SMT201600253B - Terapia di combinazione per il trattamento del cancro della mammella - Google Patents

Terapia di combinazione per il trattamento del cancro della mammella

Info

Publication number
SMT201600253B
SMT201600253B SM201600253T SM201600253T SMT201600253B SM T201600253 B SMT201600253 B SM T201600253B SM 201600253 T SM201600253 T SM 201600253T SM 201600253 T SM201600253 T SM 201600253T SM T201600253 B SMT201600253 B SM T201600253B
Authority
SM
San Marino
Prior art keywords
breast cancer
combination therapy
cancer treatment
treatment
therapy
Prior art date
Application number
SM201600253T
Other languages
English (en)
Inventor
Jay Harper
Scott Michael Lonning
Frank James Hsu
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of SMT201600253B publication Critical patent/SMT201600253B/it

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/427Thiazoles not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1841Transforming growth factor [TGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SM201600253T 2010-03-12 2016-07-27 Terapia di combinazione per il trattamento del cancro della mammella SMT201600253B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31351510P 2010-03-12 2010-03-12
EP11753944.5A EP2544541B1 (en) 2010-03-12 2011-03-08 Combination therapy for treating breast cancer

Publications (1)

Publication Number Publication Date
SMT201600253B true SMT201600253B (it) 2016-08-31

Family

ID=44563812

Family Applications (1)

Application Number Title Priority Date Filing Date
SM201600253T SMT201600253B (it) 2010-03-12 2016-07-27 Terapia di combinazione per il trattamento del cancro della mammella

Country Status (17)

Country Link
US (3) US8911736B2 (it)
EP (4) EP2544541B1 (it)
JP (2) JP5917418B2 (it)
CY (1) CY1117831T1 (it)
DK (2) DK2835053T3 (it)
ES (2) ES2694288T3 (it)
HR (2) HRP20160932T1 (it)
HU (2) HUE040107T2 (it)
LT (1) LT3117709T (it)
ME (1) ME02464B (it)
PL (2) PL3117709T3 (it)
PT (2) PT3117709T (it)
RS (2) RS57942B1 (it)
SI (2) SI2835053T1 (it)
SM (1) SMT201600253B (it)
TR (1) TR201816180T4 (it)
WO (1) WO2011112609A1 (it)

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US8911736B2 (en) * 2010-03-12 2014-12-16 Genzyme Corporation Combination therapy for treating breast cancer
WO2013078286A1 (en) * 2011-11-22 2013-05-30 Cornell University Methods for stimulating hematopoietic recovery by inhibiting tgf beta signaling
BR112015021595A2 (pt) 2013-03-11 2017-10-10 Genzyme Corp anticorpos anti-tgf-beta engenheirados e fragmentos de ligação do antígeno
WO2016094697A2 (en) * 2014-12-10 2016-06-16 The Regents Of The University Of Colorado, A Body Corporate Targeting breast cancer therapy based on stromal subtypes and cd146 composition
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CN107427363B (zh) * 2015-03-18 2020-08-28 Med-El电气医疗器械有限公司 骨传导漂浮质量传感器的固定
KR102647231B1 (ko) 2018-08-02 2024-03-13 삼성전자주식회사 반도체 소자 및 이의 제조방법

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Also Published As

Publication number Publication date
PT3117709T (pt) 2018-11-15
EP2544541A4 (en) 2013-07-31
HUE027831T2 (en) 2016-11-28
JP6289528B2 (ja) 2018-03-07
TR201816180T4 (tr) 2018-11-21
HUE040107T2 (hu) 2019-02-28
PL3117709T3 (pl) 2019-01-31
ME02464B (me) 2017-02-20
US9539325B2 (en) 2017-01-10
HRP20181757T1 (hr) 2019-01-25
EP2835053B1 (en) 2016-04-27
WO2011112609A1 (en) 2011-09-15
DK3117709T3 (en) 2018-11-26
LT3117709T (lt) 2018-11-26
US10507242B2 (en) 2019-12-17
EP2544541A1 (en) 2013-01-16
US20130034549A1 (en) 2013-02-07
PL2835053T3 (pl) 2016-12-30
RS57942B1 (sr) 2019-01-31
US20150086547A1 (en) 2015-03-26
ES2694288T3 (es) 2018-12-19
ES2584433T3 (es) 2016-09-27
EP3117709A1 (en) 2017-01-18
HK1206936A1 (en) 2016-01-22
JP5917418B2 (ja) 2016-05-11
CY1117831T1 (el) 2017-05-17
JP2013522210A (ja) 2013-06-13
HRP20160932T1 (hr) 2016-10-07
US20170319691A1 (en) 2017-11-09
SI2835053T1 (sl) 2016-09-30
EP2544541B1 (en) 2014-10-08
JP2016164174A (ja) 2016-09-08
EP2835053A1 (en) 2015-02-11
PT2835053T (pt) 2016-07-14
EP3117709B1 (en) 2018-08-01
EP3406141B1 (en) 2020-10-14
SI3117709T1 (sl) 2018-12-31
RS54972B1 (sr) 2016-11-30
EP3406141A1 (en) 2018-11-28
US8911736B2 (en) 2014-12-16
DK2835053T3 (en) 2016-08-15

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