TR199700453A2 - Orto-ikame edilmis benzoilguanidin'ler, bunlarin imal edilmesine mahsus usul, bunlarin ilaç ya da diyagnostik madde olarak kullanilmalari ve bunlari ihtive eden ilaç. - Google Patents
Orto-ikame edilmis benzoilguanidin'ler, bunlarin imal edilmesine mahsus usul, bunlarin ilaç ya da diyagnostik madde olarak kullanilmalari ve bunlari ihtive eden ilaç.Info
- Publication number
- TR199700453A2 TR199700453A2 TR97/00453A TR9700453A TR199700453A2 TR 199700453 A2 TR199700453 A2 TR 199700453A2 TR 97/00453 A TR97/00453 A TR 97/00453A TR 9700453 A TR9700453 A TR 9700453A TR 199700453 A2 TR199700453 A2 TR 199700453A2
- Authority
- TR
- Turkey
- Prior art keywords
- drug
- ortho
- manufacture
- diagnostic agent
- substituted benzoylguanidines
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
- C07C279/22—Y being a hydrogen or a carbon atom, e.g. benzoylguanidines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pyridine Compounds (AREA)
Abstract
Formül I'e göre olan orto-ikame edilmis benzoilguanidin'ler olup, ki formülde R(l) ila R(5) arasindaki tortular istemlerde belirtilen anlamlari tasimaktadir, kardiyoprotektif kompenentlere sahip antiaritmik ilaç olarak enfarktüs profilaksi ve enfarktüs ayrica angina pectoris tedavisi için kullanilmaya uygundur. Bunlar koruyucu sekilde isemik kaynakli hasarlarin olusumunda, özellikle de isemik kaynakli kalp ritm bozukluklarinin olusumundaki patofizyolojik gelismeleri önlemektedirler.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19622370A DE19622370A1 (de) | 1996-06-04 | 1996-06-04 | Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
Publications (1)
Publication Number | Publication Date |
---|---|
TR199700453A2 true TR199700453A2 (tr) | 1997-12-21 |
Family
ID=7796095
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR97/00453A TR199700453A2 (tr) | 1996-06-04 | 1997-06-02 | Orto-ikame edilmis benzoilguanidin'ler, bunlarin imal edilmesine mahsus usul, bunlarin ilaç ya da diyagnostik madde olarak kullanilmalari ve bunlari ihtive eden ilaç. |
Country Status (29)
Country | Link |
---|---|
US (1) | US6011063A (tr) |
EP (1) | EP0811610B1 (tr) |
JP (1) | JP4101904B2 (tr) |
KR (1) | KR980002019A (tr) |
CN (1) | CN1064956C (tr) |
AR (1) | AR008761A1 (tr) |
AT (1) | ATE209630T1 (tr) |
AU (1) | AU723665B2 (tr) |
BR (1) | BR9703440A (tr) |
CA (1) | CA2206758C (tr) |
CZ (1) | CZ289411B6 (tr) |
DE (2) | DE19622370A1 (tr) |
DK (1) | DK0811610T3 (tr) |
ES (1) | ES2166487T3 (tr) |
HR (1) | HRP970304B1 (tr) |
HU (1) | HUP9700989A3 (tr) |
ID (1) | ID17038A (tr) |
IL (1) | IL120988A0 (tr) |
MX (1) | MX9704094A (tr) |
NO (1) | NO310188B1 (tr) |
NZ (1) | NZ314973A (tr) |
PL (1) | PL185757B1 (tr) |
PT (1) | PT811610E (tr) |
RU (1) | RU2214397C2 (tr) |
SI (1) | SI0811610T1 (tr) |
SK (1) | SK282628B6 (tr) |
TR (1) | TR199700453A2 (tr) |
TW (1) | TW429243B (tr) |
ZA (1) | ZA974869B (tr) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6410563B1 (en) | 1999-12-22 | 2002-06-25 | Merck Frosst Canada & Co. | Substituted 8-arylquinoline phosphodiesterase-4 inhibitors |
MY123585A (en) | 2000-03-23 | 2006-05-31 | Merck Canada Inc | Tri-aryl-substituted-ethane pde4 inhibitors. |
US6639077B2 (en) | 2000-03-23 | 2003-10-28 | Merck Frosst Canada & Co. | Tri-aryl-substituted-ethane PDE4 inhibitors |
