ATE150019T1 - Beta-mercapto-propanamidderivate verwendbar zur behandlung kardiovaskularer krankheiten oder erkrankungen - Google Patents

Beta-mercapto-propanamidderivate verwendbar zur behandlung kardiovaskularer krankheiten oder erkrankungen

Info

Publication number
ATE150019T1
ATE150019T1 AT94111584T AT94111584T ATE150019T1 AT E150019 T1 ATE150019 T1 AT E150019T1 AT 94111584 T AT94111584 T AT 94111584T AT 94111584 T AT94111584 T AT 94111584T AT E150019 T1 ATE150019 T1 AT E150019T1
Authority
AT
Austria
Prior art keywords
diseases
treatment
beta
cardiovascular diseases
derivatives usable
Prior art date
Application number
AT94111584T
Other languages
English (en)
Inventor
Gabriele Norcini
Francesco Santangelo
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Spa filed Critical Zambon Spa
Application granted granted Critical
Publication of ATE150019T1 publication Critical patent/ATE150019T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT94111584T 1993-07-30 1994-07-25 Beta-mercapto-propanamidderivate verwendbar zur behandlung kardiovaskularer krankheiten oder erkrankungen ATE150019T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT93MI001723A IT1266571B1 (it) 1993-07-30 1993-07-30 Derivati della beta-mercapto-propanammide utili nel trattamento delle malattie cardiovascolari

Publications (1)

Publication Number Publication Date
ATE150019T1 true ATE150019T1 (de) 1997-03-15

Family

ID=11366739

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94111584T ATE150019T1 (de) 1993-07-30 1994-07-25 Beta-mercapto-propanamidderivate verwendbar zur behandlung kardiovaskularer krankheiten oder erkrankungen

Country Status (5)

Country Link
US (1) US5506259A (de)
EP (1) EP0636621B1 (de)
AT (1) ATE150019T1 (de)
DE (1) DE69402004T2 (de)
IT (1) IT1266571B1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19510566A1 (de) * 1995-03-23 1996-09-26 Kali Chemie Pharma Gmbh Benzazepin-, Benzoxazepin- und Benzothiazepin-N-essigsäurederivate sowie Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
FR2745570B1 (fr) 1996-03-04 1998-06-19 Roussel Uclaf Nouveaux derives soufres comportant une liaison retroamide, leur procede et intermediaires de preparation, leur application a titre de medicaments, et les compositions pharmaceutiques les renfermant
SE9901573D0 (sv) 1999-05-03 1999-05-03 Astra Ab New compounds
US7468390B2 (en) 2002-01-17 2008-12-23 Novartis Ag Methods of treatment and pharmaceutical composition
AR057882A1 (es) 2005-11-09 2007-12-26 Novartis Ag Compuestos de accion doble de bloqueadores del receptor de angiotensina e inhibidores de endopeptidasa neutra
CA2882771C (en) 2012-08-24 2021-02-23 Novartis Ag Nep inhibitors for treating diseases characterized by atrial enlargement or remodeling
WO2017033128A1 (en) 2015-08-25 2017-03-02 Novartis Ag Biphenyl-substitued 4-amino-butyric acid derivatives and their use in the synthesis of nep inhibitors
WO2017072636A1 (en) 2015-10-29 2017-05-04 Cadila Healthcare Limited Pharmaceutical synergistic combination

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1191109B (it) * 1982-12-03 1988-02-24 Simes Derivati di acidi aminopiridincarbossilici,loro metodo di sintesi e composizioni farmaceutiche che li contengono
FR2540495B1 (fr) * 1983-02-07 1986-02-14 Roussel Uclaf Nouveaux derives de o-mercaptopropanamide et de ses homologues, leur procede de preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus
DE3467754D1 (de) * 1983-10-03 1988-01-07 Squibb & Sons Inc Enkephalinase inhibitors
FR2611712B1 (fr) * 1987-02-26 1989-06-23 Roussel Uclaf Nouveaux derives n-substitues de l'alpha-mercaptomethyl benzene propanamide, leur procede de preparation, leur application a titre de medicaments et les compositions les renfermant
EP0318859A3 (de) * 1987-12-03 1990-08-16 Dainippon Pharmaceutical Co., Ltd. N-Substituierte Mercaptopropionamid-Derivate
US4879309A (en) * 1988-09-27 1989-11-07 Schering Corporation Mercapto-acylamino acids as antihypertensives
EP0361365A1 (de) * 1988-09-30 1990-04-04 E.R. SQUIBB & SONS, INC. Derivate von Aminobenzoesäure und Aminocyclohexancarbonsäure, Zusammensetzungen und ihre Verwendung
GB9123353D0 (en) * 1991-11-04 1991-12-18 Fujisawa Pharmaceutical Co New mercapto-amide derivatives,processes for the preparation thereof and pharmaceutical composition comprising the same
GB2272435A (en) * 1992-11-16 1994-05-18 Fujisawa Pharmaceutical Co WS75624 substances from saccharothrix strain

Also Published As

Publication number Publication date
EP0636621A1 (de) 1995-02-01
ITMI931723A0 (it) 1993-07-30
ITMI931723A1 (it) 1995-01-30
US5506259A (en) 1996-04-09
EP0636621B1 (de) 1997-03-12
IT1266571B1 (it) 1997-01-09
DE69402004T2 (de) 1997-06-19
DE69402004D1 (de) 1997-04-17

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties