TR199600970A2 - CDCH'nin yeni kristal modifikasyonu, bunun hazirlanmasi icin bir islem ve bu modifikasyonu iceren farmasotik formülasyonlar. - Google Patents

CDCH'nin yeni kristal modifikasyonu, bunun hazirlanmasi icin bir islem ve bu modifikasyonu iceren farmasotik formülasyonlar.

Info

Publication number
TR199600970A2
TR199600970A2 TR96/00970A TR9600970A TR199600970A2 TR 199600970 A2 TR199600970 A2 TR 199600970A2 TR 96/00970 A TR96/00970 A TR 96/00970A TR 9600970 A TR9600970 A TR 9600970A TR 199600970 A2 TR199600970 A2 TR 199600970A2
Authority
TR
Turkey
Prior art keywords
modification
cdch
preparation
pharmaceutical formulations
formulations containing
Prior art date
Application number
TR96/00970A
Other languages
English (en)
Turkish (tr)
Inventor
Dr Alfons Grunenberg
Dr Patrick Bosche
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7779831&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TR199600970(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of TR199600970A2 publication Critical patent/TR199600970A2/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
TR96/00970A 1995-12-12 1996-12-05 CDCH'nin yeni kristal modifikasyonu, bunun hazirlanmasi icin bir islem ve bu modifikasyonu iceren farmasotik formülasyonlar. TR199600970A2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19546249A DE19546249A1 (de) 1995-12-12 1995-12-12 Neue Kristallmodifikation des 1-Cyclopropyl-7-([S,S]-2,8-diazabicyclo[4,3,0]non-8-yl)-6-fluor-1,4-dihydro-8-methoxy-4-oxo-3-chinolincarbonsäure Hydrochlorid (CDCH), Verfahren zu dessen Herstellung und diese enthaltende pharmazeutische Zubereitungen

Publications (1)

Publication Number Publication Date
TR199600970A2 true TR199600970A2 (tr) 1997-06-21

Family

ID=7779831

Family Applications (1)

Application Number Title Priority Date Filing Date
TR96/00970A TR199600970A2 (tr) 1995-12-12 1996-12-05 CDCH'nin yeni kristal modifikasyonu, bunun hazirlanmasi icin bir islem ve bu modifikasyonu iceren farmasotik formülasyonlar.

Country Status (42)

