SK93198A3 - Quinoline-2-(1h)-one derivative, preparation method thereof and pharmaceutical composition containing the same - Google Patents
Quinoline-2-(1h)-one derivative, preparation method thereof and pharmaceutical composition containing the same Download PDFInfo
- Publication number
- SK93198A3 SK93198A3 SK931-98A SK93198A SK93198A3 SK 93198 A3 SK93198 A3 SK 93198A3 SK 93198 A SK93198 A SK 93198A SK 93198 A3 SK93198 A3 SK 93198A3
- Authority
- SK
- Slovakia
- Prior art keywords
- formula
- compound
- group
- quinolin
- methyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19601782A DE19601782A1 (de) | 1996-01-19 | 1996-01-19 | Chinolin-2-(1H)one |
| PCT/EP1997/000084 WO1997026244A1 (de) | 1996-01-19 | 1997-01-10 | Chinolin-2-(1h)-one |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SK93198A3 true SK93198A3 (en) | 1999-01-11 |
Family
ID=7783141
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK931-98A SK93198A3 (en) | 1996-01-19 | 1997-01-10 | Quinoline-2-(1h)-one derivative, preparation method thereof and pharmaceutical composition containing the same |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US6028080A (cs) |
| EP (1) | EP0885196A1 (cs) |
| JP (1) | JP2000503308A (cs) |
| KR (1) | KR19990077308A (cs) |
| CN (1) | CN1211974A (cs) |
| AR (1) | AR005646A1 (cs) |
| AU (1) | AU716230B2 (cs) |
| BR (1) | BR9707027A (cs) |
| CA (1) | CA2243474C (cs) |
| CZ (1) | CZ224098A3 (cs) |
| DE (1) | DE19601782A1 (cs) |
| HU (1) | HUP9900563A3 (cs) |
| MX (1) | MX9805700A (cs) |
| NO (1) | NO983333L (cs) |
| PL (1) | PL327829A1 (cs) |
| SK (1) | SK93198A3 (cs) |
| WO (1) | WO1997026244A1 (cs) |
| ZA (1) | ZA97364B (cs) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1246806B1 (en) * | 1999-11-03 | 2008-02-27 | AMR Technology, Inc. | Arly- and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine and serotonin |
| US7273889B2 (en) * | 2002-09-25 | 2007-09-25 | Innovative Drug Delivery Systems, Inc. | NMDA receptor antagonist formulation with reduced neurotoxicity |
| US7166738B2 (en) * | 2004-04-23 | 2007-01-23 | Roche Palo Alto Llc | Non-nucleoside reverse transcriptase inhibitors |
| US7625949B2 (en) | 2004-04-23 | 2009-12-01 | Roche Palo Alto Llc | Methods for treating retroviral infections |
| AU2006303368B2 (en) * | 2005-10-19 | 2011-05-26 | F. Hoffmann-La Roche Ag | Non-Nucleoside Reverse Transcriptase Inhibitors |
| WO2009102893A2 (en) * | 2008-02-14 | 2009-08-20 | Amira Pharmaceuticals, Inc. | CYCLIC DIARYL ETHER COMPOUNDS AS ANTAGONISTS OF PROSTAGLANDIN D2 receptors |
| US8497381B2 (en) | 2008-02-25 | 2013-07-30 | Panmira Pharmaceuticals, Llc | Antagonists of prostaglandin D2 receptors |
| US8415479B2 (en) | 2008-03-31 | 2013-04-09 | Renascience Co., Ltd. | Inhibitor of plasminogen activator inhibitor-1 |
| WO2009145989A2 (en) * | 2008-04-02 | 2009-12-03 | Amira Pharmaceuticals, Inc. | Aminoalkylphenyl antagonists of prostaglandin d2 receptors |
| GB2463788B (en) * | 2008-09-29 | 2010-12-15 | Amira Pharmaceuticals Inc | Heteroaryl antagonists of prostaglandin D2 receptors |
| US8378107B2 (en) | 2008-10-01 | 2013-02-19 | Panmira Pharmaceuticals, Llc | Heteroaryl antagonists of prostaglandin D2 receptors |
