ATE274904T1 - 4,5-dihydroxy-2-cyclopenten-1-on für die behandlung von diabetes mellitus - Google Patents
4,5-dihydroxy-2-cyclopenten-1-on für die behandlung von diabetes mellitusInfo
- Publication number
- ATE274904T1 ATE274904T1 AT98909738T AT98909738T ATE274904T1 AT E274904 T1 ATE274904 T1 AT E274904T1 AT 98909738 T AT98909738 T AT 98909738T AT 98909738 T AT98909738 T AT 98909738T AT E274904 T1 ATE274904 T1 AT E274904T1
- Authority
- AT
- Austria
- Prior art keywords
- cyclopenten
- dihydroxy
- diabetes mellitus
- treatment
- chem
- Prior art date
Links
- HLOLRONOOCGTRG-UHFFFAOYSA-N 4,5-dihydroxycyclopent-2-en-1-one Chemical compound OC1C=CC(=O)C1O HLOLRONOOCGTRG-UHFFFAOYSA-N 0.000 title abstract 2
- 206010012601 diabetes mellitus Diseases 0.000 title abstract 2
- 239000013543 active substance Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical group 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/57—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
- C07C323/58—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton
- C07C323/59—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton with acylated amino groups bound to the carbon skeleton
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/57—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
- C07C323/58—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
- C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
- C07C45/60—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in six-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/78—Separation; Purification; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
- C07C49/707—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups a keto group being part of a three- to five-membered ring
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Public Health (AREA)
- Polymers & Plastics (AREA)
- Nutrition Science (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9287097 | 1997-03-28 | ||
| JP11177397 | 1997-04-15 | ||
| JP15732497 | 1997-06-02 | ||
| JP16347397 | 1997-06-06 | ||
| JP28320497 | 1997-10-01 | ||
| JP36328197 | 1997-12-16 | ||
| PCT/JP1998/001151 WO1998043624A1 (fr) | 1997-03-28 | 1998-03-18 | Medicaments anti-diabetiques |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE274904T1 true ATE274904T1 (de) | 2004-09-15 |
Family
ID=27551886
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98909738T ATE274904T1 (de) | 1997-03-28 | 1998-03-18 | 4,5-dihydroxy-2-cyclopenten-1-on für die behandlung von diabetes mellitus |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6194467B1 (de) |
| EP (1) | EP0978278B1 (de) |
| JP (1) | JP3664737B2 (de) |
| KR (1) | KR100459581B1 (de) |
| CN (1) | CN1123339C (de) |
| AT (1) | ATE274904T1 (de) |
| AU (1) | AU736516B2 (de) |
| CA (1) | CA2285316A1 (de) |
| DE (1) | DE69825981T2 (de) |
| EA (1) | EA001763B1 (de) |
| ES (1) | ES2227811T3 (de) |
| TW (1) | TW515714B (de) |
| WO (1) | WO1998043624A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050020687A1 (en) * | 1996-01-14 | 2005-01-27 | Consiglio Nazionale Ricerche | Methods of treating inflammatory and viral disorders by administering cyclopentenone compounds |
| CA2285988A1 (en) | 1997-03-17 | 1998-09-24 | Nobuto Koyama | Antiviral agents |
