SU426365A3 - Способ получения производнб1х1-арил-2,3,4,5-тетрагидро-1н-1,5-бензодиазепин-2-она - Google Patents
Способ получения производнб1х1-арил-2,3,4,5-тетрагидро-1н-1,5-бензодиазепин-2-онаInfo
- Publication number
- SU426365A3 SU426365A3 SU1707513A SU1707513A SU426365A3 SU 426365 A3 SU426365 A3 SU 426365A3 SU 1707513 A SU1707513 A SU 1707513A SU 1707513 A SU1707513 A SU 1707513A SU 426365 A3 SU426365 A3 SU 426365A3
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- tetrahydro
- aryl
- benzodiazepin
- obtaining
- binh1x1
- Prior art date
Links
- 238000000034 method Methods 0.000 title description 7
- 125000004432 carbon atom Chemical group C* 0.000 description 9
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 4
- 239000002253 acid Substances 0.000 description 4
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 3
- 125000004182 2-chlorophenyl group Chemical group [H]C1=C([H])C(Cl)=C(*)C([H])=C1[H] 0.000 description 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 2
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 2
- 125000004457 alkyl amino carbonyl group Chemical group 0.000 description 2
- 125000003282 alkyl amino group Chemical group 0.000 description 2
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 239000000460 chlorine Substances 0.000 description 2
- 229910052801 chlorine Inorganic materials 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 125000004663 dialkyl amino group Chemical group 0.000 description 2
- -1 ethoxy, amino Chemical group 0.000 description 2
- 229910052739 hydrogen Inorganic materials 0.000 description 2
- 239000001257 hydrogen Substances 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Natural products CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 1
- 238000005917 acylation reaction Methods 0.000 description 1
- 125000003545 alkoxy group Chemical group 0.000 description 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 description 1
- 125000004429 atom Chemical group 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 description 1
- 150000001805 chlorine compounds Chemical class 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 125000004473 dialkylaminocarbonyl group Chemical group 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 125000001301 ethoxy group Chemical group [H]C([H])([H])C([H])([H])O* 0.000 description 1
- RIFGWPKJUGCATF-UHFFFAOYSA-N ethyl chloroformate Chemical compound CCOC(Cl)=O RIFGWPKJUGCATF-UHFFFAOYSA-N 0.000 description 1
- 125000004494 ethyl ester group Chemical group 0.000 description 1
- 150000004820 halides Chemical class 0.000 description 1
- 239000005457 ice water Substances 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/12—1,5-Benzodiazepines; Hydrogenated 1,5-benzodiazepines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2052840A DE2052840C2 (de) | 1970-10-28 | 1970-10-28 | 8-Chlor-1-phenyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-on-Derivate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU426365A3 true SU426365A3 (ru) | 1974-04-30 |
Family
ID=5786353
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU1707513A SU426365A3 (ru) | 1970-10-28 | 1971-10-20 | Способ получения производнб1х1-арил-2,3,4,5-тетрагидро-1н-1,5-бензодиазепин-2-она |
| SU1707512A SU426366A3 (ru) | 1970-10-28 | 1971-10-20 | Способ получения производных1-арил-2,3,4,5 тетрагидро-1 н-1,5-бензодиазепин-2-она |
