KR100533565B1 - 신규한 오당류, 이의 제조방법 및 이를 포함하는 제약 조성물 - Google Patents
신규한 오당류, 이의 제조방법 및 이를 포함하는 제약 조성물 Download PDFInfo
- Publication number
- KR100533565B1 KR100533565B1 KR10-2000-7007850A KR20007007850A KR100533565B1 KR 100533565 B1 KR100533565 B1 KR 100533565B1 KR 20007007850 A KR20007007850 A KR 20007007850A KR 100533565 B1 KR100533565 B1 KR 100533565B1
- Authority
- KR
- South Korea
- Prior art keywords
- methyl
- tri
- sulfo
- glucopyranosyl
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
- C08B37/0078—Degradation products
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Crystallography & Structural Chemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Polymers & Plastics (AREA)
- Materials Engineering (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9800514A FR2773801B1 (fr) | 1998-01-19 | 1998-01-19 | Nouveaux pentasaccharides, procedes pour leurs preparations et compositions pharmaceutiques les contenant |
| FR98/00514 | 1998-01-19 | ||
| PCT/FR1999/000045 WO1999036428A1 (fr) | 1998-01-19 | 1999-01-13 | Nouveaux pentasaccharides, procedes pour leurs preparations et compositions pharmaceutiques les contenant |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20010034205A KR20010034205A (ko) | 2001-04-25 |
| KR100533565B1 true KR100533565B1 (ko) | 2005-12-06 |
Family
ID=9521913
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR10-2000-7007850A Expired - Fee Related KR100533565B1 (ko) | 1998-01-19 | 1999-01-13 | 신규한 오당류, 이의 제조방법 및 이를 포함하는 제약 조성물 |
Country Status (38)
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2814463B1 (fr) * | 2000-09-22 | 2002-11-15 | Sanofi Synthelabo | Nouveaux polysaccharides a activite antithrombotique comprenant au moins une liaison covalente avec la biotine ou un derive de la biotine |
| AU2003302238A1 (en) | 2002-12-03 | 2004-06-23 | Axys Pharmaceuticals, Inc. | 2-(2-hydroxybiphenyl-3-yl)-1h-benzoimidazole-5-carboxamidine derivatives as factor viia inhibitors |
| CN103788141B (zh) * | 2004-03-04 | 2016-08-17 | 普罗吉恩制药有限公司 | 硫酸化寡聚糖衍生物 |
| CN100338084C (zh) * | 2004-07-02 | 2007-09-19 | 北京大学 | 抑制异种器官移植免疫排斥反应的五糖抗原的合成方法 |
| FR2874924B1 (fr) | 2004-09-09 | 2006-12-01 | Sanofi Aventis Sa | Hexadecasaccharides biotinyles, leur preparation et leur utilisation therapeutique |
| TWI403334B (zh) * | 2004-12-23 | 2013-08-01 | Merck Sharp & Dohme | 包含生物素殘基之抗血栓雙重抑制劑 |
| TWI376234B (en) | 2005-02-01 | 2012-11-11 | Msd Oss Bv | Conjugates of a polypeptide and an oligosaccharide |
| US20070191306A1 (en) * | 2005-08-17 | 2007-08-16 | Bristol-Myers Squibb Company | FACTOR Xa INHIBITOR FORMULATION AND METHOD |
| EP1908768A1 (en) * | 2006-10-05 | 2008-04-09 | Endotis Pharma | Anticoagulant compounds |
| WO2009155108A1 (en) | 2008-05-30 | 2009-12-23 | Momenta Pharmaceuticals, Inc. | Saccharide structures and methods of making and using such structures |
| US20110150976A1 (en) * | 2008-09-10 | 2011-06-23 | Transpharma Medical Ltd. | Transdermal delivery of oligosaccharides |
| CA2777099C (en) * | 2009-07-31 | 2018-03-27 | Reliable Biopharmaceutical Corporation | Process for preparing fondaparinux sodium and intermediates useful in the synthesis thereof |
| US8420790B2 (en) | 2009-10-30 | 2013-04-16 | Reliable Biopharmaceutical Corporation | Efficient and scalable process for the manufacture of Fondaparinux sodium |
| EP2721044B1 (en) | 2011-06-17 | 2015-11-18 | Carbomimetics | Synthetic pentasaccharides having short half-life and high activity |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0300099A1 (en) * | 1987-07-20 | 1989-01-25 | Akzo N.V. | New pentasaccharides |
| EP0454220B1 (en) * | 1990-04-23 | 1993-08-18 | Akzo Nobel N.V. | Carbohydrate derivatives comprising a trisaccharide unit |
| IL102758A (en) * | 1991-08-23 | 1997-03-18 | Akzo Nv | Glycosaminoglycanoid derivatives, their preparation and pharmaceutical compositions comprising them |
| FR2704226B1 (fr) * | 1993-04-22 | 1995-07-21 | Sanofi Elf | 3-desoxy oligosaccharides, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent. |
| NZ264340A (en) * | 1993-09-01 | 1995-04-27 | Akzo Nobel Nv | Bisconjugate comprising two saccharides and a spacer, use in pharmaceutical compositions |
