TR200002077T2 - Yeni pentasakaritler ve bunların hazırlanışı için prosesler ile bunları içinde bulunduran farmasötik kompozisyonlar. - Google Patents

Yeni pentasakaritler ve bunların hazırlanışı için prosesler ile bunları içinde bulunduran farmasötik kompozisyonlar.

Info

Publication number
TR200002077T2
TR200002077T2 TR2000/02077T TR200002077T TR200002077T2 TR 200002077 T2 TR200002077 T2 TR 200002077T2 TR 2000/02077 T TR2000/02077 T TR 2000/02077T TR 200002077 T TR200002077 T TR 200002077T TR 200002077 T2 TR200002077 T2 TR 200002077T2
Authority
TR
Turkey
Prior art keywords
processes
preparation
pharmaceutical compositions
compositions containing
pentasaccharides
Prior art date
Application number
TR2000/02077T
Other languages
English (en)
Turkish (tr)
Inventor
Petitou Maurice
Original Assignee
Sanofi-Synthelabo
Akzo Nobell N..V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi-Synthelabo, Akzo Nobell N..V. filed Critical Sanofi-Synthelabo
Publication of TR200002077T2 publication Critical patent/TR200002077T2/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • C08B37/0078—Degradation products

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
TR2000/02077T 1998-01-19 1999-01-13 Yeni pentasakaritler ve bunların hazırlanışı için prosesler ile bunları içinde bulunduran farmasötik kompozisyonlar. TR200002077T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9800514A FR2773801B1 (fr) 1998-01-19 1998-01-19 Nouveaux pentasaccharides, procedes pour leurs preparations et compositions pharmaceutiques les contenant

Publications (1)

Publication Number Publication Date
TR200002077T2 true TR200002077T2 (tr) 2000-12-21

Family

ID=9521913

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2000/02077T TR200002077T2 (tr) 1998-01-19 1999-01-13 Yeni pentasakaritler ve bunların hazırlanışı için prosesler ile bunları içinde bulunduran farmasötik kompozisyonlar.

Country Status (38)

Country Link
US (1) US6670338B1 (https=)
EP (1) EP1049706B1 (https=)
JP (1) JP4695756B2 (https=)
KR (1) KR100533565B1 (https=)
CN (1) CN1172948C (https=)
AR (1) AR012779A1 (https=)
AT (1) ATE241637T1 (https=)
AU (1) AU744137B2 (https=)
BR (1) BR9907100B1 (https=)
CA (1) CA2318326C (https=)
CO (1) CO4970823A1 (https=)
CZ (1) CZ299817B6 (https=)
DE (1) DE69908298T2 (https=)
DK (1) DK1049706T3 (https=)
DZ (1) DZ2706A1 (https=)
EE (1) EE04194B1 (https=)
EG (1) EG23760A (https=)
ES (1) ES2200494T3 (https=)
FR (1) FR2773801B1 (https=)
GT (1) GT199900006A (https=)
HR (1) HRP20000479A8 (https=)
HU (1) HU228335B1 (https=)
IL (2) IL137240A0 (https=)
MY (1) MY125636A (https=)
NO (1) NO316894B1 (https=)
NZ (1) NZ505614A (https=)
PL (1) PL191098B1 (https=)
PT (1) PT1049706E (https=)
RU (1) RU2193040C2 (https=)
SA (1) SA99191114B1 (https=)
SI (1) SI1049706T1 (https=)
SK (1) SK284176B6 (https=)
TR (1) TR200002077T2 (https=)
TW (1) TW550267B (https=)
UA (1) UA61124C2 (https=)
UY (1) UY25357A1 (https=)
WO (1) WO1999036428A1 (https=)
ZA (1) ZA99357B (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2814463B1 (fr) * 2000-09-22 2002-11-15 Sanofi Synthelabo Nouveaux polysaccharides a activite antithrombotique comprenant au moins une liaison covalente avec la biotine ou un derive de la biotine
AU2003302238A1 (en) 2002-12-03 2004-06-23 Axys Pharmaceuticals, Inc. 2-(2-hydroxybiphenyl-3-yl)-1h-benzoimidazole-5-carboxamidine derivatives as factor viia inhibitors
CN103788141B (zh) * 2004-03-04 2016-08-17 普罗吉恩制药有限公司 硫酸化寡聚糖衍生物
CN100338084C (zh) * 2004-07-02 2007-09-19 北京大学 抑制异种器官移植免疫排斥反应的五糖抗原的合成方法
FR2874924B1 (fr) 2004-09-09 2006-12-01 Sanofi Aventis Sa Hexadecasaccharides biotinyles, leur preparation et leur utilisation therapeutique
TWI403334B (zh) * 2004-12-23 2013-08-01 Merck Sharp & Dohme 包含生物素殘基之抗血栓雙重抑制劑
TWI376234B (en) 2005-02-01 2012-11-11 Msd Oss Bv Conjugates of a polypeptide and an oligosaccharide
US20070191306A1 (en) * 2005-08-17 2007-08-16 Bristol-Myers Squibb Company FACTOR Xa INHIBITOR FORMULATION AND METHOD
EP1908768A1 (en) * 2006-10-05 2008-04-09 Endotis Pharma Anticoagulant compounds
WO2009155108A1 (en) 2008-05-30 2009-12-23 Momenta Pharmaceuticals, Inc. Saccharide structures and methods of making and using such structures
US20110150976A1 (en) * 2008-09-10 2011-06-23 Transpharma Medical Ltd. Transdermal delivery of oligosaccharides
CA2777099C (en) * 2009-07-31 2018-03-27 Reliable Biopharmaceutical Corporation Process for preparing fondaparinux sodium and intermediates useful in the synthesis thereof
US8420790B2 (en) 2009-10-30 2013-04-16 Reliable Biopharmaceutical Corporation Efficient and scalable process for the manufacture of Fondaparinux sodium
EP2721044B1 (en) 2011-06-17 2015-11-18 Carbomimetics Synthetic pentasaccharides having short half-life and high activity

