SK5232002A3 - Bicyclic amino acids as pharmaceutical agents - Google Patents
Bicyclic amino acids as pharmaceutical agents Download PDFInfo
- Publication number
- SK5232002A3 SK5232002A3 SK523-2002A SK5232002A SK5232002A3 SK 5232002 A3 SK5232002 A3 SK 5232002A3 SK 5232002 A SK5232002 A SK 5232002A SK 5232002 A3 SK5232002 A3 SK 5232002A3
- Authority
- SK
- Slovakia
- Prior art keywords
- acetic acid
- aminomethyl
- aminomethylbicyclo
- compound
- hept
- Prior art date
Links
- -1 Bicyclic amino acids Chemical class 0.000 title claims description 82
- 239000008177 pharmaceutical agent Substances 0.000 title description 2
- 150000001875 compounds Chemical class 0.000 claims abstract description 89
- 150000003839 salts Chemical class 0.000 claims abstract description 17
- 206010015037 epilepsy Diseases 0.000 claims abstract description 7
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims description 316
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- ONKWZNBXHSMMDK-UHFFFAOYSA-N 2-[2-(aminomethyl)-1,3,3a,4,5,6,7,7a-octahydroinden-2-yl]acetic acid Chemical compound C1CCCC2CC(CN)(CC(O)=O)CC21 ONKWZNBXHSMMDK-UHFFFAOYSA-N 0.000 claims description 19
- NDDZVQRQVFTNSN-UHFFFAOYSA-N 2-[3-(aminomethyl)-3-bicyclo[3.2.0]heptanyl]acetic acid Chemical compound C1C(CN)(CC(O)=O)CC2CCC21 NDDZVQRQVFTNSN-UHFFFAOYSA-N 0.000 claims description 19
- GSBZRDSCOPXLJJ-UHFFFAOYSA-N 2-[2-(aminomethyl)-3,3a,4,5,6,6a-hexahydro-1h-pentalen-2-yl]acetic acid Chemical compound C1CCC2CC(CN)(CC(O)=O)CC21 GSBZRDSCOPXLJJ-UHFFFAOYSA-N 0.000 claims description 14
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16072599P | 1999-10-20 | 1999-10-20 | |
| PCT/US2000/028687 WO2001028978A1 (en) | 1999-10-20 | 2000-10-17 | Bicyclic amino acids as pharmaceutical agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SK5232002A3 true SK5232002A3 (en) | 2003-07-01 |
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| Application Number | Title | Priority Date | Filing Date |
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| SK523-2002A SK5232002A3 (en) | 1999-10-20 | 2000-10-17 | Bicyclic amino acids as pharmaceutical agents |
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| US7164034B2 (en) | 1999-06-10 | 2007-01-16 | Pfizer Inc. | Alpha2delta ligands for fibromyalgia and other disorders |
| HUP0300833A3 (en) * | 2000-06-26 | 2009-08-28 | Warner Lambert Co | Gabapentin analogues for treating sleep disorders |
| US6620829B2 (en) | 2000-10-17 | 2003-09-16 | Warner-Lambert Company | Method of treating noninflammatory cartilage damage |
| EP1226820A1 (en) * | 2001-01-26 | 2002-07-31 | Warner-Lambert Company | Use of bicyclic amino acids for preventing and treating visceral pain and gastrointestinal disorders |
| OA12504A (en) * | 2001-04-19 | 2006-05-29 | Warner Lambert Co | Fused bicyclic or tricyclic amino acids. |
| GB2375108A (en) * | 2001-05-04 | 2002-11-06 | Warner Lambert Co | Production of a bicycloheptanone |
| GB2375109A (en) * | 2001-05-04 | 2002-11-06 | Warner Lambert Co | Process for preparing bicyclic amino acid |
| US8048917B2 (en) | 2005-04-06 | 2011-11-01 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| US7186855B2 (en) | 2001-06-11 | 2007-03-06 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
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