| SU1951121A SU474986A3 (ru) | 1970-10-28 | 1971-10-20 | Способ получени производных 1-арил2,3,4,5-тетрагидро-1н-1,5 бензодиазепин-2-она |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU1707512A SU426366A3 (ru) | 1970-10-28 | 1971-10-20 | Способ получения производных1-арил-2,3,4,5 тетрагидро-1 н-1,5-бензодиазепин-2-она |
| SU1951121A SU474986A3 (ru) | 1970-10-28 | 1971-10-20 | Способ получени производных 1-арил2,3,4,5-тетрагидро-1н-1,5 бензодиазепин-2-она |
Country Status (14)
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5960118U (ja) * | 1982-10-18 | 1984-04-19 | 大日本印刷株式会社 | 六角手提箱 |
| JPS59106316U (ja) * | 1982-12-29 | 1984-07-17 | レンゴ−株式会社 | ケ−ス |
| JPS6038260U (ja) * | 1983-08-22 | 1985-03-16 | 凸版印刷株式会社 | バツグ・イン・ボツクス |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1670190A1 (de) * | 1967-02-07 | 1970-12-03 | Boehringer Sohn Ingelheim | Verfahren zur Herstellung von 1,5-Dihydro-5-phenyl-3H-1,5-benzodiazepin-2,4-dionen |
| AT283372B (de) * | 1968-04-29 | 1970-08-10 | Boehringer Sohn Ingelheim | Verfahren zur Herstellung neuer 1-Acyl-5-phenyl-1H-1,5-benzodiazepin-2,4-[3H,5H]-dione |
| DE1934607A1 (de) * | 1968-07-12 | 1970-01-22 | Boehringer Sohn Ingelheim | Verfahren zur Herstellung neuer 5-Aryl-1H-1,5-benzodiazepin-2,4-dione |
| DE1933666A1 (de) * | 1968-08-17 | 1970-09-03 | Egyt Gyogyszervegyeszeti Gyar | Neue 2,3-Dihydro-6,7-benzo-(1,5)-diazepine und Verfahren zur Herstellung derselben |
-
1970
- 1970-10-28 DE DE2052840A patent/DE2052840C2/de not_active Expired
-
1971
- 1971-09-23 ZA ZA726397A patent/ZA726397B/xx unknown
- 1971-10-20 SU SU1707513A patent/SU426365A3/ru active
- 1971-10-20 SU SU1707512A patent/SU426366A3/ru active
- 1971-10-20 SU SU1951121A patent/SU474986A3/ru active
- 1971-10-22 CS CS7440A patent/CS161142B2/cs unknown
- 1971-10-22 ES ES396300A patent/ES396300A1/es not_active Expired
- 1971-10-22 CS CS7898A patent/CS161143B2/cs unknown
- 1971-10-22 CS CS7439A patent/CS161141B2/cs unknown
- 1971-10-22 CS CS7437A patent/CS161140B2/cs unknown
- 1971-10-23 ES ES396302A patent/ES396302A1/es not_active Expired
- 1971-10-25 YU YU2701/71A patent/YU34479B/xx unknown
- 1971-10-25 YU YU2700/71A patent/YU36765B/xx unknown
- 1971-10-25 YU YU2699/71A patent/YU35003B/xx unknown
- 1971-10-25 ES ES396365A patent/ES396365A1/es not_active Expired
- 1971-10-27 CA CA126274A patent/CA918660A/en not_active Expired
- 1971-10-27 CH CH1566171A patent/CH557357A/xx not_active IP Right Cessation
- 1971-10-27 CH CH1566271A patent/CH565773A5/xx not_active IP Right Cessation
- 1971-10-27 CH CH1566371A patent/CH555834A/xx not_active IP Right Cessation
- 1971-10-27 SE SE7113642A patent/SE389109B/xx unknown
- 1971-10-27 DK DK522871A patent/DK138016C/da not_active IP Right Cessation
- 1971-10-27 AT AT926071A patent/AT309441B/de not_active IP Right Cessation
- 1971-10-27 JP JP8546071A patent/JPS5626664B1/ja active Pending
- 1971-10-27 NL NL7114818A patent/NL7114818A/xx not_active Application Discontinuation
- 1971-10-27 AT AT925971A patent/AT309440B/de not_active IP Right Cessation
- 1971-10-27 AT AT926171A patent/AT309442B/de not_active IP Right Cessation
- 1971-10-27 JP JP8546171A patent/JPS5535385B1/ja active Pending
- 1971-10-27 SE SE7113643A patent/SE389110B/xx unknown
- 1971-10-27 NL NLAANVRAGE7114817,A patent/NL171983C/xx not_active IP Right Cessation
- 1971-10-27 NL NL7114816A patent/NL7114816A/xx not_active Application Discontinuation
- 1971-10-28 HU HUKO2464A patent/HU162820B/hu unknown
- 1971-10-28 HU HUKO2465A patent/HU163297B/hu unknown
- 1971-10-28 HU HUKO2466A patent/HU162821B/hu unknown
-
1981
- 1981-04-27 YU YU1088/81A patent/YU37128B/xx unknown
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