SV1999000060A - Procedimiento para la preparacion de (s,s)-bencil-2,8-diazabiciclo 4.3.0 nonano ref. 32965-sv - Google Patents

Procedimiento para la preparacion de (s,s)-bencil-2,8-diazabiciclo 4.3.0 nonano ref. 32965-sv

Info

Publication number
SV1999000060A
SV1999000060A SV1999000060A SV1999000060A SV1999000060A SV 1999000060 A SV1999000060 A SV 1999000060A SV 1999000060 A SV1999000060 A SV 1999000060A SV 1999000060 A SV1999000060 A SV 1999000060A SV 1999000060 A SV1999000060 A SV 1999000060A
Authority
SV
El Salvador
Prior art keywords
diazabiciclo
bencil
nonano
procedure
preparation
Prior art date
Application number
SV1999000060A
Other languages
English (en)
Spanish (es)
Inventor
Peter Fey
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of SV1999000060A publication Critical patent/SV1999000060A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SV1999000060A 1998-05-11 1999-05-11 Procedimiento para la preparacion de (s,s)-bencil-2,8-diazabiciclo 4.3.0 nonano ref. 32965-sv SV1999000060A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19821039A DE19821039A1 (de) 1998-05-11 1998-05-11 Verfahren zur Herstellung von (S,S)-Benzyl-2,8-diazabicyclo[4.3.0]nonan

Publications (1)

Publication Number Publication Date
SV1999000060A true SV1999000060A (es) 1999-10-27

Family

ID=7867389

Family Applications (1)

Application Number Title Priority Date Filing Date
SV1999000060A SV1999000060A (es) 1998-05-11 1999-05-11 Procedimiento para la preparacion de (s,s)-bencil-2,8-diazabiciclo 4.3.0 nonano ref. 32965-sv

Country Status (13)

Country Link
US (1) US6235908B1 (https=)
EP (1) EP1077979B1 (https=)
JP (1) JP4554076B2 (https=)
AR (1) AR019123A1 (https=)
AU (1) AU3824599A (https=)
CA (1) CA2331526C (https=)
CO (1) CO4830459A1 (https=)
DE (2) DE19821039A1 (https=)
ES (1) ES2245101T3 (https=)
PE (1) PE20000477A1 (https=)
SV (1) SV1999000060A (https=)
UY (1) UY25501A1 (https=)
WO (1) WO1999058532A1 (https=)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE285821T1 (de) * 1999-10-08 2005-01-15 Affinium Pharm Inc Fab i inhibitoren
US6476046B1 (en) 2000-12-04 2002-11-05 Sepracor, Inc. Diazabicyclo[4.3.0]nonanes, and methods of use thereof
CA2444597A1 (en) * 2001-04-06 2002-10-06 Affinium Pharmaceuticals, Inc. Fab i inhibitors
EP1575951B1 (en) 2002-12-06 2014-06-25 Debiopharm International SA Heterocyclic compounds, methods of making them and their use in therapy
DE602004016831D1 (de) 2003-03-17 2008-11-13 Affinium Pharm Inc Pharmazeutische zusammensetzungen inhibitoren von fab i und weitere antibiotika enthaltend
EP2848614A3 (en) 2004-06-04 2015-07-29 Debiopharm International SA Acrylamide derivatives as antibiotic agents
EP1973902A2 (en) * 2005-12-05 2008-10-01 Affinium Pharmaceuticals, Inc. 3-heterocyclylacrylamide compounds as fabi inhibitors and antibacterial agents
EP2687533B1 (en) 2006-07-20 2017-07-19 Debiopharm International SA Acrylamide derivatives as FAB I inhibitors
JP2010509305A (ja) * 2006-11-13 2010-03-25 シプラ・リミテッド モキシフロキサシン塩酸塩の合成方法
US7692015B2 (en) * 2007-01-05 2010-04-06 Zheqing Wang Economical process for preparing (S, S)-2, 8-diazabicyclo[4.3.0]nonane and its enantiomer
WO2008098374A1 (en) 2007-02-16 2008-08-21 Affinium Pharmaceuticals, Inc. Salts, prodrugs and polymorphs of fab i inhibitors
WO2009125425A2 (en) * 2008-02-08 2009-10-15 Neuland Laboratories Ltd Improved process for the preparation of (s.s)-2.8-diazabicyclo[4.3.0]nonane
IT1393337B1 (it) 2009-03-06 2012-04-20 Italiana Sint Spa Sintesi di (4as, 7as)-ottaidro-1h-pirrolo[3,4-b]piridina
CN103044418B (zh) * 2011-10-14 2015-02-04 上海朴颐化学科技有限公司 (s,s)-2,8-二氮杂双环[4,3,0]壬烷的不对称合成方法、相关原料及制备方法
SI2861608T1 (sl) 2012-06-19 2019-08-30 Debiopharm International Sa Derivati predzdravila (E)-N-metil-N-((3-metilbenzofuran-2-IL)metil)- 3-(7-okso-5,6,7,8-tetrahidro-1 ,8-nafthiridin-3-il)akrilamid
BR122023021456A2 (pt) 2016-02-26 2024-02-20 Debiopharm International S.A. Uso de di-hidrogeno fosfato de {6- [(e)-3-{metil[(3-metil-1-benfofuran-2- iol)metil]amino)-3- oxopro-1-en-1-il]-2-oxo-3,4-di-hidro-1,8-naftiridin-1(2h)- il}metila para tratamento de osteomielite do pé diabético e composição farmacêutica
LT3923914T (lt) 2019-02-14 2023-07-25 Debiopharm International S.A. Afabicino kompozicija, jos gamybos būdas
CN113939306B (zh) 2019-06-14 2024-07-19 德彪药业国际股份公司 用于治疗涉及生物膜的细菌感染的药物及其用途
CN112574197B (zh) * 2020-12-07 2021-12-31 泰安汉威集团有限公司 一种化合物c的手性纯化方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB354975A (en) * 1929-07-19 1931-08-20 Ig Farbenindustrie Ag Manufacture of optically active phenylpropanol-methylamines
HU194221B (en) * 1985-04-19 1988-01-28 Richter Gedeon Vegyeszet Process for preparing novel octahydro-indolo/2,3-a/quinoline derivative and pharmaceutical comprising this compound
JPH0285235A (ja) * 1988-09-22 1990-03-26 Kohjin Co Ltd 光学活性アミノアルコール類の製法
JP2995704B2 (ja) * 1989-02-17 1999-12-27 東京化成工業株式会社 光学活性な１ｈ−３−アミノピロリジン化合物の製造法
IT1231158B (it) * 1989-07-20 1991-11-19 Dompe Farmaceutici Spa Procedimento per la risoluzione ottica della dropropizina.
DK0569387T3 (da) * 1991-01-31 1995-07-03 Pfizer Optisk adskillelse af trans-2-(2-pyrimidinyl)-7-(hydroxymethyl)octahydro-2H-pyrido/1,2-a/ pyrazin
TW209865B (https=) * 1992-01-10 1993-07-21 Bayer Ag
DE4234078A1 (de) * 1992-10-09 1994-04-14 Bayer Ag Chinoloncarbonsäuren
DE4234330A1 (de) * 1992-10-12 1994-04-14 Bayer Ag Chinoloncarbonsäuren
NO301165B1 (no) * 1992-12-25 1997-09-22 Daiichi Seiyaku Co Bicykliske aminderivater og antibakterielle midler inneholdende disse
US5686614A (en) * 1995-04-11 1997-11-11 Neurogen Corporation Preparation of chiral 5-aminocarbonyl-5H-dibenzo a,d!cyclohepten-5,10-imines by optical resolution
DE19601745C1 (de) 1996-01-19 1997-10-09 Gruenenthal Gmbh Verfahren zur Racematspaltung von Tramadol

Also Published As

Publication number Publication date
US6235908B1 (en) 2001-05-22
WO1999058532A1 (de) 1999-11-18
EP1077979B1 (de) 2005-07-06
JP4554076B2 (ja) 2010-09-29
AU3824599A (en) 1999-11-29
PE20000477A1 (es) 2000-07-07
ES2245101T3 (es) 2005-12-16
UY25501A1 (es) 1999-11-17
CA2331526A1 (en) 1999-11-18
CO4830459A1 (es) 1999-08-30
DE19821039A1 (de) 1999-11-18
JP2002514648A (ja) 2002-05-21
DE59912242D1 (de) 2005-08-11
EP1077979A1 (de) 2001-02-28
AR019123A1 (es) 2001-12-26
CA2331526C (en) 2011-09-13

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