SK67895A3 - - Google Patents

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Publication number
SK67895A3
SK67895A3 SK67895A SK67895A SK67895A3 SK 67895 A3 SK67895 A3 SK 67895A3 SK 67895 A SK67895 A SK 67895A SK 67895 A SK67895 A SK 67895A SK 67895 A3 SK67895 A3 SK 67895A3
Authority
SK
Slovakia
Prior art keywords
hemoglobin
column
hbao
solution
chromatography
Prior art date
Application number
SK67895A
Other languages
English (en)
Slovak (sk)
Other versions
SK281839B6 (sk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority claimed from ZA951034A external-priority patent/ZA951034B/xx
Publication of SK67895A3 publication Critical patent/SK67895A3/sk
Publication of SK281839B6 publication Critical patent/SK281839B6/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795—Porphyrin- or corrin-ring-containing peptides
    • C07K14/805—Haemoglobins; Myoglobins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/42—Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
    • B01D15/422—Displacement mode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SK678-95A 1993-09-21 1994-09-20 Spôsob separácie vopred vybraného druhu hemoglobínu SK281839B6 (sk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CA002106612A CA2106612C (en) 1993-09-21 1993-09-21 Displacement chromatography process
PCT/CA1994/000514 WO1995008574A1 (en) 1993-09-21 1994-09-20 Displacement chromatography process and purified hemoglobin product
ZA951034A ZA951034B (en) 1993-09-21 1995-02-09 Displacements chromatography process and purified hemoglobin product

Publications (2)

Publication Number Publication Date
SK67895A3 true SK67895A3 (cs) 1995-09-13
SK281839B6 SK281839B6 (sk) 2001-08-06

Family

ID=25676656

Family Applications (1)

Application Number Title Priority Date Filing Date
SK678-95A SK281839B6 (sk) 1993-09-21 1994-09-20 Spôsob separácie vopred vybraného druhu hemoglobínu

Country Status (9)