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0300099A1 (en) * 1987-07-20 1989-01-25 Akzo N.V. New pentasaccharides
EP0454220B1 (en) * 1990-04-23 1993-08-18 Akzo Nobel N.V. Carbohydrate derivatives comprising a trisaccharide unit
IL102758A (en) * 1991-08-23 1997-03-18 Akzo Nv Glycosaminoglycanoid derivatives, their preparation and pharmaceutical compositions comprising them
FR2704226B1 (fr) * 1993-04-22 1995-07-21 Sanofi Elf 3-desoxy oligosaccharides, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
NZ264340A (en) * 1993-09-01 1995-04-27 Akzo Nobel Nv Bisconjugate comprising two saccharides and a spacer, use in pharmaceutical compositions
FR2751334B1 (fr) * 1996-07-19 1998-10-16 Sanofi Sa Polysaccharides synthetiques, procede pour leur preparation et compositions pharmaceutiques les contenant

Also Published As

Publication number Publication date
WO1999036428A1 (fr) 1999-07-22
ZA99357B (en) 2000-07-19
UY25357A1 (es) 2000-12-29
CA2318326C (en) 2010-07-06
HRP20000479B8 (hr) 2025-09-12
EP1049706B1 (fr) 2003-05-28
BR9907100A (pt) 2000-10-24
UA61124C2 (en) 2003-11-17
HRP20000479A8 (hr) 2025-09-12
SA99191114B1 (ar) 2006-10-11
CO4970823A1 (es) 2000-11-07
CN1293679A (zh) 2001-05-02
AU744137B2 (en) 2002-02-14
AU1974699A (en) 1999-08-02
CN1172948C (zh) 2004-10-27
NO20003661L (no) 2000-09-19
RU2193040C2 (ru) 2002-11-20
HU228335B1 (en) 2013-03-28
EE200000421A (et) 2001-12-17
ATE241637T1 (de) 2003-06-15
JP4695756B2 (ja) 2011-06-08
FR2773801B1 (fr) 2000-05-12
BR9907100B1 (pt) 2013-09-03
US6670338B1 (en) 2003-12-30
NZ505614A (en) 2003-02-28
FR2773801A1 (fr) 1999-07-23
PT1049706E (pt) 2003-09-30
DE69908298D1 (de) 2003-07-03
DE69908298T2 (de) 2004-04-01
KR20010034205A (ko) 2001-04-25
ES2200494T3 (es) 2004-03-01
PL341874A1 (en) 2001-05-07
DK1049706T3 (da) 2003-09-29
HUP0102042A3 (en) 2003-07-28
CZ20002636A3 (cs) 2000-11-15
EG23760A (en) 2007-08-08
NO20003661D0 (no) 2000-07-17
PL191098B1 (pl) 2006-03-31
EE04194B1 (et) 2003-12-15
AR012779A1 (es) 2000-11-08
HRP20000479B1 (hr) 2006-04-30
GT199900006A (es) 2000-07-12
KR100533565B1 (ko) 2005-12-06
SI1049706T1 (en) 2003-12-31
HK1029999A1 (zh) 2001-04-20
NO316894B1 (no) 2004-06-14
DZ2706A1 (fr) 2003-09-01
IL137240A (en) 2007-10-31
EP1049706A1 (fr) 2000-11-08
TW550267B (en) 2003-09-01
CA2318326A1 (en) 1999-07-22
MY125636A (en) 2006-08-30
HUP0102042A1 (hu) 2001-10-28
HRP20000479A2 (en) 2001-02-28
EE200000421A1 (et) 2003-06-16
IL137240A0 (en) 2001-07-24
SK10792000A3 (sk) 2001-01-18
CZ299817B6 (cs) 2008-12-03
JP2002509154A (ja) 2002-03-26
SK284176B6 (sk) 2004-10-05

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