SU1327790A3 - Способ получени человеческого инсулина или его аналогов - Google Patents

Способ получени человеческого инсулина или его аналогов Download PDF

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Publication number
SU1327790A3
SU1327790A3 SU813269596A SU3269596A SU1327790A3 SU 1327790 A3 SU1327790 A3 SU 1327790A3 SU 813269596 A SU813269596 A SU 813269596A SU 3269596 A SU3269596 A SU 3269596A SU 1327790 A3 SU1327790 A3 SU 1327790A3
Authority
SU
USSR - Soviet Union
Prior art keywords
insulin
solution
chain
reaction
dtt
Prior art date
Application number
SU813269596A
Other languages
English (en)
Russian (ru)
Inventor
Юджин Чанс Рональд
Артур Хоффманн Джеймс
Original Assignee
Эли Лилли Энд Компани (Фирма)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Эли Лилли Энд Компани (Фирма) filed Critical Эли Лилли Энд Компани (Фирма)
Application granted granted Critical
Publication of SU1327790A3 publication Critical patent/SU1327790A3/ru

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C07K1/067—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for sulfur-containing functions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SU813269596A 1980-03-27 1981-03-26 Способ получени человеческого инсулина или его аналогов SU1327790A3 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13439080A 1980-03-27 1980-03-27

Publications (1)

Publication Number Publication Date
SU1327790A3 true SU1327790A3 (ru) 1987-07-30

Family

ID=22463156

Family Applications (1)

Application Number Title Priority Date Filing Date
SU813269596A SU1327790A3 (ru) 1980-03-27 1981-03-26 Способ получени человеческого инсулина или его аналогов

Country Status (28)

Country Link
EP (1) EP0037256B1 (enExample)
JP (1) JPS56154443A (enExample)
KR (1) KR840000947B1 (enExample)
AR (1) AR227305A1 (enExample)
AT (1) ATE4638T1 (enExample)
AU (1) AU540645B2 (enExample)
CA (1) CA1155109A (enExample)
CS (1) CS236463B2 (enExample)
DD (1) DD157613A5 (enExample)
DE (1) DE3160862D1 (enExample)
DK (1) DK149756C (enExample)
EG (1) EG15248A (enExample)
ES (1) ES500750A0 (enExample)
FI (1) FI810918L (enExample)
GB (1) GB2072680B (enExample)
GR (1) GR73619B (enExample)
HU (1) HU185416B (enExample)
IE (1) IE51608B1 (enExample)
IL (1) IL62483A (enExample)
NO (1) NO151897C (enExample)
NZ (1) NZ196610A (enExample)
PH (1) PH16153A (enExample)
PL (1) PL128599B1 (enExample)
PT (1) PT72733B (enExample)
RO (1) RO81640B (enExample)
SU (1) SU1327790A3 (enExample)
YU (1) YU76981A (enExample)
ZA (1) ZA811970B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4451396A (en) * 1983-08-01 1984-05-29 Eli Lilly And Company Process for inhibiting undesired thiol reactions during cyanogen bromide cleavage of peptides
DE3501641A1 (de) * 1985-01-19 1986-07-24 Hoechst Ag, 6230 Frankfurt Verfahren zur gewinnung von insulin-vorlaeufern aus reaktionsgemischen, die bei der faltung von insulin-vorlaeufern aus den entsprechenden s-sulfonaten anfallen
US4835251A (en) * 1986-06-23 1989-05-30 Genetech, Inc. Method of chain combination
GB8927546D0 (en) * 1989-12-06 1990-02-07 Ciba Geigy Process for the production of biologically active tgf-beta
JP3406244B2 (ja) 1999-04-30 2003-05-12 伊藤ハム株式会社 新規な融合蛋白質からの組み換えインスリンの製造方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Dixon G.H., Wardlaw А.С. Rege- nesation of insulin activity from the separated and inactive A and В Chains. - Nature, 1960, 188, 721-724. *

Also Published As

Publication number Publication date
NO151897B (no) 1985-03-18
DD157613A5 (de) 1982-11-24
CA1155109A (en) 1983-10-11
DK149756C (da) 1987-06-15
PT72733B (en) 1982-03-22
ES8207551A1 (es) 1982-09-16
IL62483A (en) 1984-05-31
HU185416B (en) 1985-02-28
EP0037256A1 (en) 1981-10-07
GB2072680A (en) 1981-10-07
JPS6318960B2 (enExample) 1988-04-20
DK149756B (da) 1986-09-22
AU6884481A (en) 1981-10-01
IE51608B1 (en) 1987-01-21
YU76981A (en) 1983-09-30
EP0037256B1 (en) 1983-09-14
DK136581A (da) 1981-09-28
GR73619B (enExample) 1984-03-26
RO81640A (ro) 1983-04-29
EG15248A (en) 1985-12-31
ZA811970B (en) 1982-11-24
PT72733A (en) 1981-04-01
KR840000947B1 (ko) 1984-07-01
FI810918A7 (fi) 1981-09-28
NO811038L (no) 1981-09-28
PH16153A (en) 1983-07-12
AU540645B2 (en) 1984-11-29
IE810680L (en) 1981-09-27
AR227305A1 (es) 1982-10-15
ES500750A0 (es) 1982-09-16
NO151897C (no) 1985-06-26
FI810918L (fi) 1981-09-28
CS236463B2 (en) 1985-05-15
JPS56154443A (en) 1981-11-30
PL128599B1 (en) 1984-02-29
KR830004855A (ko) 1983-07-20
DE3160862D1 (en) 1983-10-20
IL62483A0 (en) 1981-05-20
NZ196610A (en) 1984-03-16
GB2072680B (en) 1983-09-21
ATE4638T1 (de) 1983-09-15
PL230295A1 (enExample) 1981-11-13
RO81640B (ro) 1983-04-30

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SU1327790A3 (ru) Способ получени человеческого инсулина или его аналогов
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