Country Link
US (1) US5439591A (cs)
EP (1) EP0668877B1 (cs)
CN (1) CN1051317C (cs)
AU (1) AU681438B2 (cs)
CA (1) CA2106612C (cs)
CZ (1) CZ287589B6 (cs)
PL (1) PL179525B1 (cs)
SK (1) SK281839B6 (cs)
WO (1) WO1995008574A1 (cs)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5545328A (en) * 1993-09-21 1996-08-13 Hemosol Inc. Purification of hemoglobin by displacement chromatography
US5741894A (en) * 1995-09-22 1998-04-21 Baxter International, Inc. Preparation of pharmaceutical grade hemoglobins by heat treatment in partially oxygenated form
AU733714B2 (en) * 1996-08-27 2001-05-24 Hemosol Inc. Enhanced stimulation of erythropoiesis
US5814601A (en) * 1997-02-28 1998-09-29 The Regents Of The University Of California Methods and compositions for optimization of oxygen transport by cell-free systems
JP4583510B2 (ja) * 1997-02-28 2010-11-17 ザ リージェンツ オブ ザ ユニバーシティー オブ カリフォルニア 無細胞系による酸素輸送の最適化のための方法と組成物
US5851400A (en) * 1997-03-21 1998-12-22 University Of Maryland At Baltimore County Method for eliminating the displacer in displacement chromatography of proteins
US6423233B1 (en) * 2000-08-15 2002-07-23 Biogal Gyogyszergyar Rt. Purification process
GB9707696D0 (en) * 1997-04-16 1997-06-04 Agner Erik Improvements in or relating to chromatography
US6239262B1 (en) 1998-01-07 2001-05-29 Rensselaer Polytechnic Institute Low molecular weight displacers for protein purification in hydrophobic interaction and reversed phase chromatographic systems
CA2233725A1 (en) * 1998-03-31 1999-09-30 Hemosol Inc. Hemoglobin-hydroxyethyl starch complexes
GB9822963D0 (en) * 1998-10-20 1998-12-16 Agner Erik Improvements in or relating to chromatography
US6573373B1 (en) 1999-06-29 2003-06-03 Isis Pharmaceuticals, Inc. High affinity, low molecular weight displacers for oligonucleotide purification
US6747132B2 (en) 2000-11-29 2004-06-08 Apex Biosciences, Inc. Methods for the synthesis of a modified hemoglobin solution
US7195923B2 (en) * 2001-01-31 2007-03-27 Scripps Laboratories, Inc. Ratiometric determination of glycated protein
CA2437381C (en) 2001-02-01 2012-03-27 Sigma-Aldrich Co. Improved affinity matrices with enhanced visibility for molecular pull-down and immunoprecipitation applications
US20030153491A1 (en) * 2002-01-11 2003-08-14 Winslow Robert M. Methods and compositions for oxygen transport comprising a high oxygen affinity modified hemoglobin
US20050164915A1 (en) * 2002-04-01 2005-07-28 Sangart, Inc. Compositions for oxygen transport comprising a high oxygen affinity modified hemoglobin
WO2003074148A1 (en) 2002-02-28 2003-09-12 Rensselaer Polytechnic Institute High-affinity, low-molecular-mass displacers for ion-exchange chromatography
JP3912206B2 (ja) * 2002-07-05 2007-05-09 株式会社日立製作所 筒内直接燃料噴射装置用燃料ポンプ
MX2007011129A (es) 2005-03-11 2007-11-06 Wyeth Corp Un metodo de cromatografia de particion debil.
JP2008537153A (ja) * 2005-04-22 2008-09-11 ウオーターズ・インベストメンツ・リミテツド 生体高分子の質量分析管理された精製のための装置および方法
ES2455166T3 (es) * 2005-12-02 2014-04-14 Sachem, Inc. Procedimiento de cromatografía de desplazamiento de intercambio aniónico
US7976708B2 (en) * 2008-05-12 2011-07-12 Secretary, Department of Atormic Energy Innovative cut-and-feed operation for enhancing the performance of ion-exchange chromatographic separation
HUE066562T2 (hu) † 2008-08-14 2024-08-28 Genentech Inc Eljárások szennyezés eltávolítására indigén fehérje kiszorításos ioncserés membrán kromatográfia alkalmazásával
AU2010292897B2 (en) 2009-08-06 2016-01-07 Genentech, Inc. Method to improve virus removal in protein purification
US8304248B2 (en) * 2009-11-16 2012-11-06 Torres Anthony R Protein separation via ion-exchange chromatography and associated methods, systems, and devices
EP4492053A3 (en) * 2010-05-25 2025-03-19 F. Hoffmann-La Roche AG Methods of purifying polypeptides
US20130331554A1 (en) 2010-11-15 2013-12-12 Biogen Idec Inc. Enrichment and concentration of select product isoforms by overloaded bind and elute chromatography
US8293115B2 (en) * 2011-01-20 2012-10-23 Gordon Rossiter Ionic impurities rejection and chromatographic purification using ion exchange
GB201103363D0 (en) * 2011-02-28 2011-04-13 Ge Healthcare Uk Ltd Sample preservation method and sample application substrate
KR20140091721A (ko) * 2011-11-02 2014-07-22 제넨테크, 인크. 오버로드 및 용리 크로마토그래피
WO2013075740A1 (en) 2011-11-23 2013-05-30 Sanofi Antibody purification method
CN103665098B (zh) * 2012-09-20 2015-08-05 中国科学院大连化学物理研究所 双相柱膜蛋白质微反应器及其应用
TWI675041B (zh) 2013-05-06 2019-10-21 法商賽諾菲公司 用於純化抗體之連續多步驟方法
EP3546475A1 (en) 2018-03-27 2019-10-02 Sanofi Full flow-through process for purifying recombinant proteins
WO2019203302A1 (ja) * 2018-04-18 2019-10-24 積水メディカル株式会社 ヘモグロビン分析方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3971842A (en) * 1974-08-08 1976-07-27 Atlantic Richfield Company Continuous displacement chromatographic separation
FR2548670B1 (fr) * 1983-07-07 1985-10-25 Merieux Inst Procede de preparation des principales proteines du sang hemolyse sous forme non denaturee
JPS6075530A (ja) * 1983-09-30 1985-04-27 Asahi Chem Ind Co Ltd 金属元素の新しい分離精製方法
CA1244349A (en) * 1985-06-26 1988-11-08 Jen-Chang Hsia Purification of hemoglobin and modified hemoglobin by affinity chromatography
US5084558A (en) * 1987-10-13 1992-01-28 Biopure Corporation Extra pure semi-synthetic blood substitute
US5340474A (en) * 1988-03-24 1994-08-23 Terrapin Technologies, Inc. Panels of analyte-binding ligands
CA1338244C (en) * 1988-08-17 1996-04-09 Xiang-Fu Wu Purification of hemoglobin and methemoglobin by bioselective elution
US5028696A (en) * 1988-10-28 1991-07-02 Torres Anthony R Ion exchange and separation method
US5149436A (en) * 1988-11-28 1992-09-22 Union Oil Company Of California Continuous displacement chromatographic method
IT1232311B (it) * 1989-09-04 1992-01-28 Sclavo Spa Metodo di purificazione di composti a struttura peptidica o pseudo peptidica a basso peso molecolare.
US5264555A (en) * 1992-07-14 1993-11-23 Enzon, Inc. Process for hemoglobin extraction and purification

Also Published As

Publication number Publication date
CA2106612A1 (en) 1995-03-22
CN1114836A (zh) 1996-01-10
WO1995008574A1 (en) 1995-03-30
EP0668877B1 (en) 1999-01-20
CA2106612C (en) 2001-02-06
US5439591A (en) 1995-08-08
SK281839B6 (sk) 2001-08-06
CZ128795A3 (en) 1995-12-13
PL179525B1 (pl) 2000-09-29
AU681438B2 (en) 1997-08-28
CN1051317C (zh) 2000-04-12
EP0668877A1 (en) 1995-08-30
PL309034A1 (en) 1995-09-18
CZ287589B6 (en) 2000-12-13
AU7650394A (en) 1995-04-10

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