AU6196201A (en) | 2000-05-25 | 2001-12-03 | Merck Frosst Canada Inc | Fluoroalkoxy-substituted benzamide dichloropyridinyl n-oxide pde4 inhibitor |
US6740666B2 (en) | 2000-12-20 | 2004-05-25 | Merck & Co., Inc. | Substituted 8-arylquinoline phosphodiesterase-4 inhibitors |
DE60205899T2 (de) | 2001-05-24 | 2006-06-29 | Merck Frosst Canada & Co, Kirkland | 1-biaryl-1,8-naphthyridin-4-one als phosphodieseterase-inhibitoren |
JO2311B1 (en) | 2001-08-29 | 2005-09-12 | ميرك فروست كندا ليمتد | Alkyl inhibitors Ariel phosphodiesterase-4 |
JP4493341B2 (ja) | 2002-03-12 | 2010-06-30 | メルク・シャープ・エンド・ドーム・コーポレイション | 代謝型グルタメート受容体−5の二アリール置換テトラゾールモジュレータ |
GB0916163D0 (en) * | 2009-09-15 | 2009-10-28 | Shire Llc | Prodrugs of guanfacine |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0612723B1 (de) * | 1993-02-20 | 1997-08-27 | Hoechst Aktiengesellschaft | Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament, als Inhibitoren des zellulären Na+/H+-Austauschs oder als Diagnostikum sowie sie enthaltendes Medikament |
DE4318756A1 (de) * | 1993-06-05 | 1994-12-08 | Hoechst Ag | Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
DE4422685A1 (de) * | 1994-06-29 | 1996-01-04 | Hoechst Ag | Ortho-amino-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
-
1996
- 1996-06-04 DE DE19622370A patent/DE19622370A1/de not_active Withdrawn
-
1997
- 1997-05-22 AT AT97108258T patent/ATE209630T1/de not_active IP Right Cessation
- 1997-05-22 SI SI9730284T patent/SI0811610T1/xx unknown
- 1997-05-22 DK DK97108258T patent/DK0811610T3/da active
- 1997-05-22 PT PT97108258T patent/PT811610E/pt unknown
- 1997-05-22 DE DE59705495T patent/DE59705495D1/de not_active Expired - Lifetime
- 1997-05-22 EP EP97108258A patent/EP0811610B1/de not_active Expired - Lifetime
- 1997-05-22 ES ES97108258T patent/ES2166487T3/es not_active Expired - Lifetime
- 1997-05-30 NZ NZ314973A patent/NZ314973A/en unknown
- 1997-06-02 CN CN971054797A patent/CN1064956C/zh not_active Expired - Fee Related
- 1997-06-02 TR TR97/00453A patent/TR199700453A2/tr unknown
- 1997-06-02 TW TW086107502A patent/TW429243B/zh active
- 1997-06-02 AR ARP970102385A patent/AR008761A1/es unknown
- 1997-06-02 ID IDP971869A patent/ID17038A/id unknown
- 1997-06-02 SK SK696-97A patent/SK282628B6/sk unknown
- 1997-06-02 AU AU24650/97A patent/AU723665B2/en not_active Ceased
- 1997-06-02 CZ CZ19971696A patent/CZ289411B6/cs not_active IP Right Cessation
- 1997-06-03 US US08/868,077 patent/US6011063A/en not_active Expired - Lifetime
- 1997-06-03 IL IL12098897A patent/IL120988A0/xx unknown
- 1997-06-03 PL PL97320327A patent/PL185757B1/pl not_active IP Right Cessation
- 1997-06-03 NO NO19972527A patent/NO310188B1/no not_active IP Right Cessation
- 1997-06-03 HU HU9700989A patent/HUP9700989A3/hu unknown
- 1997-06-03 MX MX9704094A patent/MX9704094A/es unknown
- 1997-06-03 RU RU97109913/04A patent/RU2214397C2/ru not_active IP Right Cessation
- 1997-06-03 ZA ZA9704869A patent/ZA974869B/xx unknown
- 1997-06-03 JP JP14439397A patent/JP4101904B2/ja not_active Expired - Fee Related
- 1997-06-03 KR KR1019970022785A patent/KR980002019A/ko not_active Application Discontinuation
- 1997-06-03 HR HR970304A patent/HRP970304B1/xx not_active IP Right Cessation
- 1997-06-04 CA CA002206758A patent/CA2206758C/en not_active Expired - Fee Related
- 1997-06-04 BR BR9703440A patent/BR9703440A/pt not_active IP Right Cessation
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