Country Link
US (1) US5849752A (member.php)
EP (1) EP0780390B1 (member.php)
JP (1) JP4104687B2 (member.php)
KR (1) KR100525146B1 (member.php)
CN (1) CN1061348C (member.php)
AR (1) AR005009A1 (member.php)
AT (1) ATE221531T1 (member.php)
AU (1) AU708006B2 (member.php)
BG (1) BG62258B1 (member.php)
BR (1) BR9605968A (member.php)
CA (1) CA2192418C (member.php)
CO (1) CO4480105A1 (member.php)
CU (1) CU22774A3 (member.php)
CZ (1) CZ288657B6 (member.php)
DE (2) DE19546249A1 (member.php)
DK (1) DK0780390T3 (member.php)
EE (1) EE03474B1 (member.php)
ES (1) ES2179910T3 (member.php)
HR (1) HRP960558B1 (member.php)
HU (1) HU226521B1 (member.php)
ID (1) ID22625A (member.php)
IL (1) IL119795A (member.php)
IN (1) IN185805B (member.php)
MA (1) MA24342A1 (member.php)
MY (1) MY117492A (member.php)
NL (1) NL300109I1 (member.php)
NO (1) NO306725B1 (member.php)
NZ (1) NZ299905A (member.php)
PL (1) PL184885B1 (member.php)
PT (1) PT780390E (member.php)
RO (1) RO119782B1 (member.php)
RU (1) RU2162468C2 (member.php)
SA (1) SA96170492B1 (member.php)
SG (1) SG47201A1 (member.php)
SI (1) SI0780390T1 (member.php)
SK (1) SK282805B6 (member.php)
SV (1) SV1996000109A (member.php)
TR (1) TR199600970A2 (member.php)
TW (1) TW411340B (member.php)
UA (1) UA35638C2 (member.php)
YU (1) YU49485B (member.php)
ZA (1) ZA9610405B (member.php)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ503538A (en) * 1997-09-25 2001-03-30 Bayer Ag Moxifloxacin formulation characterised by the release times containing hydroxypropylmethylcellulose or polyvinylpyrrolidone as binder and ethylcellulose as film forming polymer
DE19751948A1 (de) * 1997-11-24 1999-05-27 Bayer Ag Verfahren zur Herstellung von 8-Methoxy-Chinoloncarbonsäuren
US6716830B2 (en) * 1998-09-30 2004-04-06 Alcon, Inc. Ophthalmic antibiotic compositions containing moxifloxacin
US6395746B1 (en) 1998-09-30 2002-05-28 Alcon Manufacturing, Ltd. Methods of treating ophthalmic, otic and nasal infections and attendant inflammation
US6509327B1 (en) 1998-09-30 2003-01-21 Alcon Manufacturing, Ltd. Compositions and methods for treating otic, ophthalmic and nasal infections
ID29089A (id) * 1998-11-10 2001-07-26 Bayer Ag Sediaan farmasi moksifloksasin
DE19854355A1 (de) * 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation B von 8-Cyan-1-cyclopropyl-7-(1S, 6S-2,8-diazabicyclo-/4.3.O/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19854357A1 (de) * 1998-11-25 2000-05-31 Bayer Ag Semi-Hydrochlorid von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo/4.3.0/ -nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19854356A1 (de) * 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation A von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo-/4.3.0/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19908449A1 (de) * 1999-02-26 2000-08-31 Bayer Ag Kristallmodifikation C von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo-[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino/incarbonsäure
US20060252789A1 (en) * 2002-10-31 2006-11-09 Sujay Biswas Amorphous moxifloxacin hydrochloride
DE602004022646D1 (de) † 2003-04-09 2009-10-01 Reddys Lab Ltd Dr Kristalline form iii von wasserfreiem moxifloxacin-hydrochlorid und ein verfahren zu seiner herstellung
WO2005012285A1 (en) * 2003-08-05 2005-02-10 Matrix Laboratories Ltd An improved process for the preparation of moxifloxacin hydrochloride
ITMI20032259A1 (it) 2003-11-20 2005-05-21 Chemi Spa Nuovo polimorfo dell'acido 1-ciclopropil-7-(s,s-2,8-diazabciclo-4.3.0-non-8-il)-6-fluoro-1,4-diidro-8-metossi-4-oxo-chinolin carbossilico cloridrato e metodi per la sua preparazione
DE602004018370D1 (de) * 2003-11-20 2009-01-22 Chemi Spa Polymorphe von 1-cyclopropyl-7-(äs,sü - 2,8-diazadicyclo ä4.3.0ü non-8-yl) -6-fluor-1,4-dihydro-8-methoxy-4-oxo-3-chinolincarbonsäurehydrochlorid und verfahren zu deren herstellung
US7491725B2 (en) 2004-02-06 2009-02-17 Bristol-Myers Squibb Company Process for preparing 2-aminothiazole-5-aromatic carboxamides as kinase inhibitors
DE102004015981A1 (de) * 2004-04-01 2005-10-20 Bayer Healthcare Ag Neue kirstalline Form von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE102004063347A1 (de) * 2004-12-23 2006-07-13 Stada Arzneimittel Ag Gebrauchsfertige Gemcitabinlösungen und Gemcitabinlösungskonzentrate
WO2007033515A1 (fr) * 2005-09-21 2007-03-29 Shenzhen Tys R & D Co., Ltd. Formulation orale contenant de la moxifloxacine et son procédé de préparation
GB0612422D0 (en) * 2006-06-23 2006-08-02 Generics Uk Ltd Novel hydrate form
DE602007003024D1 (de) 2006-06-27 2009-12-10 Sandoz Ag Neues verfahren zur salzherstellung
ES2303768B1 (es) * 2006-09-08 2009-06-05 Quimica Sintetica, S.A. Nueva forma cristalina de moxifloxacino clorhidrato.
WO2008059223A2 (en) * 2006-11-13 2008-05-22 Cipla Limited Process for the synthesis of moxifloxacin hydrochloride
EP1992626A1 (en) * 2007-05-10 2008-11-19 Sandoz AG Process for the preparation of moxifloxacin hydrochloride
EP2083010A1 (en) * 2008-01-08 2009-07-29 Chemo Ibérica, S.A. Polymorphic Forms of Moxifloxacin hydrochloride and processes for preparation thereof
EP2154137A1 (en) 2008-08-04 2010-02-17 Chemo Ibérica, S.A. Crystalline form of moxifloxacin base
CN102176902B (zh) 2008-10-09 2012-10-31 阿卜迪易卜拉欣贸易公司 有机溶剂在莫西沙星湿法造粒中的应用
WO2010052726A1 (en) * 2008-11-06 2010-05-14 Hetero Research Foundation Novel polymorph of moxifloxacin hydrochloride
US20110293717A1 (en) 2008-12-08 2011-12-01 Ratiopharm Gmbh Compacted moxifloxacin
JP2012526793A (ja) 2009-05-15 2012-11-01 レッドエックス ファーマ リミテッド 酸化還元薬物誘導体
WO2011121596A2 (en) * 2010-04-01 2011-10-06 Neuland Laboratories Ltd. Crystal modification of moxifloxacin hydrochloride
BRPI1106900A2 (pt) 2011-12-26 2013-11-05 Ems Sa Composição farmacêutica sólida compreendendo antibótico da familia das quinolonas e processo de sua obtenção
FR2992218B1 (fr) 2012-06-22 2015-01-23 Rivopharm Sa Composition pharmaceutique de chlorhydrate de moxifloxacine et procede de preparation
CN102924449B (zh) * 2012-10-30 2015-08-12 重庆福安药业集团庆余堂制药有限公司 盐酸莫西沙星h晶型及其制备方法和药物组合物
CA2893534A1 (en) 2012-12-04 2014-06-12 Mankind Research Centre An improved process for the preparation of moxifloxacin hydrochloride
RU2561037C2 (ru) * 2013-02-07 2015-08-20 Открытое акционерное общество "Химико-фармацевтический комбинат "АКРИХИН" (ОАО "АКРИХИН") Антибактериальная фармацевтическая композиция и способ ее получения
CA2904387C (en) 2013-03-15 2021-12-07 Melinta Therapeutics, Inc. Methods of treating infections in overweight and obese patients using antibiotics