| US6194467B1 (en) | 1997-03-28 | 2001-02-27 | Takara Shuzo Co., Ltd. | Diabetes remedies |
| US6284801B1 (en) | 1997-04-01 | 2001-09-04 | Takara Shuzo Co., Ltd. | Antirheumatic agents |
| EP1008345A4 (de) * | 1997-07-02 | 2000-09-13 | Takara Shuzo Co | Antiallergische mittel |
| CN1133611C (zh) | 1998-01-19 | 2004-01-07 | 宝酒造株式会社 | 具有细胞凋亡诱发能力的物质 |
| KR20010102134A (ko) * | 1999-02-19 | 2001-11-15 | 오미야 히사시 | 치료제 |
| AU3665700A (en) * | 1999-03-22 | 2000-10-09 | Charterhouse Therapeutics Ltd. | Chemical compounds and their uses |
| GB9929702D0 (en) * | 1999-12-16 | 2000-02-09 | Charterhouse Therapeutics Ltd | Chemical compounds and their uses |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2608089B2 (ja) * | 1988-03-09 | 1997-05-07 | 帝人株式会社 | ４−ヒドロキシ−２−シクロペンテノン類およびそれを含有する薬剤組成物 |
| JP2571950B2 (ja) * | 1988-03-11 | 1997-01-16 | 財団法人野口研究所 | シクロペンテノン誘導体及びその製造法 |
| JPH0768163B2 (ja) * | 1989-03-17 | 1995-07-26 | 財団法人野口研究所 | シクロペンテノン誘導体の製法 |
| WO1998013328A1 (fr) * | 1996-09-27 | 1998-04-02 | Takara Shuzo Co., Ltd. | Cyclopentenones, leur procede de preparation et leur utilisation |
| CA2285988A1 (en) | 1997-03-17 | 1998-09-24 | Nobuto Koyama | Antiviral agents |
| US6194467B1 (en) | 1997-03-28 | 2001-02-27 | Takara Shuzo Co., Ltd. | Diabetes remedies |
| US6284801B1 (en) | 1997-04-01 | 2001-09-04 | Takara Shuzo Co., Ltd. | Antirheumatic agents |
| EP1008345A4 (de) | 1997-07-02 | 2000-09-13 | Takara Shuzo Co | Antiallergische mittel |
-
1998
- 1998-03-18 US US09/367,163 patent/US6194467B1/en not_active Expired - Fee Related
- 1998-03-18 JP JP54140598A patent/JP3664737B2/ja not_active Expired - Fee Related
- 1998-03-18 KR KR10-1999-7008158A patent/KR100459581B1/ko not_active IP Right Cessation
- 1998-03-18 CA CA002285316A patent/CA2285316A1/en not_active Abandoned
- 1998-03-18 EA EA199900881A patent/EA001763B1/ru not_active IP Right Cessation
- 1998-03-18 WO PCT/JP1998/001151 patent/WO1998043624A1/ja active IP Right Grant
- 1998-03-18 ES ES98909738T patent/ES2227811T3/es not_active Expired - Lifetime
- 1998-03-18 AT AT98909738T patent/ATE274904T1/de not_active IP Right Cessation
- 1998-03-18 EP EP98909738A patent/EP0978278B1/de not_active Expired - Lifetime
- 1998-03-18 DE DE69825981T patent/DE69825981T2/de not_active Expired - Fee Related
- 1998-03-18 CN CN98802986A patent/CN1123339C/zh not_active Expired - Fee Related
- 1998-03-18 AU AU64188/98A patent/AU736516B2/en not_active Ceased
- 1998-03-27 TW TW087104632A patent/TW515714B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| KR20000076070A (ko) | 2000-12-26 |
| WO1998043624A1 (fr) | 1998-10-08 |
| AU736516B2 (en) | 2001-07-26 |
| US6194467B1 (en) | 2001-02-27 |
| ES2227811T3 (es) | 2005-04-01 |
| EP0978278B1 (de) | 2004-09-01 |
| CN1249680A (zh) | 2000-04-05 |
| AU6418898A (en) | 1998-10-22 |
| EP0978278A4 (de) | 2002-08-21 |
| DE69825981T2 (de) | 2005-09-01 |
| EA199900881A1 (ru) | 2000-04-24 |
| JP3664737B2 (ja) | 2005-06-29 |
| KR100459581B1 (ko) | 2004-12-03 |
| EP0978278A1 (de) | 2000-02-09 |
| TW515714B (en) | 2003-01-01 |
| CN1123339C (zh) | 2003-10-08 |
| EA001763B1 (ru) | 2001-08-27 |
| CA2285316A1 (en) | 1998-10-08 |
| DE69825981D1 (de) | 2004-10-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |