TNSN06187A1 - Arylpyrazoles substitues servant d'agents parasiticides - Google Patents

Arylpyrazoles substitues servant d'agents parasiticides

Info

Publication number
TNSN06187A1
TNSN06187A1 TNP2006000187A TNSN06187A TNSN06187A1 TN SN06187 A1 TNSN06187 A1 TN SN06187A1 TN P2006000187 A TNP2006000187 A TN P2006000187A TN SN06187 A TNSN06187 A TN SN06187A TN SN06187 A1 TNSN06187 A1 TN SN06187A1
Authority
TN
Tunisia
Prior art keywords
parasiticides
des
leur
cyclopropylpyrazoles
cyclopropyle
Prior art date
Application number
TNP2006000187A
Other languages
English (en)
Inventor
Nathan Anthony Logan Chubb
David Morris Gethin
Kim Thomas Hall
Lee Richard Roberts
Nigel Derek Arthur Walshe
Denis Billen
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of TNSN06187A1 publication Critical patent/TNSN06187A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
    • A01N47/38—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the group >N—CO—N< where at least one nitrogen atom is part of a heterocyclic ring; Thio analogues thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms
    • C07D231/40—Acylated on said nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Abstract

La présente invention concerne une gamme de 1-aryl-4-cyclopropylpyrazoles dans lesquels il existe au moins un atome de fluor fixé au noyau cyclopropyle, des compositions comprenant ces composés, des procédés pour leur synthèse ainsi que leur utilisation comme parasiticides.
TNP2006000187A 2003-12-18 2006-06-16 Arylpyrazoles substitues servant d'agents parasiticides TNSN06187A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0329314.9A GB0329314D0 (en) 2003-12-18 2003-12-18 Substituted arylpyrazoles
PCT/IB2004/004193 WO2005060749A1 (fr) 2003-12-18 2004-12-15 Arylpyrazoles substitues utiles en tant qu'agents parasiticides

Publications (1)

Publication Number Publication Date
TNSN06187A1 true TNSN06187A1 (fr) 2007-11-15

Family

ID=30471290

Family Applications (1)

Application Number Title Priority Date Filing Date
TNP2006000187A TNSN06187A1 (fr) 2003-12-18 2006-06-16 Arylpyrazoles substitues servant d'agents parasiticides

Country Status (33)

Country Link
US (1) US7435753B2 (fr)
EP (1) EP1705989B8 (fr)
JP (2) JP4805164B2 (fr)
KR (1) KR100815637B1 (fr)
CN (1) CN100377645C (fr)
AR (1) AR046942A1 (fr)
AT (1) ATE413809T1 (fr)
AU (1) AU2004304717B2 (fr)
BR (1) BRPI0417810B8 (fr)
CA (1) CA2549479C (fr)
CY (1) CY1108649T1 (fr)
DE (1) DE602004017782D1 (fr)
DK (1) DK1705989T3 (fr)
EA (1) EA010740B1 (fr)
ES (1) ES2315724T3 (fr)
GB (1) GB0329314D0 (fr)
HK (1) HK1096824A1 (fr)
IL (1) IL175992A0 (fr)
IS (1) IS8492A (fr)
MA (1) MA28269A1 (fr)
MX (1) MXPA06007006A (fr)
NO (1) NO20062549L (fr)
NZ (1) NZ547565A (fr)
PL (1) PL1705989T3 (fr)
PT (1) PT1705989E (fr)
RS (1) RS51111B (fr)
SI (1) SI1705989T1 (fr)
TN (1) TNSN06187A1 (fr)
TW (1) TW200526605A (fr)
UA (1) UA83397C2 (fr)
UY (1) UY28670A1 (fr)
WO (1) WO2005060749A1 (fr)
ZA (1) ZA200604715B (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
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US7514464B2 (en) * 2003-12-18 2009-04-07 Pfizer Limited Substituted arylpyrazoles
US20080176865A1 (en) * 2005-06-15 2008-07-24 Pfizer Limited Substituted arylpyrazoles
WO2006134468A1 (fr) * 2005-06-15 2006-12-21 Pfizer Limited Arylpyrazoles substitues pour une utilisation contre les parasites
US20070149464A1 (en) * 2005-06-15 2007-06-28 Pfizer Inc. Combination
US20080146643A1 (en) * 2005-06-15 2008-06-19 Pfizer Limited Combination
US7645786B2 (en) * 2005-06-15 2010-01-12 Pfizer Inc. Substituted arylpyrazoles
KR20080077650A (ko) 2005-12-14 2008-08-25 마켓심 케미칼 웍스 리미티드 5-아미노-1-[2,6-디클로로-4-(트리플루오로메틸)페닐]-4-[(트리플루오로메틸)설피닐]-1ｈ-피라졸-ｓ-카르보니트릴의다형체 및 무정형
FR2928919B1 (fr) * 2008-03-19 2011-07-29 Rhodia Operations Procede de preparation de l'acide difluoroacetique et de ses sels
BRPI0918430A2 (pt) 2008-08-14 2015-11-24 Bayer Cropscience Ag 4-fenil-1h-pirazóis inseticidas.
EP2184273A1 (fr) 2008-11-05 2010-05-12 Bayer CropScience AG Composés substitués par l'halogène comme pesticides
CN102356070B (zh) * 2009-03-16 2014-07-16 巴斯夫欧洲公司 制备吡唑衍生物的方法
EP2253617A1 (fr) 2009-05-20 2010-11-24 Bayer CropScience AG Composés halogénés comme pesticides
US20110129574A1 (en) * 2009-11-30 2011-06-02 Pathak Chandrashekhar P Methods and compositions for filling fleshy fruits and vegetables
CA2794428A1 (fr) 2010-04-08 2011-10-13 Pfizer Inc. Derives de 3,5-diphenyl-isoxazoline substitues comme insecticides et acaricides
JP2012046486A (ja) * 2010-07-30 2012-03-08 Sumitomo Chemical Co Ltd 動物外部寄生虫防除剤
BR112013002871B1 (pt) 2010-08-05 2018-11-21 Zoetis Llc derivados de isoxazolina, seu uso e composição farmacêutica ou veterinária
WO2012038851A1 (fr) 2010-09-24 2012-03-29 Pfizer Inc. Oximes-isoxazolines utilisés en tant qu'agents antiparasites
FR2972452B1 (fr) 2011-03-09 2013-03-15 Rhodia Operations Procede de preparation du difluoroacetonitrile et de ses derives
BR112013023068B8 (pt) 2011-03-10 2022-11-22 Zoetis Llc Derivados de isoxazolina espirocíclica, seu uso e seu processo de preparação, e composições veterinárias
BR112013024074A2 (pt) 2011-03-22 2019-09-24 Zoetis Llc derivado de isoxazolina como agentes antiparasitários
CN104169273B (zh) 2012-02-03 2016-11-02 硕腾服务有限责任公司 作为抗寄生物剂的二氢呋喃氮杂环丁烷衍生物
CN104271568B (zh) 2012-05-09 2016-05-04 硕腾服务有限责任公司 作为抗寄生虫剂的氮杂环丁烷衍生物
US20150297565A1 (en) 2012-12-12 2015-10-22 Zoetis Services Llc Phenylpyrazole injectable compositions

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Also Published As

Publication number Publication date
EP1705989B8 (fr) 2009-03-25
ZA200604715B (en) 2007-03-28
BRPI0417810A (pt) 2007-04-10
CA2549479C (fr) 2009-08-18
IS8492A (is) 2006-05-31
SI1705989T1 (sl) 2009-02-28
CN1893825A (zh) 2007-01-10
MA28269A1 (fr) 2006-11-01
EP1705989A1 (fr) 2006-10-04
US7435753B2 (en) 2008-10-14
UA83397C2 (uk) 2008-07-10
US20050148649A1 (en) 2005-07-07
WO2005060749A1 (fr) 2005-07-07
JP2008174563A (ja) 2008-07-31
AR046942A1 (es) 2006-01-04
JP4805164B2 (ja) 2011-11-02
AU2004304717A1 (en) 2005-07-07
NO20062549L (no) 2006-06-27
EP1705989B1 (fr) 2008-11-12
AU2004304717B2 (en) 2010-11-18
BRPI0417810B8 (pt) 2021-05-25
BRPI0417810B1 (pt) 2018-11-21
CN100377645C (zh) 2008-04-02
NZ547565A (en) 2009-07-31
HK1096824A1 (en) 2007-06-15
TW200526605A (en) 2005-08-16
PL1705989T3 (pl) 2009-04-30
EA010740B1 (ru) 2008-10-30
IL175992A0 (en) 2006-10-05
CY1108649T1 (el) 2014-04-09
KR20060101777A (ko) 2006-09-26
RS51111B (sr) 2010-10-31
PT1705989E (pt) 2009-01-20
ATE413809T1 (de) 2008-11-15
GB0329314D0 (en) 2004-01-21
EA200600979A1 (ru) 2006-10-27
ES2315724T3 (es) 2009-04-01
DK1705989T3 (da) 2009-01-19
CA2549479A1 (fr) 2005-07-07
MXPA06007006A (es) 2006-08-31
DE602004017782D1 (de) 2008-12-24
JP2007514735A (ja) 2007-06-07
KR100815637B1 (ko) 2008-03-20
UY28670A1 (es) 2005-07-29

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