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3601567A1 (de) * 1986-01-21 1987-07-23 Bayer Ag 7-(azabicycloalkyl)-chinoloncarbonsaeure- und -naphthyridon-carbonsaeure-derivate
EP0241206A3 (en) * 1986-03-31 1989-05-10 Sankyo Company Limited Quinoline-3-carboxylic acid derivatives, their preparation and use
AU609974B2 (en) * 1988-05-18 1991-05-09 Warner-Lambert Company Improved process for the preparation of 5-amino-7- (substituted amino)-quinoline-3-carboxylic acids
DE3910663A1 (de) * 1989-04-03 1990-10-04 Bayer Ag 5-alkylchinoloncarbonsaeuren
RO108347B1 (ro) * 1989-10-30 1994-04-28 Bellon Labor Sa Roger DERIVATI DE BENZO-(b)-NAFTIRIDIN-1,8 SI PROCEDEU DE PREPARARE A ACESTORA
TW209865B (member.php) 1992-01-10 1993-07-21 Bayer Ag
ATE207479T1 (de) * 1992-01-31 2001-11-15 Chugai Pharmaceutical Co Ltd Kristalle von derivaten von chinozon carbonsäure- hydraten
DE4234078A1 (de) * 1992-10-09 1994-04-14 Bayer Ag Chinoloncarbonsäuren
CA2112165C (en) * 1992-12-25 2003-04-08 Makoto Takemura Bicyclic amine derivatives
ZA946853B (en) * 1993-09-10 1995-04-24 Daiichi Seiyaku Co Crystals of antimicrobial compound.
ATE170400T1 (de) * 1994-04-07 1998-09-15 Pfizer Verwendung von trovafloxacin oder dessen derivaten zur herstellung eines arzneimittels zur behandlung von h.pylori infektionen

Also Published As

Publication number Publication date
PL184885B1 (pl) 2003-01-31
NZ299905A (en) 1998-09-24
TW411340B (en) 2000-11-11
MY117492A (en) 2004-07-31
CO4480105A1 (es) 1997-07-09
AR005009A1 (es) 1999-04-07
BG101043A (en) 1998-04-30
HU9603428D0 (en) 1997-01-28
RO119782B1 (ro) 2005-03-30
KR970042550A (ko) 1997-07-24
CZ364696A3 (en) 1997-07-16
RU2162468C2 (ru) 2001-01-27
JPH09169757A (ja) 1997-06-30
JP4104687B2 (ja) 2008-06-18
CA2192418A1 (en) 1997-06-13
EE9600201A (et) 1997-06-16
DE19546249A1 (de) 1997-06-19
HUP9603428A3 (en) 1997-10-28
YU49485B (sh) 2006-08-17
ATE221531T1 (de) 2002-08-15
CN1061348C (zh) 2001-01-31
AU708006B2 (en) 1999-07-29
KR100525146B1 (ko) 2006-01-27
EP0780390B1 (de) 2002-07-31
ID22625A (id) 1999-12-02
CZ288657B6 (cs) 2001-08-15
HUP9603428A2 (en) 1997-08-28
HRP960558B1 (en) 2002-04-30
MA24342A1 (fr) 1998-07-01
MX9606325A (es) 1997-10-31
CU22774A3 (es) 2002-07-24
HU226521B1 (en) 2009-03-30
PL317415A1 (en) 1997-06-23
CN1160052A (zh) 1997-09-24
SA96170492B1 (ar) 2006-05-23
NO965298D0 (no) 1996-12-11
YU65096A (sh) 1998-12-23
US5849752A (en) 1998-12-15
CA2192418C (en) 2001-06-12
SK282805B6 (sk) 2002-12-03
EP0780390A1 (de) 1997-06-25
IL119795A (en) 1998-12-27
HRP960558A2 (en) 1998-02-28
BR9605968A (pt) 1998-08-18
DK0780390T3 (da) 2002-11-11
NO965298L (no) 1997-06-13
IN185805B (member.php) 2001-05-05
SV1996000109A (es) 1997-10-23
SK159196A3 (en) 1997-10-08
ES2179910T3 (es) 2003-02-01
DE59609501D1 (de) 2002-09-05
SI0780390T1 (en) 2002-10-31
BG62258B1 (bg) 1999-06-30
IL119795A0 (en) 1997-03-18
ZA9610405B (en) 1997-06-23
SG47201A1 (en) 1998-03-20
EE03474B1 (et) 2001-08-15
NL300109I1 (nl) 2003-02-03
UA35638C2 (uk) 2001-04-16
NO306725B1 (no) 1999-12-13
AU7421696A (en) 1997-06-19
PT780390E (pt) 2002-11-29

