SMT201700006B - Analoghi della triazina e uso di essi come agenti terapeutici e sonde diagnostiche - Google Patents
Analoghi della triazina e uso di essi come agenti terapeutici e sonde diagnosticheInfo
- Publication number
- SMT201700006B SMT201700006B SM201700006T SM201700006T SMT201700006B SM T201700006 B SMT201700006 B SM T201700006B SM 201700006 T SM201700006 T SM 201700006T SM 201700006 T SM201700006 T SM 201700006T SM T201700006 B SMT201700006 B SM T201700006B
- Authority
- SM
- San Marino
- Prior art keywords
- analogues
- triazine
- therapeutic agents
- diagnostic probes
- probes
- Prior art date
Links
- JYEUMXHLPRZUAT-UHFFFAOYSA-N 1,2,3-triazine Chemical compound C1=CN=NN=C1 JYEUMXHLPRZUAT-UHFFFAOYSA-N 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 239000000523 sample Substances 0.000 title 1
- 229940124597 therapeutic agent Drugs 0.000 title 1
Classifications
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- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
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- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
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- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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PCT/IB2009/007404 WO2010052569A2 (en) | 2008-11-10 | 2009-11-10 | Triazine, pyrimidine and pyridine analogs and their use as therapeutic agents and diagnostic probes |
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EP2402347A1 (en) * | 2006-04-26 | 2012-01-04 | F. Hoffmann-La Roche AG | Pharmaceutical compounds |
NZ575274A (en) | 2006-08-08 | 2010-11-26 | Chugai Pharmaceutical Co Ltd | Pyrimidine derivative as pi3k inhibitor and use thereof |
WO2008032033A1 (en) * | 2006-09-14 | 2008-03-20 | Astrazeneca Ab | 4-benzimidazolyl-2-morpholino-6-piperazinylpyrimidine derivatives as pi3k and mtor inhibitors for the treatment of proliferative disorders |
WO2008072850A1 (en) * | 2006-12-11 | 2008-06-19 | Amorepacific Corporation | Triazine derivatives having inhibitory activity against acetyl-coa carboxylase |
CN101711241A (zh) * | 2007-02-06 | 2010-05-19 | 诺瓦提斯公司 | Pi3-激酶抑制剂和它们的使用方法 |
WO2009093981A1 (en) * | 2008-01-23 | 2009-07-30 | S Bio Pte Ltd | Triazine compounds as kinase inhibitors |
EP2082777A1 (en) * | 2008-01-27 | 2009-07-29 | Oncotherm Kft. | Flexible and porous large-area electrode for heating |
DE202008001253U1 (de) * | 2008-01-28 | 2008-04-10 | Mirror Image Ag | Bildanzeigegerät |
CA2721710A1 (en) | 2008-05-23 | 2009-11-26 | Wyeth Llc | Triazine compounds as pi3 kinase and mtor inhibitors |
GB2465405A (en) * | 2008-11-10 | 2010-05-19 | Univ Basel | Triazine, pyrimidine and pyridine analogues and their use in therapy |
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2008
- 2008-11-10 GB GB0821219A patent/GB2465405A/en not_active Withdrawn
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2009
- 2009-11-10 US US13/128,436 patent/US8921361B2/en active Active
- 2009-11-10 CN CN200980144674.6A patent/CN102209714B/zh active Active
- 2009-11-10 NZ NZ592617A patent/NZ592617A/en active IP Right Revival
- 2009-11-10 BR BRPI0921709-6A patent/BRPI0921709B1/pt active IP Right Grant
- 2009-11-10 MX MX2011004889A patent/MX2011004889A/es active IP Right Grant
- 2009-11-10 CA CA2741990A patent/CA2741990C/en active Active
- 2009-11-10 RU RU2011114559/04A patent/RU2537945C2/ru active
- 2009-11-10 KR KR1020117013081A patent/KR101749192B1/ko active IP Right Grant
- 2009-11-10 JP JP2011535182A patent/JP5738768B2/ja active Active
- 2009-11-10 EP EP09764032.0A patent/EP2364302B1/en active Active
- 2009-11-10 DK DK09764032.0T patent/DK2364302T3/en active
- 2009-11-10 WO PCT/IB2009/007404 patent/WO2010052569A2/en active Application Filing
- 2009-11-10 SI SI200931578A patent/SI2364302T1/sl unknown
- 2009-11-10 ES ES09764032.0T patent/ES2609296T3/es active Active
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