EE03474B1 - CDCH kristallimodifikatsioon, selle valmistamismeetod ning seda modifikatsiooni sisaldavad farmatseutilised preparaadid - Google Patents

CDCH kristallimodifikatsioon, selle valmistamismeetod ning seda modifikatsiooni sisaldavad farmatseutilised preparaadid

Info

Publication number
EE03474B1
EE03474B1 EE9600201A EE9600201A EE03474B1 EE 03474 B1 EE03474 B1 EE 03474B1 EE 9600201 A EE9600201 A EE 9600201A EE 9600201 A EE9600201 A EE 9600201A EE 03474 B1 EE03474 B1 EE 03474B1
Authority
EE
Estonia
Prior art keywords
modification
cdch
preparation
pharmaceutical preparations
preparations containing
Prior art date
Application number
EE9600201A
Other languages
English (en)
Estonian (et)
Other versions
EE9600201A (et
Inventor
Grunenberg Alfons
Bosch Patrick
Original Assignee
Bayer Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7779831&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EE03474(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Aktiengesellschaft filed Critical Bayer Aktiengesellschaft
Publication of EE9600201A publication Critical patent/EE9600201A/xx
Publication of EE03474B1 publication Critical patent/EE03474B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
EE9600201A 1995-12-12 1996-12-11 CDCH kristallimodifikatsioon, selle valmistamismeetod ning seda modifikatsiooni sisaldavad farmatseutilised preparaadid EE03474B1 (et)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19546249A DE19546249A1 (de) 1995-12-12 1995-12-12 Neue Kristallmodifikation des 1-Cyclopropyl-7-([S,S]-2,8-diazabicyclo[4,3,0]non-8-yl)-6-fluor-1,4-dihydro-8-methoxy-4-oxo-3-chinolincarbonsäure Hydrochlorid (CDCH), Verfahren zu dessen Herstellung und diese enthaltende pharmazeutische Zubereitungen

Publications (2)

Publication Number Publication Date
EE9600201A EE9600201A (et) 1997-06-16
EE03474B1 true EE03474B1 (et) 2001-08-15

Family

ID=7779831

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9600201A EE03474B1 (et) 1995-12-12 1996-12-11 CDCH kristallimodifikatsioon, selle valmistamismeetod ning seda modifikatsiooni sisaldavad farmatseutilised preparaadid

Country Status (42)