| WO2010057118A2 (en) | 2008-11-17 | 2010-05-20 | Amira Pharmaceuticals, Inc. | Heterocyclic antagonists of prostaglandin d2 receptors |
| EP2607348B8 (en) | 2009-03-31 | 2021-04-21 | Renascience Inc. | Plasminogen Activator Inhibitor-1 Inhibitor |
| CA2782085A1 (en) | 2010-01-06 | 2011-07-14 | Panmira Pharmaceuticals, Llc | Dp2 antagonist and uses thereof |
| EP2990057B1 (en) | 2013-04-15 | 2019-03-20 | Renascience Co., Ltd. | Pai-1 inhibitor for use in enhancing the antitumor effect of an antitumor agent in a patient |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5268378A (en) * | 1990-05-31 | 1993-12-07 | Merck Sharp & Dohme, Limited | Dioxo-tetrahydroquinoline derivatives |
| EP0459561B1 (en) * | 1990-05-31 | 1995-09-20 | MERCK SHARP & DOHME LTD. | Dioxo-tetrahydroquinoline derivatives |
| GB9022785D0 (en) * | 1990-10-19 | 1990-12-05 | Merck Sharp & Dohme | Therapeutic agents |
| GB9125515D0 (en) * | 1991-11-29 | 1992-01-29 | Merck Sharp & Dohme | Therapeutic agents |
| EP0685466A1 (de) * | 1994-06-02 | 1995-12-06 | Ciba-Geigy Ag | 3-Heteroaliphatyl- und 3-Hetero-(aryl)aliphatyl-2(1H)-chinolonderivate |
-
1996
- 1996-01-19 DE DE19601782A patent/DE19601782A1/de not_active Withdrawn
-
1997
- 1997-01-10 SK SK931-98A patent/SK93198A3/sk unknown
- 1997-01-10 CN CN97192395A patent/CN1211974A/zh active Pending
- 1997-01-10 AU AU13112/97A patent/AU716230B2/en not_active Ceased
- 1997-01-10 WO PCT/EP1997/000084 patent/WO1997026244A1/de not_active Application Discontinuation
- 1997-01-10 KR KR1019980705454A patent/KR19990077308A/ko not_active Application Discontinuation
- 1997-01-10 US US09/101,837 patent/US6028080A/en not_active Expired - Fee Related
- 1997-01-10 BR BR9707027A patent/BR9707027A/pt unknown
- 1997-01-10 EP EP97900586A patent/EP0885196A1/de not_active Withdrawn
- 1997-01-10 JP JP9525656A patent/JP2000503308A/ja not_active Withdrawn
- 1997-01-10 CZ CZ982240A patent/CZ224098A3/cs unknown
- 1997-01-10 PL PL97327829A patent/PL327829A1/xx unknown
- 1997-01-10 CA CA002243474A patent/CA2243474C/en not_active Expired - Fee Related
- 1997-01-10 HU HU9900563A patent/HUP9900563A3/hu unknown
- 1997-01-16 ZA ZA97364A patent/ZA97364B/xx unknown
- 1997-01-17 AR ARP970100184A patent/AR005646A1/es unknown
-
1998
- 1998-07-15 MX MX9805700A patent/MX9805700A/es unknown
- 1998-07-17 NO NO983333A patent/NO983333L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2000503308A (ja) | 2000-03-21 |
| NO983333L (no) | 1998-09-18 |
| NO983333D0 (no) | 1998-07-17 |
| ZA97364B (en) | 1997-07-22 |
| MX9805700A (es) | 1998-11-29 |
| AU1311297A (en) | 1997-08-11 |
| CA2243474A1 (en) | 1997-07-24 |
| CZ224098A3 (cs) | 1998-10-14 |
| PL327829A1 (en) | 1999-01-04 |
| US6028080A (en) | 2000-02-22 |
| CN1211974A (zh) | 1999-03-24 |
| AR005646A1 (es) | 1999-07-14 |
| BR9707027A (pt) | 1999-07-20 |
| HUP9900563A2 (hu) | 1999-06-28 |
| EP0885196A1 (de) | 1998-12-23 |
| DE19601782A1 (de) | 1997-07-24 |
| HUP9900563A3 (en) | 2000-02-28 |
| KR19990077308A (ko) | 1999-10-25 |
| CA2243474C (en) | 2009-10-27 |
| WO1997026244A1 (de) | 1997-07-24 |
| AU716230B2 (en) | 2000-02-24 |
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