Similar Documents

Publication Publication Date Title
TR199600970A2 (tr) CDCH'nin yeni kristal modifikasyonu, bunun hazirlanmasi icin bir islem ve bu modifikasyonu iceren farmasotik formülasyonlar.
DK0629608T3 (da) Fremgangsmåde til fremstilling af N-acyl-N,N',N'-ethylendiamintrieddikesyrederivater
DE69003549D1 (de) Silicon enthaltendes kosmetisches praeparat.
DE69009540D1 (de) Arzneimittel enthaltendes Heftpflaster.
MA22668A1 (fr) Procede de preparation d'oxamides .
NO981800D0 (no) FremgangsmÕte for fremstilling av 1,1,1,3,3-pentafluorpentan
TR199600390A2 (tr) Elyaf malzemelerinin boyanmasi ve baskisi icin karbonhidrat bilesiklerinin yardimci madde olarak kullanilmasi.
FI971609L (fi) Menetelmä 4a,5,9,10,11,12-heksahydro-6H-bentsofuro-(3a,3,2-ef)(2)-bentsatsepiinijohdannaisten valmistamiseksi
NO901430D0 (no) Fremgangsmaate til fremstilling av 4(3h)-pteridioner, og medikamenter inneholdende slike.
NO911432L (no) Fremgangsmaate for fremstilling av 3,5-disubstituerte 2-isoksazoliner og isoksazoler.
FI911127A0 (fi) Anordning foer framstaellning av enskilda silikonkristaller.
DK0815092T3 (da) Fremgangsmåde til fremstilling af 1,2-benzisothiazolin-3-oner
HUP9801068A2 (hu) 1,2,3,4-Tetrahidro-2-naftil-amin-származékok, ezek előállítása és alkalmazása, valamint ilyen származékokat tartalmazó gyógyászati készítmények
NO903347D0 (no) Fremgangsmaate for fremstilling av 14,17alfa-ethano- og ethanooestratriener.
EP0423679A3 (en) Process for the preparation of 5-(carbamoyl)-5h-dibenz(b,f)azepines
NO169338C (no) Fremgangsmaate for fremstilling av 5h-dibenz(b,f)azepin-5-karboksamid(karbamazepin)
NO905244D0 (no) Fremgangsmaate for fremstilling av des(64,65)-proinsulin.
NO894516D0 (no) Fremgangsmaate for fremstilling av 1-aminoalkyl-3-oksosubstituert-4-aryl-1,3,4,5-tetrahydro-2h-1,3-benzodiazepin-2-on, og deres anvendelse som medikamenter.
NO885406L (no) Fremgangsmaate for fremstilling av 4-heteroaryl-1,3-benzodiazepiner og 2-substituerte-alfa-(hetero-aryl)benzenetanaminer og anvendelse derav som medikamenter.
NO985550D0 (no) FremgangsmÕte for fremstilling av 2,2'-(1-metyl-1,2-etandiyliden)bis(hydrazinkarboksimidamid)
NO961429D0 (no) Fremgangsmåte for fremstilling av kinolonholdige, orale preparater
HUT51626A (en) Process for producing 5-substituted amino-8-phenyl or substituted phenyl-3h,6h-1,4,5a,8a-tetraaza-ceanaphthylene-3-ones and pharmaceutical preparations containing these compounds
NO985551D0 (no) FremgnagsmÕte for fremstilling av 2,2'-(1-metyl-1,2-etandiyliden)bis(hydrazinkarboksimidamid)
FI940822A0 (fi) Foerfarande foer mikrobiologisk rening av material, som innehaoller skadliga aemnen
NO901892D0 (no) Fremgangsmaate for fremstilling av (2,1-c)(1,3)-benzodiazepiner og deres anvendelse som medikamenter.