Country Link
US (1) US5849752A (member.php)
EP (1) EP0780390B1 (member.php)
JP (1) JP4104687B2 (member.php)
KR (1) KR100525146B1 (member.php)
CN (1) CN1061348C (member.php)
AR (1) AR005009A1 (member.php)
AT (1) ATE221531T1 (member.php)
AU (1) AU708006B2 (member.php)
BG (1) BG62258B1 (member.php)
BR (1) BR9605968A (member.php)
CA (1) CA2192418C (member.php)
CO (1) CO4480105A1 (member.php)
CU (1) CU22774A3 (member.php)
CZ (1) CZ288657B6 (member.php)
DE (2) DE19546249A1 (member.php)
DK (1) DK0780390T3 (member.php)
EE (1) EE03474B1 (member.php)
ES (1) ES2179910T3 (member.php)
HR (1) HRP960558B1 (member.php)
HU (1) HU226521B1 (member.php)
ID (1) ID22625A (member.php)
IL (1) IL119795A (member.php)
IN (1) IN185805B (member.php)
MA (1) MA24342A1 (member.php)
MY (1) MY117492A (member.php)
NL (1) NL300109I1 (member.php)
NO (1) NO306725B1 (member.php)
NZ (1) NZ299905A (member.php)
PL (1) PL184885B1 (member.php)
PT (1) PT780390E (member.php)
RO (1) RO119782B1 (member.php)
RU (1) RU2162468C2 (member.php)
SA (1) SA96170492B1 (member.php)
SG (1) SG47201A1 (member.php)
SI (1) SI0780390T1 (member.php)
SK (1) SK282805B6 (member.php)
SV (1) SV1996000109A (member.php)
TR (1) TR199600970A2 (member.php)
TW (1) TW411340B (member.php)
UA (1) UA35638C2 (member.php)
YU (1) YU49485B (member.php)
ZA (1) ZA9610405B (member.php)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ503538A (en) * 1997-09-25 2001-03-30 Bayer Ag Moxifloxacin formulation characterised by the release times containing hydroxypropylmethylcellulose or polyvinylpyrrolidone as binder and ethylcellulose as film forming polymer
DE19751948A1 (de) * 1997-11-24 1999-05-27 Bayer Ag Verfahren zur Herstellung von 8-Methoxy-Chinoloncarbonsäuren
US6716830B2 (en) * 1998-09-30 2004-04-06 Alcon, Inc. Ophthalmic antibiotic compositions containing moxifloxacin
US6395746B1 (en) 1998-09-30 2002-05-28 Alcon Manufacturing, Ltd. Methods of treating ophthalmic, otic and nasal infections and attendant inflammation
US6509327B1 (en) 1998-09-30 2003-01-21 Alcon Manufacturing, Ltd. Compositions and methods for treating otic, ophthalmic and nasal infections
ID29089A (id) * 1998-11-10 2001-07-26 Bayer Ag Sediaan farmasi moksifloksasin
DE19854355A1 (de) * 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation B von 8-Cyan-1-cyclopropyl-7-(1S, 6S-2,8-diazabicyclo-/4.3.O/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19854357A1 (de) * 1998-11-25 2000-05-31 Bayer Ag Semi-Hydrochlorid von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo/4.3.0/ -nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19854356A1 (de) * 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation A von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo-/4.3.0/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19908449A1 (de) * 1999-02-26 2000-08-31 Bayer Ag Kristallmodifikation C von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo-[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino/incarbonsäure
US20060252789A1 (en) * 2002-10-31 2006-11-09 Sujay Biswas Amorphous moxifloxacin hydrochloride
DE602004022646D1 (de) † 2003-04-09 2009-10-01 Reddys Lab Ltd Dr Kristalline form iii von wasserfreiem moxifloxacin-hydrochlorid und ein verfahren zu seiner herstellung
WO2005012285A1 (en) * 2003-08-05 2005-02-10 Matrix Laboratories Ltd An improved process for the preparation of moxifloxacin hydrochloride
ITMI20032259A1 (it) 2003-11-20 2005-05-21 Chemi Spa Nuovo polimorfo dell'acido 1-ciclopropil-7-(s,s-2,8-diazabciclo-4.3.0-non-8-il)-6-fluoro-1,4-diidro-8-metossi-4-oxo-chinolin carbossilico cloridrato e metodi per la sua preparazione
DE602004018370D1 (de) * 2003-11-20 2009-01-22 Chemi Spa Polymorphe von 1-cyclopropyl-7-(äs,sü - 2,8-diazadicyclo ä4.3.0ü non-8-yl) -6-fluor-1,4-dihydro-8-methoxy-4-oxo-3-chinolincarbonsäurehydrochlorid und verfahren zu deren herstellung
US7491725B2 (en) 2004-02-06 2009-02-17 Bristol-Myers Squibb Company Process for preparing 2-aminothiazole-5-aromatic carboxamides as kinase inhibitors
DE102004015981A1 (de) * 2004-04-01 2005-10-20 Bayer Healthcare Ag Neue kirstalline Form von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE102004063347A1 (de) * 2004-12-23 2006-07-13 Stada Arzneimittel Ag Gebrauchsfertige Gemcitabinlösungen und Gemcitabinlösungskonzentrate
WO2007033515A1 (fr) * 2005-09-21 2007-03-29 Shenzhen Tys R & D Co., Ltd. Formulation orale contenant de la moxifloxacine et son procédé de préparation
GB0612422D0 (en) * 2006-06-23 2006-08-02 Generics Uk Ltd Novel hydrate form
DE602007003024D1 (de) 2006-06-27 2009-12-10 Sandoz Ag Neues verfahren zur salzherstellung
ES2303768B1 (es) * 2006-09-08 2009-06-05 Quimica Sintetica, S.A. Nueva forma cristalina de moxifloxacino clorhidrato.
WO2008059223A2 (en) * 2006-11-13 2008-05-22 Cipla Limited Process for the synthesis of moxifloxacin hydrochloride
EP1992626A1 (en) * 2007-05-10 2008-11-19 Sandoz AG Process for the preparation of moxifloxacin hydrochloride
EP2083010A1 (en) * 2008-01-08 2009-07-29 Chemo Ibérica, S.A. Polymorphic Forms of Moxifloxacin hydrochloride and processes for preparation thereof
EP2154137A1 (en) 2008-08-04 2010-02-17 Chemo Ibérica, S.A. Crystalline form of moxifloxacin base
CN102176902B (zh) 2008-10-09 2012-10-31 阿卜迪易卜拉欣贸易公司 有机溶剂在莫西沙星湿法造粒中的应用
WO2010052726A1 (en) * 2008-11-06 2010-05-14 Hetero Research Foundation Novel polymorph of moxifloxacin hydrochloride
US20110293717A1 (en) 2008-12-08 2011-12-01 Ratiopharm Gmbh Compacted moxifloxacin
JP2012526793A (ja) 2009-05-15 2012-11-01 レッドエックス ファーマ リミテッド 酸化還元薬物誘導体
WO2011121596A2 (en) * 2010-04-01 2011-10-06 Neuland Laboratories Ltd. Crystal modification of moxifloxacin hydrochloride
BRPI1106900A2 (pt) 2011-12-26 2013-11-05 Ems Sa Composição farmacêutica sólida compreendendo antibótico da familia das quinolonas e processo de sua obtenção
FR2992218B1 (fr) 2012-06-22 2015-01-23 Rivopharm Sa Composition pharmaceutique de chlorhydrate de moxifloxacine et procede de preparation
CN102924449B (zh) * 2012-10-30 2015-08-12 重庆福安药业集团庆余堂制药有限公司 盐酸莫西沙星h晶型及其制备方法和药物组合物
CA2893534A1 (en) 2012-12-04 2014-06-12 Mankind Research Centre An improved process for the preparation of moxifloxacin hydrochloride
RU2561037C2 (ru) * 2013-02-07 2015-08-20 Открытое акционерное общество "Химико-фармацевтический комбинат "АКРИХИН" (ОАО "АКРИХИН") Антибактериальная фармацевтическая композиция и способ ее получения
CA2904387C (en) 2013-03-15 2021-12-07 Melinta Therapeutics, Inc. Methods of treating infections in overweight and obese patients using antibiotics

