HRP20181757T1 - Kombinirana terapija za liječenje raka dojke - Google Patents

Kombinirana terapija za liječenje raka dojke

Info

Publication number
HRP20181757T1
HRP20181757T1 HRP20181757TT HRP20181757T HRP20181757T1 HR P20181757 T1 HRP20181757 T1 HR P20181757T1 HR P20181757T T HRP20181757T T HR P20181757TT HR P20181757 T HRP20181757 T HR P20181757T HR P20181757 T1 HRP20181757 T1 HR P20181757T1
Authority
HR
Croatia
Prior art keywords
breast cancer
combination therapy
treating breast
treating
therapy
Prior art date
Application number
HRP20181757TT
Other languages
English (en)
Inventor
Jay Harper
Scott Michael Lonning
Frank James Hsu
Original Assignee
Genzyme Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corporation filed Critical Genzyme Corporation
Publication of HRP20181757T1 publication Critical patent/HRP20181757T1/hr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/427Thiazoles not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1841Transforming growth factor [TGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
HRP20181757TT 2010-03-12 2018-10-24 Kombinirana terapija za liječenje raka dojke HRP20181757T1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31351510P 2010-03-12 2010-03-12
EP16166917.1A EP3117709B1 (en) 2010-03-12 2011-03-08 Combination therapy for treating breast cancer

Publications (1)

Publication Number Publication Date
HRP20181757T1 true HRP20181757T1 (hr) 2019-01-25

Family

ID=44563812

Family Applications (2)

Application Number Title Priority Date Filing Date
HRP20160932TT HRP20160932T1 (hr) 2010-03-12 2016-07-22 Kombinirana terapija za liječenje raka dojke
HRP20181757TT HRP20181757T1 (hr) 2010-03-12 2018-10-24 Kombinirana terapija za liječenje raka dojke

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HRP20160932TT HRP20160932T1 (hr) 2010-03-12 2016-07-22 Kombinirana terapija za liječenje raka dojke

Country Status (18)

Country Link
US (3) US8911736B2 (hr)
EP (4) EP3117709B1 (hr)
JP (2) JP5917418B2 (hr)
CY (1) CY1117831T1 (hr)
DK (2) DK3117709T3 (hr)
ES (2) ES2584433T3 (hr)
HK (1) HK1206936A1 (hr)
HR (2) HRP20160932T1 (hr)
HU (2) HUE040107T2 (hr)
LT (1) LT3117709T (hr)
ME (1) ME02464B (hr)
PL (2) PL2835053T3 (hr)
PT (2) PT3117709T (hr)
RS (2) RS57942B1 (hr)
SI (2) SI2835053T1 (hr)
SM (1) SMT201600253B (hr)
TR (1) TR201816180T4 (hr)
WO (1) WO2011112609A1 (hr)

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EP3117709B1 (en) * 2010-03-12 2018-08-01 Genzyme Corporation Combination therapy for treating breast cancer
US9782452B2 (en) * 2011-11-22 2017-10-10 Cornell University Methods for stimulating hematopoietic recovery by inhibiting TGFβ signaling
AR095240A1 (es) 2013-03-11 2015-09-30 Genzyme Corp ANTICUERPOS ANTI-TGF-b MODIFICADOS POR INGENIERÍA GENÉTICA Y FRAGMENTOS DE UNIÓN A ANTÍGENOS
WO2016094697A2 (en) * 2014-12-10 2016-06-16 The Regents Of The University Of Colorado, A Body Corporate Targeting breast cancer therapy based on stromal subtypes and cd146 composition
GB201503438D0 (en) 2015-02-27 2015-04-15 Ucl Business Plc Antibodies
DK3270823T3 (da) * 2015-03-18 2020-07-13 Med El Elektromedizinische Geraete Gmbh Fiksering af en knogleledende flydende massetransducer
KR102647231B1 (ko) 2018-08-02 2024-03-13 삼성전자주식회사 반도체 소자 및 이의 제조방법

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Also Published As

Publication number Publication date
EP2835053A1 (en) 2015-02-11
EP2544541B1 (en) 2014-10-08
EP3406141B1 (en) 2020-10-14
ES2694288T3 (es) 2018-12-19
TR201816180T4 (tr) 2018-11-21
EP3117709B1 (en) 2018-08-01
EP2544541A4 (en) 2013-07-31
DK3117709T3 (en) 2018-11-26
RS54972B1 (sr) 2016-11-30
LT3117709T (lt) 2018-11-26
US8911736B2 (en) 2014-12-16
HRP20160932T1 (hr) 2016-10-07
JP5917418B2 (ja) 2016-05-11
JP6289528B2 (ja) 2018-03-07
ES2584433T3 (es) 2016-09-27
DK2835053T3 (en) 2016-08-15
RS57942B1 (sr) 2019-01-31
US10507242B2 (en) 2019-12-17
ME02464B (me) 2017-02-20
PL3117709T3 (pl) 2019-01-31
EP2835053B1 (en) 2016-04-27
US9539325B2 (en) 2017-01-10
HK1206936A1 (zh) 2016-01-22
US20150086547A1 (en) 2015-03-26
PT2835053T (pt) 2016-07-14
SMT201600253B (it) 2016-08-31
US20170319691A1 (en) 2017-11-09
HUE027831T2 (en) 2016-11-28
CY1117831T1 (el) 2017-05-17
JP2016164174A (ja) 2016-09-08
SI2835053T1 (sl) 2016-09-30
EP2544541A1 (en) 2013-01-16
SI3117709T1 (sl) 2018-12-31
US20130034549A1 (en) 2013-02-07
WO2011112609A1 (en) 2011-09-15
JP2013522210A (ja) 2013-06-13
EP3406141A1 (en) 2018-11-28
PT3117709T (pt) 2018-11-15
HUE040107T2 (hu) 2019-02-28
PL2835053T3 (pl) 2016-12-30
EP3117709A1 (en) 2017-01-18

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