053A patent/AP2001002053A0/en unknown
- 1999-08-20 ID IDW20010406A patent/ID29244A/id unknown
- 1999-08-20 OA OA1200100043A patent/OA11599A/en unknown
- 1999-08-20 JP JP2000574479A patent/JP2002535244A/ja active Pending
- 1999-08-20 DE DE69924387T patent/DE69924387D1/de not_active Expired - Fee Related
- 1999-08-20 GE GE4368A patent/GEP20043315B/en unknown
- 1999-08-20 ES ES99968010T patent/ES2237966T3/es not_active Expired - Lifetime
- 1999-08-20 IL IL14139699A patent/IL141396A0/xx unknown
- 1999-08-20 EP EP99968010A patent/EP1105120B1/en not_active Expired - Lifetime
- 1999-08-20 YU YU13701A patent/YU13701A/sh unknown
- 1999-08-20 PL PL99356984A patent/PL356984A1/xx unknown
- 1999-08-20 WO PCT/US1999/018790 patent/WO2000020358A2/en not_active Application Discontinuation
- 1999-08-20 SK SK226-2001A patent/SK2262001A3/sk unknown
- 1999-08-20 AU AU24709/00A patent/AU759310B2/en not_active Ceased
-
2001
- 2001-01-19 NO NO20010309A patent/NO20010309L/no not_active Application Discontinuation
- 2001-01-30 ZA ZA200100831A patent/ZA200100831B/en unknown
- 2001-02-16 IS IS5846A patent/IS5846A/is unknown
- 2001-03-16 LV LVP-01-45A patent/LV12732B/en unknown
- 2001-03-19 BG BG105362A patent/BG105362A/xx unknown
- 2001-03-19 LT LT2001024A patent/LT4904B/lt unknown
- 2001-03-20 HR HR20010206A patent/HRP20010206A2/hr not_active Application Discontinuation
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