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3601567A1 (de) * 1986-01-21 1987-07-23 Bayer Ag 7-(azabicycloalkyl)-chinoloncarbonsaeure- und -naphthyridon-carbonsaeure-derivate
EP0241206A3 (en) * 1986-03-31 1989-05-10 Sankyo Company Limited Quinoline-3-carboxylic acid derivatives, their preparation and use
AU609974B2 (en) * 1988-05-18 1991-05-09 Warner-Lambert Company Improved process for the preparation of 5-amino-7- (substituted amino)-quinoline-3-carboxylic acids
DE3910663A1 (de) * 1989-04-03 1990-10-04 Bayer Ag 5-alkylchinoloncarbonsaeuren
RO108347B1 (ro) * 1989-10-30 1994-04-28 Bellon Labor Sa Roger DERIVATI DE BENZO-(b)-NAFTIRIDIN-1,8 SI PROCEDEU DE PREPARARE A ACESTORA
TW209865B (member.php) 1992-01-10 1993-07-21 Bayer Ag
ATE207479T1 (de) * 1992-01-31 2001-11-15 Chugai Pharmaceutical Co Ltd Kristalle von derivaten von chinozon carbonsäure- hydraten
DE4234078A1 (de) * 1992-10-09 1994-04-14 Bayer Ag Chinoloncarbonsäuren
CA2112165C (en) * 1992-12-25 2003-04-08 Makoto Takemura Bicyclic amine derivatives
ZA946853B (en) * 1993-09-10 1995-04-24 Daiichi Seiyaku Co Crystals of antimicrobial compound.
ATE170400T1 (de) * 1994-04-07 1998-09-15 Pfizer Verwendung von trovafloxacin oder dessen derivaten zur herstellung eines arzneimittels zur behandlung von h.pylori infektionen

Also Published As

Publication number Publication date
PL184885B1 (pl) 2003-01-31
NZ299905A (en) 1998-09-24
TW411340B (en) 2000-11-11
MY117492A (en) 2004-07-31
CO4480105A1 (es) 1997-07-09
AR005009A1 (es) 1999-04-07
BG101043A (en) 1998-04-30
HU9603428D0 (en) 1997-01-28
RO119782B1 (ro) 2005-03-30
KR970042550A (ko) 1997-07-24
CZ364696A3 (en) 1997-07-16
RU2162468C2 (ru) 2001-01-27
JPH09169757A (ja) 1997-06-30
JP4104687B2 (ja) 2008-06-18
CA2192418A1 (en) 1997-06-13
EE9600201A (et) 1997-06-16
DE19546249A1 (de) 1997-06-19
HUP9603428A3 (en) 1997-10-28
YU49485B (sh) 2006-08-17
ATE221531T1 (de) 2002-08-15
CN1061348C (zh) 2001-01-31
AU708006B2 (en) 1999-07-29
KR100525146B1 (ko) 2006-01-27
EP0780390B1 (de) 2002-07-31
ID22625A (id) 1999-12-02
CZ288657B6 (cs) 2001-08-15
HUP9603428A2 (en) 1997-08-28
HRP960558B1 (en) 2002-04-30
MA24342A1 (fr) 1998-07-01
MX9606325A (es) 1997-10-31
CU22774A3 (es) 2002-07-24
HU226521B1 (en) 2009-03-30
PL317415A1 (en) 1997-06-23
CN1160052A (zh) 1997-09-24
SA96170492B1 (ar) 2006-05-23
NO965298D0 (no) 1996-12-11
YU65096A (sh) 1998-12-23
US5849752A (en) 1998-12-15
CA2192418C (en) 2001-06-12
SK282805B6 (sk) 2002-12-03
TR199600970A2 (tr) 1997-06-21
EP0780390A1 (de) 1997-06-25
IL119795A (en) 1998-12-27
HRP960558A2 (en) 1998-02-28
BR9605968A (pt) 1998-08-18
DK0780390T3 (da) 2002-11-11
NO965298L (no) 1997-06-13
IN185805B (member.php) 2001-05-05
SV1996000109A (es) 1997-10-23
SK159196A3 (en) 1997-10-08
ES2179910T3 (es) 2003-02-01
DE59609501D1 (de) 2002-09-05
SI0780390T1 (en) 2002-10-31
BG62258B1 (bg) 1999-06-30
IL119795A0 (en) 1997-03-18
ZA9610405B (en) 1997-06-23
SG47201A1 (en) 1998-03-20
NL300109I1 (nl) 2003-02-03
UA35638C2 (uk) 2001-04-16
NO306725B1 (no) 1999-12-13
AU7421696A (en) 1997-06-19
PT780390E (pt) 2002-11-29

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