| FR2751334B1 (fr) * | 1996-07-19 | 1998-10-16 | Sanofi Sa | Polysaccharides synthetiques, procede pour leur preparation et compositions pharmaceutiques les contenant |
-
1998
- 1998-01-19 FR FR9800514A patent/FR2773801B1/fr not_active Expired - Lifetime
-
1999
- 1999-01-13 DZ DZ990007A patent/DZ2706A1/xx active
- 1999-01-13 EP EP99900525A patent/EP1049706B1/fr not_active Expired - Lifetime
- 1999-01-13 WO PCT/FR1999/000045 patent/WO1999036428A1/fr not_active Ceased
- 1999-01-13 UA UA2000074112A patent/UA61124C2/xx unknown
- 1999-01-13 CN CNB998041386A patent/CN1172948C/zh not_active Expired - Fee Related
- 1999-01-13 IL IL13724099A patent/IL137240A0/xx active IP Right Grant
- 1999-01-13 SK SK1079-2000A patent/SK284176B6/sk not_active IP Right Cessation
- 1999-01-13 NZ NZ505614A patent/NZ505614A/xx not_active IP Right Cessation
- 1999-01-13 EE EEP200000421A patent/EE04194B1/xx unknown
- 1999-01-13 AU AU19746/99A patent/AU744137B2/en not_active Ceased
- 1999-01-13 ES ES99900525T patent/ES2200494T3/es not_active Expired - Lifetime
- 1999-01-13 PL PL341874A patent/PL191098B1/pl unknown
- 1999-01-13 BR BRPI9907100-2B1A patent/BR9907100B1/pt not_active IP Right Cessation
- 1999-01-13 TR TR2000/02077T patent/TR200002077T2/xx unknown
- 1999-01-13 AT AT99900525T patent/ATE241637T1/de active
- 1999-01-13 JP JP2000540143A patent/JP4695756B2/ja not_active Expired - Fee Related
- 1999-01-13 PT PT99900525T patent/PT1049706E/pt unknown
- 1999-01-13 DK DK99900525T patent/DK1049706T3/da active
- 1999-01-13 SI SI9930357T patent/SI1049706T1/xx unknown
- 1999-01-13 CA CA2318326A patent/CA2318326C/en not_active Expired - Fee Related
- 1999-01-13 DE DE69908298T patent/DE69908298T2/de not_active Expired - Lifetime
- 1999-01-13 HU HU0102042A patent/HU228335B1/hu not_active IP Right Cessation
- 1999-01-13 KR KR10-2000-7007850A patent/KR100533565B1/ko not_active Expired - Fee Related
- 1999-01-13 CZ CZ20002636A patent/CZ299817B6/cs not_active IP Right Cessation
- 1999-01-13 US US09/600,516 patent/US6670338B1/en not_active Expired - Lifetime
- 1999-01-13 RU RU2000119750/04A patent/RU2193040C2/ru not_active IP Right Cessation
- 1999-01-16 EG EG5599A patent/EG23760A/xx active
- 1999-01-18 MY MYPI99000205A patent/MY125636A/en unknown
- 1999-01-18 TW TW088100711A patent/TW550267B/zh active
- 1999-01-18 AR ARP990100171A patent/AR012779A1/es active IP Right Grant
- 1999-01-18 UY UY25357A patent/UY25357A1/es not_active IP Right Cessation
- 1999-01-19 GT GT199900006A patent/GT199900006A/es unknown
- 1999-01-19 CO CO99002525A patent/CO4970823A1/es unknown
- 1999-01-19 ZA ZA9900357A patent/ZA99357B/xx unknown
- 1999-02-27 SA SA99191114A patent/SA99191114B1/ar unknown
-
2000
- 2000-07-10 IL IL137240A patent/IL137240A/en not_active IP Right Cessation
- 2000-07-17 NO NO20003661A patent/NO316894B1/no not_active IP Right Cessation
-
2001
- 2001-02-28 HR HRP20000479AA patent/HRP20000479A8/hr not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2000500807A (ja) | 合成ポリサッカライド、それらの製造法およびそれらを含む医薬組成物 | |
| JP3594990B2 (ja) | ３−デオキシオリゴ糖、その製造方法およびそれを含有する医薬組成物 | |
| KR100533565B1 (ko) | 신규한 오당류, 이의 제조방법 및 이를 포함하는 제약 조성물 | |
| KR100513196B1 (ko) | 합성 폴리사카라이드, 그의 제조 방법 및 그를 함유한제약 조성물 | |
| HU226685B1 (en) | Carbohydrate derivatives and pharmaceutical compns. contg. them | |
| JP3501813B2 (ja) | 合成ポリサッカライド、それらの製造法およびそれらを含む医薬組成物 | |
| HK1029999B (en) | New pentasaccharides, their methods of production and pharmaceutical compositions containing same | |
| HU227307B1 (en) | Intermediates for the preparation of 3-deoxy-oligosaccharides |
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|---|---|---|---|
| PA0105 | International application |
St.27 status event code: A-0-1-A10-A15-nap-PA0105 |
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| P11-X000 | Amendment of application requested |
St.27 status event code: A-2-2-P10-P11-nap-X000 |
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| P13-X000 | Application amended |
St.27 status event code: A-2-2-P10-P13-nap-X000 |
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| PG1501 | Laying open of application |
St.27 status event code: A-1-1-Q10-Q12-nap-PG1501 |
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St.27 status event code: A-2-2-P10-P11-nap-X000 |
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